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Dapivirine

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Identification
Molecular formula
C15H14N6O
CAS number
244767-67-7
IUPAC name
2-amino-5-(aminomethyl)-1,7-dihydropyrrolo[2,3-d]pyrimidin-4-one
State
State

At room temperature, Dapivirine is a solid.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.15
Boiling point (Celsius)
644.80
Boiling point (Kelvin)
917.95
General information
Molecular weight
285.32g/mol
Molar mass
285.3290g/mol
Density
1.3900g/cm3
Appearence

The compound appears as a light yellow powder.

Comment on solubility

Solubility of 2-amino-5-(aminomethyl)-1,7-dihydropyrrolo[2,3-d]pyrimidin-4-one

The solubility of 2-amino-5-(aminomethyl)-1,7-dihydropyrrolo[2,3-d]pyrimidin-4-one (C15H14N6O) exhibits notable characteristics due to its complex molecular structure.

Considering its molecular composition, the solubility can be summarized as follows:

  • Polar Nature: The presence of amino groups contributes to a polar character, enhancing solubility in polar solvents such as water.
  • Hydrogen Bonding: This compound can form hydrogen bonds, which facilitates its interaction with water molecules, further improving solubility.
  • Solvent Dependency: Solubility may vary significantly depending on the solvent used; it is expected to be more soluble in protic solvents compared to aprotic solvents.
  • Concentration Limits: In practical applications, concentration limits may arise; thus, it is crucial to assess solubility under various conditions to determine operational feasibilities.

In conclusion, while this compound exhibits solubility in polar environments, it is crucial to conduct empirical assessments to establish precise solubility data under varying conditions, enhancing understanding for practical applications.

Interesting facts

Interesting Facts about 2-Amino-5-(aminomethyl)-1,7-dihydropyrrolo[2,3-d]pyrimidin-4-one

This compound is a fascinating member of the pyrrolo-pyrimidine family, characterized by its unique structural features and promising biological activities. Here are some intriguing insights:

  • Medicinal Potential: The intricate arrangement of nitrogen atoms in the structure gives it possible therapeutic applications, particularly in the field of cancer research, as it may interact with key biomolecular targets.
  • Synthetic Route: The synthesis of this compound emphasizes the significance of multi-step organic synthesis, utilizing various reactions that require precision and creativity from chemists to construct the pyrrolo-pyrimidine skeleton.
  • Diverse Biological Activities: Research indicates that compounds with similar structures often exhibit antifungal, antibacterial, and anti-inflammatory properties, making them valuable in medical chemistry.
  • Research Interest: Given its complex structure and biological importance, it continues to attract research attention, with scientists exploring its mechanisms of action as well as its potential as a drug candidate.

In summary, 2-amino-5-(aminomethyl)-1,7-dihydropyrrolo[2,3-d]pyrimidin-4-one is a noteworthy compound that showcases the intersection of organic chemistry and medicinal science. As the quest for new therapeutics continues, particularly in the age of personalized medicine, this compound may play a role in innovative drug development.