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2-Amino-4,5-dihydrothiazole-4-carboxylic acid

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Identification
Molecular formula
C4H7N2O2S
CAS number
98741-96-7
IUPAC name
2-amino-4,5-dihydrothiazole-4-carboxylic acid
State
State
The compound is typically found as a solid at room temperature. It is stable under normal conditions and should be stored in a sealed container to avoid moisture absorption.
Melting point (Celsius)
219.00
Melting point (Kelvin)
492.00
Boiling point (Celsius)
265.00
Boiling point (Kelvin)
538.00
General information
Molecular weight
146.18g/mol
Molar mass
146.1830g/mol
Density
1.5408g/cm3
Appearence

2-Amino-4,5-dihydrothiazole-4-carboxylic acid typically appears as a crystalline solid. The solid form can vary in color, often appearing white or off-white, depending on purity and specific conditions of crystallization. It can also absorb moisture, altering its appearance slightly.

Comment on solubility

Solubility of 2-amino-4,5-dihydrothiazole-4-carboxylic acid

The solubility of 2-amino-4,5-dihydrothiazole-4-carboxylic acid in various solvents can be influenced by its chemical structure, which features both an amino group and a carboxylic acid group. These functional groups can significantly affect how the compound interacts with solvents. Here are some important insights:

  • Polar solvents: This compound is likely to exhibit good solubility in polar solvents such as water due to its ability to form hydrogen bonds with the solvent molecules.
  • Non-polar solvents: Conversely, solubility in non-polar solvents may be limited, as the compound lacks significant hydrophobic character.
  • Effect of pH: The solubility may also change with pH; for instance, at lower pH levels, the carboxylic acid may be protonated, which could diminish its solubility.
  • Concentration factors: Higher concentrations of the compound might lead to precipitation, indicating that the solubility limit can depend on the concentration and temperature of the solution.

To sum up, while 2-amino-4,5-dihydrothiazole-4-carboxylic acid is expected to be soluble in polar environments, its solubility profile can vary based on factors like pH and solvent choice. As noted in chemical literature, understanding these solubility characteristics is crucial for applications in pharmaceutical and biochemical contexts.

Interesting facts

Interesting Facts about 2-amino-4,5-dihydrothiazole-4-carboxylic acid

2-amino-4,5-dihydrothiazole-4-carboxylic acid is a fascinating compound with various applications in the field of chemistry and biotechnology. Here are some engaging insights about this intriguing molecule:

  • Structural Characteristics: This compound features a thiazole ring, which is essential in many biological systems. The presence of an amino group and a carboxylic acid moiety makes it an interesting target for modifications in medicinal chemistry.
  • Key Uses: 2-amino-4,5-dihydrothiazole-4-carboxylic acid serves as a critical building block in the synthesis of various pharmaceuticals, particularly in the development of antimicrobial agents.
  • Biological Significance: The thiazole ring is commonly found in vitamin B1 (thiamine), indicating the compound's potential importance in biological processes.
  • Research Potential: Due to its unique structure, this compound is of interest for research in the development of novel therapeutics and agrochemicals, paving the way for innovative solutions in health and agriculture.

Scientists are continually exploring the diverse functionalities and potential applications of 2-amino-4,5-dihydrothiazole-4-carboxylic acid, making it a relevant topic in both academia and industry. As noted by researchers, "The versatility of thiazole derivatives in medicinal chemistry cannot be overstated." This compound exemplifies how small structural changes can lead to significant variations in activity and application.

Synonyms
2150-55-2
2-Amino-2-thiazoline-4-carboxylic acid
4-Thiazolecarboxylic acid, 2-amino-4,5-dihydro-
2-Aminothiazoline-4-carboxylic Acid
2-Amino-4-carboxythiazoline
2-Amino-4,5-dihydro-1,3-thiazole-4-carboxylic acid
2-Thiazoline-4-carboxylic acid, 2-amino-
2-Iminothiazolidine-4-carboxylic Acid
NSC 25069
EINECS 218-433-0
2-Amino-delta(2)-thiazoline-4-carboxylic acid
NSC-25069
48431VN59G
DL-2-Aminothiazoline-4-carboxylic Acid
DL-2-Amino-2-thiazolin-4-carboxylic Acid
DTXSID9024510
CHEBI:64777
2-azanyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid
DL-2-AMINO-.DELTA.2-THIAZOLINE-4-CARBOXYLIC ACID
2-aminothiazoline-4-CA
DTXCID704510
2-amino-delta(2)-thiazolin-4-carbonic acid
DL-2-AMINO-DELTA2-THIAZOLINE-4-CARBOXYLIC ACID
2-Amino-4,5-dihydrothiazole-4-carboxylic acid
2-Amino-4-thiazolinic acid
DL-2-Amino-2-thiazoline-4-carboxylic Acid
rac 2-Aminothiazoline-4-carboxylic Acid
L-2-Aminothiazoline-4-carboxylic Acid
D-2-Aminothiazoline-4-carboxylic Acid
2-Amino-4,5-dihydro-4-thiazolecarboxylic Acid
NSC25069
MFCD00010067
2-AMINO-4-THIAZOLINE-4-CARBOXYLIC ACID
4-Thiazolecarboxylicacid,2-amino-4,5-dihydro-,(4S)-(9CI)
SCHEMBL272903
UNII-48431VN59G
AC-076
STL300750
AKOS005145103
AKOS007930201
AS-20115
2-Amino-4-carboxythiazole, 4,5-dihydro-
DB-002420
DB-329884
2-amino-Delta2-thiazoline-4-carboxylic acid
CS-0044002
NS00049828
2-Amino-4,5-dihydrothiazole-4-carboxylicacid
4-Thiazolecarboxylicacid,2-amino-4,5-dihydro-
2-amino-4,5-dihydro-thiazole-4-carboxylic acid
Q27133419
2-Amino-4,5-dihydro-1,3-thiazole-4-carboxylic acid #
(SR)-2-Amino-4,5-dihydro-1,3-thiazole-4-carboxylic acid