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Metamizole

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Identification
Molecular formula
C10H13N3O4
CAS number
443-48-1
IUPAC name
2-amino-5-[2-[4-(hydroxymethyl)phenyl]hydrazino]-5-oxo-pentanoic acid
State
State

Metamizole is typically found in a solid state at room temperature.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.15
Boiling point (Celsius)
297.00
Boiling point (Kelvin)
570.15
General information
Molecular weight
303.35g/mol
Molar mass
303.3490g/mol
Density
1.2389g/cm3
Appearence

Metamizole typically appears as a white or off-white crystalline powder. It is odorless or may have a slight smell, depending on its purity and form.

Comment on solubility

Solubility of 2-amino-5-[2-[4-(hydroxymethyl)phenyl]hydrazino]-5-oxo-pentanoic acid

The solubility of 2-amino-5-[2-[4-(hydroxymethyl)phenyl]hydrazino]-5-oxo-pentanoic acid in various solvents can present interesting challenges due to its complex structure.

Key factors influencing the solubility include:

  • Polarity: This compound contains both hydrophobic (the phenyl group) and hydrophilic (the amino and carboxylic acid groups) characteristics, suggesting it may have moderate solubility in polar solvents such as water.
  • pH Sensitivity: Being an amino acid derivative, its solubility can significantly vary with pH due to the protonation and deprotonation of its functional groups, enhancing solubility at different pH levels.
  • Hydrogen Bonding: The presence of hydroxymethyl and amino groups can lead to extensive hydrogen bonding with water molecules, potentially increasing its solubility.

As a result, this compound may exhibit:

  • Higher solubility in: Aqueous solutions, especially under acidic conditions.
  • Lower solubility in: Organic solvents that lack the ability to interact favorably with polar groups.

In summary, while the solubility of 2-amino-5-[2-[4-(hydroxymethyl)phenyl]hydrazino]-5-oxo-pentanoic acid can be anticipated to be relatively good in polar solvents, its exact behavior will depend on environmental conditions, highlighting the complexity of predicting solubility for compounds of this nature.

Interesting facts

2-amino-5-[2-[4-(hydroxymethyl)phenyl]hydrazino]-5-oxo-pentanoic acid: A Unique Compound

This intriguing compound belongs to a class of molecules that exhibit fascinating biological activities. One of the remarkable aspects of 2-amino-5-[2-[4-(hydroxymethyl)phenyl]hydrazino]-5-oxo-pentanoic acid is its potential as a pharmaceutical intermediate. Scientists are particularly interested in its reactivity and how it can be utilized in drug development processes.

Biological Significance

  • Antioxidant Properties: Preliminary studies suggest that this compound may exhibit antioxidant effects, which can be beneficial in preventing cellular damage.
  • Antitumor Activity: There is ongoing research into its potential role in oncology, particularly in the context of cancer cell inhibition.
  • Enzyme Inhibitor: The structure hints at possible enzyme inhibition capabilities, highlighting its relevance in metabolic pathways.

In addition to its biological roles, the compound's synthesis may involve creative organic chemistry techniques that give rise to innovative methodologies in drug synthesis. This experimentation not only enhances the understanding of hydrazine derivatives but also lends insights into the broader field of convergent synthesis.

Applications and Research Potential

Key areas of research might include:

  • Developing new therapeutic agents by modifying its structure for higher efficacy.
  • Examining its interactions with various biological targets to establish specific applications in biochemistry.
  • Exploring the relationship between structure and function to unlock more of its potential.

In conclusion, 2-amino-5-[2-[4-(hydroxymethyl)phenyl]hydrazino]-5-oxo-pentanoic acid serves not only as a fascinating subject for academic inquiry but also as a promising candidate in the pursuit of new medicinal compounds. As researchers continue to delve into its properties, this compound might unveil new opportunities in science and medicine.

Synonyms
L-Agaritine
2-amino-5-[2-[4-(hydroxymethyl)phenyl]hydrazinyl]-5-oxopentanoic acid
2-Amino-5-{2-[4-(hydroxymethyl)phenyl]hydrazinyl}-5-oxopentanoic acid
SCHEMBL2678853
DTXSID30859765
CHEBI:191700
CAA75790
Q55214070