Skip to main content

Mitomycin C

ADVERTISEMENT
Identification
Molecular formula
C15H18N4O5
CAS number
50-07-7
IUPAC name
2-amino-5-[[2-(carboxymethylamino)-1-[(9-hydroxy-7,8-dioxo-9,10-dihydrobenzo[a]pyren-10-yl)sulfanylmethyl]-2-oxo-ethyl]amino]-5-oxo-pentanoic acid
State
State

Mitomycin C is typically found as a solid at room temperature. It is a stable compound under normal conditions but should be kept dry and stored away from light and heat.

Melting point (Celsius)
360.00
Melting point (Kelvin)
633.15
Boiling point (Celsius)
392.25
Boiling point (Kelvin)
665.40
General information
Molecular weight
334.32g/mol
Molar mass
334.3210g/mol
Density
0.8570g/cm3
Appearence

Mitomycin C is a blue-violet crystalline powder. It is soluble in organic solvents and slightly soluble in water. When dissolved, it exhibits a vibrant blue coloration.

Comment on solubility

Solubility of 2-amino-5-[[2-(carboxymethylamino)-1-[(9-hydroxy-7,8-dioxo-9,10-dihydrobenzo[a]pyren-10-yl)sulfanylmethyl]-2-oxo-ethyl]amino]-5-oxo-pentanoic acid

The solubility of the compound 2-amino-5-[[2-(carboxymethylamino)-1-[(9-hydroxy-7,8-dioxo-9,10-dihydrobenzo[a]pyren-10-yl)sulfanylmethyl]-2-oxo-ethyl]amino]-5-oxo-pentanoic acid (C15H18N4O5) can be quite complex, owing to its intricate molecular structure that includes various functional groups influencing its behavior in solvents.

Key Factors Affecting Solubility:

  • Polarity: The presence of multiple polar functional groups, such as amino and carboxyl groups, typically enhances solubility in polar solvents like water.
  • Hydrophobic Regions: The hydrocarbon component of the compound can lead to some degree of hydrophobic behavior, which may reduce solubility in aqueous solutions.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds with solvent molecules can significantly increase its solubility in appropriate solvents.
  • pH Dependence: Solubility might vary with pH, particularly for compounds with acidic or basic functional groups, as their ionization states can change.

In summary, the solubility of 2-amino-5-[[2-(carboxymethylamino)-1-[(9-hydroxy-7,8-dioxo-9,10-dihydrobenzo[a]pyren-10-yl)sulfanylmethyl]-2-oxo-ethyl]amino]-5-oxo-pentanoic acid is largely determined by the interplay of its polar and nonpolar characteristics, its ability to engage in intermolecular interactions, and its dependency on environmental conditions such as pH. For practical applications, experimental solubility testing in various solvents would provide valuable insights into its behavior and potential uses.

Interesting facts

Interesting Facts about 2-amino-5-[[2-(carboxymethylamino)-1-[(9-hydroxy-7,8-dioxo-9,10-dihydrobenzo[a]pyren-10-yl)sulfanylmethyl]-2-oxo-ethyl]amino]-5-oxo-pentanoic acid

This compound is a fascinating example of a complex organic molecule that merges elements of both amino acids and aromatic compounds, reflecting the intricate tapestry of biological chemistry. Here are some noteworthy aspects:

  • Multifunctionality: This compound possesses multiple functional groups, including amino, carboxyl, and carbonyl groups, which enable it to engage in a variety of chemical reactions. This versatility is fundamental in biochemical pathways.
  • Role in Biochemistry: As a derivative of amino acids, it can be involved in protein synthesis and enzyme function, suggesting potential applications in medicinal chemistry to target specific biological functions.
  • Structural Complexity: The presence of a dioxo-phenanthrene moiety imparts distinct structural characteristics, enhancing interactions with biomolecules. The complexity of its structure makes it an excellent candidate for research into molecular recognition and specificity.
  • Potential Therapeutic Applications: Due to its unique structure and functional groups, this compound may hold promise in drug design, particularly in targeting cancer and other diseases where oxidative stress plays a significant role.
  • Investigation of Sulfanyl Groups: The sulfanylmethyl aspect of the molecule invites further exploration of sulfur's role in biological systems, particularly in redox reactions and its effect on pharmacokinetics.

Overall, 2-amino-5-[[2-(carboxymethylamino)-1-[(9-hydroxy-7,8-dioxo-9,10-dihydrobenzo[a]pyren-10-yl)sulfanylmethyl]-2-oxo-ethyl]amino]-5-oxo-pentanoic acid is a prime example of how complex organic compounds can interact with biological systems, offering a wealthy field for further research and potential therapeutic developments.