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5-Aminosalicylic acid

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Identification
Molecular formula
C7H7NO3
CAS number
89-57-6
IUPAC name
2-amino-5-(4-amino-3-carboxy-phenyl)benzoic acid
State
State

Solid at room temperature. It is stable under normal temperatures and pressures.

Melting point (Celsius)
275.00
Melting point (Kelvin)
548.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
153.14g/mol
Molar mass
153.1360g/mol
Density
1.5020g/cm3
Appearence

5-Aminosalicylic acid is typically seen as a white to slightly pinkish crystalline powder. Its appearance may vary depending on the form it is in, but generally, as a solid compound, it maintains this granular and powdery form.

Comment on solubility

Solubility of 2-amino-5-(4-amino-3-carboxy-phenyl)benzoic acid

When considering the solubility of 2-amino-5-(4-amino-3-carboxy-phenyl)benzoic acid, it is important to note the following:

  • Polarity: The presence of multiple amino and carboxy groups contributes to the compound's polarity, enhancing its ability to interact with polar solvents such as water.
  • Hydrogen Bonding: The amino (-NH2) and carboxy (-COOH) functional groups can form significant hydrogen bonds with water, which generally increases solubility in aqueous environments.
  • pH Dependency: The solubility of this compound may vary with pH; at lower pH levels, the carboxylic acid group may remain protonated, potentially affecting overall solubility.
  • Temperature Effects: Like many organic compounds, solubility can also be affected by temperature increases, often leading to higher solubility in warmer conditions.

In summary, this compound's solubility profile is predominantly characterized by its ability to dissolve in polar solvents owing to its functional groups. However, factors such as pH and temperature must be carefully considered when predicting solubility behavior. Understanding these dynamics is crucial for applications in various fields, including pharmaceuticals and materials science.

Interesting facts

Interesting Facts about 2-amino-5-(4-amino-3-carboxy-phenyl)benzoic acid

2-amino-5-(4-amino-3-carboxy-phenyl)benzoic acid, commonly recognized as a derivative of benzoic acid, is a compound of significant interest in the field of medicinal chemistry. Here are some fascinating details:

  • Dual Functionalities: This compound contains both amino and carboxylic acid functional groups, which makes it an interesting candidate for various biochemical applications. The amino groups can form hydrogen bonds with other molecules, enhancing its interaction in biological systems.
  • Potential in Drug Design: Due to its structural characteristics, it may play a role in drug development, particularly in the design of molecules that target specific enzymes or receptors in the human body.
  • Research Applications: The compound is studied for its potential use in treatments for conditions such as cancer and inflammatory diseases, where the inhibition of certain pathways can lead to therapeutic benefits.
  • Amino Acid Analogs: As an amino acid analog, this compound can be utilized to understand the mechanisms of action of natural amino acids in metabolic pathways. Its structural similarities allow researchers to investigate modifications and their effects on biological activity.
  • Analytical Chemistry: The compound's unique structure makes it suitable for various analytical techniques, such as chromatography and spectroscopy, which help in elucidating its properties and function in complex mixtures.

In summary, 2-amino-5-(4-amino-3-carboxy-phenyl)benzoic acid embodies a blend of biological significance and chemical versatility. As a starting point for further research, it stands out in the landscape of chemical compounds, inviting scientists to explore its potential.

Synonyms
2130-56-5
Benzidine-3,3'-dicarboxylic acid
4,4'-diaminobiphenyl-3,3'-dicarboxylic acid
5,5'-Bianthranilic acid
5,5'-Dianthranilic acid
3,3'-Benzidinedicarboxylic acid
Benzidine-M,M'-dicarboxylic acid
3,3'-DICARBOXYBENZIDINE
PLU8S18T9F
HSDB 2738
4,4'-Diamino-3,3'-biphenyldicarboxylic acid
EINECS 218-348-9
Kwas benzydynodwukaroksylowy [Polish]
3,3'-Biphenyldicarboxylic acid, 4,4'-diamino-
Kwas benzydynodwukaroksylowy
BRN 2815505
DTXSID4062195
3,3'-dicarboxy-4,4'-diaminobiphenyl
(1,1'-Biphenyl)-3,3'-dicarboxylic acid, 4,4'-diamino-
[1,1'-Biphenyl]-3,3'-dicarboxylic acid, 4,4'-diamino-
3,3'-DICARBOXYBENZIDINE [HSDB]
2-14-00-00345 (Beilstein Handbook Reference)
1,1'-BIPHENYL)-3,3'-DICARBOXYLIC ACID, 4,4'-DIAMINO-
5,5'Bianthranilic acid
5,5'Dianthranilic acid
Benzidinem,m'dicarboxylic acid
3,3'Benzidinedicarboxylic acid
Benzidine3,3'dicarboxylic acid
DTXCID2036459
4,4'Diamino3,3'biphenyldicarboxylic acid
3,3'Biphenyldicarboxylic acid, 4,4'diamino
(1,1'Biphenyl)3,3'dicarboxylic acid, 4,4'diamino
218-348-9
2-amino-5-(4-amino-3-carboxyphenyl)benzoic acid
4,4'-DIAMINO-[1,1'-BIPHENYL]-3,3'-DICARBOXYLIC ACID
[1,1'-Biphenyl]-3,3'-dicarboxylicacid, 4,4'-diamino-
UNII-PLU8S18T9F
Cambridge id 5180176
Oprea1_205130
CBDivE_004675
MLS000703166
SCHEMBL352643
YSCH0291
CHEMBL1584156
IIQLVLWFQUUZII-UHFFFAOYSA-N
HMS2743C23
benzidine-3,3' -dicarboxylic acid
STL512801
AKOS022507511
NCGC00245477-01
SMR000273630
CS-0360211
NS00026833
G83483
Q27286625
4,4'-DIAMINO-[1,1'-BIPHENYL]-3,3'-DICARBOXYLICACID