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2-Amino-5-chloro-1,3-benzoxazol-6-ol

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Identification
Molecular formula
C7H5ClN2O2
CAS number
17852-52-7
IUPAC name
2-amino-5-chloro-1,3-benzoxazol-6-ol
State
State

At room temperature, 2-Amino-5-chloro-1,3-benzoxazol-6-ol is in a solid state. It is generally stable under normal conditions but should be kept in a dry, cool place to maintain its integrity.

Melting point (Celsius)
309.00
Melting point (Kelvin)
582.15
Boiling point (Celsius)
462.00
Boiling point (Kelvin)
735.15
General information
Molecular weight
184.57g/mol
Molar mass
184.5700g/mol
Density
1.5400g/cm3
Appearence

2-Amino-5-chloro-1,3-benzoxazol-6-ol typically appears as a white to off-white crystalline powder. Its precise appearance can vary slightly depending on purity and specific form.

Comment on solubility

Solubility of 2-amino-5-chloro-1,3-benzoxazol-6-ol

When discussing the solubility of 2-amino-5-chloro-1,3-benzoxazol-6-ol, several key factors come into play:

  • Polarity: The presence of both amino and hydroxyl groups contributes to the polar nature of this compound, enhancing its potential for solubility in polar solvents.
  • Solvent Interaction: Generally, compounds with similar polarity to the solvent tend to dissolve better. As a result, 2-amino-5-chloro-1,3-benzoxazol-6-ol may exhibit good solubility in water and alcohols due to hydrogen bonding capabilities.
  • Hydrogen Bonding: The ability of the -OH and -NH2 groups to form hydrogen bonds with water molecules plays a vital role in determining the solubility. This can lead to increased solubility in aqueous and organic polar solvents.

However, it is important to note that specific solubility values can vary based on experimental conditions such as temperature and concentration. In some cases, the compound may present limited solubility in non-polar solvents, indicating that it prefers environments that allow for these polar interactions to take place.

In summary, the solubility of 2-amino-5-chloro-1,3-benzoxazol-6-ol is heavily influenced by:

  1. Its polar functional groups.
  2. The solvent characteristics.
  3. The formation of hydrogen bonds.

Thus, the compound is likely to demonstrate good solubility in polar solvents, making it versatile in various applications.

Interesting facts

Interesting Facts about 2-Amino-5-chloro-1,3-benzoxazol-6-ol

2-Amino-5-chloro-1,3-benzoxazol-6-ol is a fascinating compound that has garnered interest in both research and industrial applications. Here are some key points that highlight its significance:

  • Pharmaceutical Potential: This compound showcases potential as a precursor in the synthesis of various medicinal agents. Its unique structure opens avenues for creating targeted therapies in treating diseases.
  • Structure-Activity Relationship (SAR): The presence of amino and chloro groups plays a critical role in the compound’s reactivity and interaction with biological systems, making it a valuable subject of study in medicinal chemistry.
  • Fluorescent Properties: Compounds similar to 2-amino-5-chloro-1,3-benzoxazol-6-ol are known to exhibit interesting fluorescent characteristics, which can be harnessed in biochemical assays and imaging techniques.
  • Synthetic Versatility: The synthetic routes to obtain this compound may include various strategies such as cyclization reactions and functional group transformations, showcasing the complexity and creativity involved in modern organic synthesis.
  • Environmental Considerations: As with many halogenated compounds, the environmental impact and degradation pathways of 2-amino-5-chloro-1,3-benzoxazol-6-ol are important considerations in the field of green chemistry, prompting ongoing research into minimizing harmful effects.

In summary, 2-amino-5-chloro-1,3-benzoxazol-6-ol is more than just a compound; it represents a combination of intriguing chemical properties and potential applications that continue to inspire researchers in the field of chemistry.

Synonyms
1750-46-5
BENZOXAZOLE, 2-AMINO-5-CHLORO-6-HYDROXY-
NSC 24956
2-Amino-5-chloro-6-hydroxybenzoxazole
BRN 0909558
DTXSID60169920
DTXCID4092411
6-Benzoxazolol, 2-amino-5-chloro-(8CI)
6-Benzoxazolol, 2-amino-5-chloro-(8CI)(9CI)
2-amino-5-chloro-1,3-benzoxazol-6-ol
6-Benzoxazolol, 2-amino-5-chloro-
NSC24956
NSC-24956
WLN: T56 BN DOJ CZ GQ HG