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Sulfanilic acid

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Identification
Molecular formula
C6H7NO3S
CAS number
121-57-3
IUPAC name
2-amino-5-(4-aminophenyl)benzenesulfonic acid
State
State

At room temperature, sulfanilic acid is in a solid state, and it's typically provided in crystalline powder form. It is stable under normal temperatures and pressures.

Melting point (Celsius)
288.00
Melting point (Kelvin)
561.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
173.19g/mol
Molar mass
173.1860g/mol
Density
1.4850g/cm3
Appearence

Sulfanilic acid appears as a white to off-white crystalline powder. It may also form as crystalline flakes or sometimes as a paste, depending on its degree of hydration and formulation purity.

Comment on solubility

Solubility of 2-amino-5-(4-aminophenyl)benzenesulfonic acid

2-amino-5-(4-aminophenyl)benzenesulfonic acid, a sulfonic acid derivative, demonstrates interesting solubility properties in various solvents. Here are some key points regarding its solubility:

  • Water Solubility: This compound is highly soluble in water, primarily due to the presence of its sulfonic acid group, which enhances its ability to ionize and interact with water molecules.
  • Solvent Interaction: The amino groups in the structure may also form hydrogen bonds with water, further contributing to its solubility.
  • Additional Solvent Compatibility: It is often soluble in polar organic solvents, but its solubility decreases in non-polar solvents.

In general, the solubility characteristics of 2-amino-5-(4-aminophenyl)benzenesulfonic acid can be summarized as follows:

  1. Extremely soluble in water.
  2. Soluble in various polar organic solvents.
  3. Practically insoluble in non-polar solvents.

As with many compounds containing acidic and basic functional groups, the ionization and solubility can be influenced by changes in pH levels, making it essential to consider the environmental conditions during practical applications.

Interesting facts

Interesting Facts about 2-amino-5-(4-aminophenyl)benzenesulfonic acid

2-amino-5-(4-aminophenyl)benzenesulfonic acid, commonly known in the realms of chemistry and biochemistry for its role as a synthetic intermediate and reagent, has garnered attention for several fascinating reasons:

  • Versatile Applications: This compound serves as a key intermediate in the production of dyes and pigments. It can be modified to create various derivatives that exhibit distinct color properties, making it invaluable in the textile and plastics industries.
  • Pharmaceutical Relevance: Research has shown that certain derivatives of this sulfonic acid can exhibit biological activity, suggesting potential applications in drug discovery and development. Its structural components may have implications in antitumor and antimicrobial properties, opening avenues for medicinal chemistry.
  • Functional Groups Significance: The presence of both amino and sulfonic acid groups in this compound creates a highly polar structure, enhancing its solubility in water. This feature is crucial in reactions where aqueous solubility is a requisite.
  • Historical Context: Sulfonic acids have been used for over a century in the synthesis of various compounds. The historical contribution of compounds like 2-amino-5-(4-aminophenyl)benzenesulfonic acid to dye chemistry marks an essential chapter in industrial chemistry.

In summary, 2-amino-5-(4-aminophenyl)benzenesulfonic acid is not merely a compound of interest for its chemical properties but stands out as a milestone in both industrial applications and scientific research. As we explore the intricacies of this fascinating compound, we uncover the profound impact it has made across various fields.

Synonyms
2051-89-0
Benzidine-3-sulphuric acid
Benzidine, 3-sulfo-
Benzidine-3-sulfuric acid
[1,1'-Biphenyl]-3-sulfonic acid, 4,4'-diamino-
BRN 3532578
4,4'-diamino[1,1'-biphenyl]-3-sulphonic acid
2TT6WED8QF
EINECS 218-132-4
(1,1'-Biphenyl)-3-sulfonic acid, 4,4'-diamino-
4:4'-Diamino-3-diphenylyl hydrogen sulfate
4,4'-Diamino(1,1'-biphenyl)-3-sulphonic acid
BIPHENYL-3-SULFONIC ACID, 4,4'-DIAMINO-
DTXSID4062147
4-14-00-02806 (Beilstein Handbook Reference)
4,4'-Diamino[1,1'-biphenyl]-3-sulfonic acid
BIPHENYL-3-SULPHONIC ACID, 4,4'-DIAMINO-
4,4'-DIAMINO(1,1'-BIPHENYL)-3-SULFONIC ACID
4,4'-DIAMINO-(1,1'-BIPHENYL)-3-SULFONIC ACID
4,4'-DIAMINO-(1,1'-BIPHENYL)-3-SULPHONIC ACID
(1,1'-BIPHENYL)-3-SULPHONIC ACID, 4,4'-DIAMINO-
DTXCID7036327
218-132-4
2-amino-5-(4-aminophenyl)benzenesulfonic acid
UNII-2TT6WED8QF
benzidine-3-sulfonic acid
SCHEMBL866064
FGQDYDZVRHQDIN-UHFFFAOYSA-N
AKOS024336200
NS00026672