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Aminophenol

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Identification
Molecular formula
C12H12N2O2
CAS number
122-78-1
IUPAC name
2-amino-5-(4-amino-3-hydroxy-phenyl)phenol
State
State

At room temperature, this compound is typically a solid. It is stable under normal conditions but should be kept away from strong oxidizing agents to prevent reactive degradation.

Melting point (Celsius)
167.50
Melting point (Kelvin)
440.65
Boiling point (Celsius)
572.15
Boiling point (Kelvin)
845.15
General information
Molecular weight
217.24g/mol
Molar mass
217.2370g/mol
Density
1.4313g/cm3
Appearence

2-Amino-5-(4-amino-3-hydroxy-phenyl)phenol appears as a crystalline solid that is typically off-white or light brown in color. It may be available as a powder or in crystalline form. The compound may darken upon exposure to air or light due to oxidation.

Comment on solubility

Solubility of 2-amino-5-(4-amino-3-hydroxy-phenyl)phenol

The solubility of 2-amino-5-(4-amino-3-hydroxy-phenyl)phenol, a complex organic compound, is influenced by its functional groups and molecular structure. Here are some key points to consider:

  • Polar vs. Nonpolar: The presence of hydroxyl (-OH) groups, along with amino (-NH2) groups, enhances the compound's polarity, resulting in increased solubility in polar solvents such as water.
  • Hydrogen Bonding: The capability to form hydrogen bonds plays a significant role in solubility. Compounds that can engage in hydrogen bonding with solvent molecules typically show better solubility.
  • Solvent Compatibility: 2-amino-5-(4-amino-3-hydroxy-phenyl)phenol is expected to be less soluble in nonpolar solvents due to the lack of similar interactions. Examples of nonpolar solvents are benzene and hexane, where solubility may be minimal.
  • pH Dependence: The ionization of amino groups can affect solubility. In acidic or basic solutions, the compound may exist in different ionic forms, impacting its solubility profile.

In summary, while this compound shows good solubility in polar solvents due to strong intermolecular interactions, its solubility decreases significantly in nonpolar environments. Thus, it is essential to consider both the chemical structure and the solvent characteristics when evaluating solubility.

Interesting facts

Interesting Facts about 2-amino-5-(4-amino-3-hydroxy-phenyl)phenol

2-amino-5-(4-amino-3-hydroxy-phenyl)phenol, often referred to within scientific circles for its intricate molecular structure, is notable for several reasons:

  • Biological Significance: This compound demonstrates potential biological activities, particularly in the realm of medicinal chemistry. It has been studied for its effects on various biochemical pathways, making it of interest in drug development.
  • Colorimetric Applications: Its unique structure permits it to serve as a chromogenic indicator. This means it changes color in response to specific chemical environments, which can be extremely useful in analytical chemistry for detecting the presence of particular substances.
  • Antioxidant Properties: Research has indicated that certain phenolic compounds can exhibit antioxidant capabilities, which help in scavenging free radicals and reducing oxidative stress in biological systems. This opens pathways for its use in health-related applications.
  • Synthetic Versatility: The presence of multiple functional groups in this compound allows it to participate in various chemical reactions, making it a useful building block in synthesizing more complex molecules.

In summary, 2-amino-5-(4-amino-3-hydroxy-phenyl)phenol is not just an ordinary compound; it symbolizes the intersection of chemistry with potential real-world applications. With ongoing research, we may uncover even more intriguing uses, highlighting the importance of such compounds in both environmental and human health domains.

Synonyms
3,3'-DIHYDROXYBENZIDINE
2373-98-0
4,4'-Diamino-3,3'-biphenyldiol
3,3'-Dioxybenzidine
3,3-Dihydroxybenzidine
3,3'-Dihydroxy-4,4'-diaminobiphenyl
4,4'-diaminobiphenyl-3,3'-diol
3,3'-Dwuoksybenzydyna
Benzidine, 3,3'-dihydroxy-
HSDB 4051
m,m'-Biphenol, 6,6'-diamino-
3,3'-Biphenyldiol, 4,4'-diamino-
CCRIS 9225
3,3'-Dwuoksybenzydyna [Polish]
OJ61P3RD7H
(1,1'-Biphenyl)-3,3'-diol, 4,4'-diamino-
BRN 2725972
[1,1'-Biphenyl]-3,3'-diol, 4,4'-diamino-
(1,1'-Biphenyl)-4,4'-diamine, 3,3'-dihydroxy-
DTXSID5025073
3-13-00-02309 (Beilstein Handbook Reference)
DIHYDROXYBENZIDINE, 3,3'-
3,3'-DIHYDROXYBENZIDINE [HSDB]
3,3'-DWUOKSYBENZYDYNA (POLISH)
[1,1'-BIPHENYL]-4,4'-DIAMINE, 3,3'-DIHYDROXY-
3,3'Dioxybenzidine
3,3'Dwuoksybenzydyna
Benzidine, 3,3'dihydroxy
m,m'Biphenol, 6,6'diamino
4,4'Diamino3,3'biphenyldiol
DTXCID805073
3,3'Biphenyldiol, 4,4'diamino
3,3'Dihydroxy4,4'diaminobiphenyl
6,6'-DIAMINO-M,M'-BIPHENOL
(1,1'Biphenyl)3,3'diol, 4,4'diamino
(1,1'Biphenyl)4,4'diamine, 3,3'dihydroxy
4,4'-DIAMINO-(1,1'-BI-PHENYL)-3,3'-DIOL
679-800-2
4,4'-Diamino-[1,1'-biphenyl]-3,3'-diol
2-amino-5-(4-amino-3-hydroxyphenyl)phenol
3,3'-Dihydroxy-4,4'-diamino-biphenyl
MFCD00039149
3,3'-Dihydroxybenzidine (HAB)
4,4'-Diamino-3,3'-dihydroxybiphenyl
UNII-OJ61P3RD7H
Benzidine-3,3'-diol
YSWG019
CHEMBL85811
SCHEMBL105866
ZGDMDBHLKNQPSD-UHFFFAOYSA-
AKOS015894243
3,3'-dihydroxy-4,4'-diamino-bipheny
CS-W014847
FD62618
SB79389
NCGC00091520-01
AC-22310
AS-11477
SY052119
4,4'-Diamino[1,1'-biphenyl]-3,3'-diol
D2312
NS00127178
D71200
4,4'-Diamino[1,1'-biphenyl]-3,3'-diol #
3,3 inverted exclamation mark -Dihydroxybenzidine
Q27285684
4,4'-Diamino[1,1'-biphenyl]-3,3'-diol, AldrichCPR
Benzidine-3,3'-diol;4,4'-Diamino-3,3'-dihydroxybiphenyl
InChI=1/C12H12N2O2/c13-9-3-1-7(5-11(9)15)8-2-4-10(14)12(16)6-8/h1-6,15-16H,13-14H2