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2-Amino-5-chlorobenzoic acid

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Identification
Molecular formula
C7H6ClNO2
CAS number
635-21-0
IUPAC name
2-amino-5-chloro-benzoic acid
State
State

At room temperature, 2-Amino-5-chlorobenzoic acid is typically in a solid state. It exists in a stable crystalline form and does not transition to other states without significant changes in temperature or pressure.

Melting point (Celsius)
278.00
Melting point (Kelvin)
551.15
Boiling point (Celsius)
276.00
Boiling point (Kelvin)
549.15
General information
Molecular weight
171.59g/mol
Molar mass
171.5750g/mol
Density
1.5780g/cm3
Appearence

2-Amino-5-chlorobenzoic acid appears as a white to off-white crystalline powder. It is typically odorless and has a rough crystalline texture. The color may vary slightly depending on the purity and exact form of the sample.

Comment on solubility

Solubility of 2-amino-5-chloro-benzoic acid

2-amino-5-chloro-benzoic acid, with the chemical formula C7H6ClN1O2, exhibits some interesting solubility characteristics that are essential to understand its behavior in various environments. Here are some key points regarding its solubility:

  • Water Solubility: This compound is moderately soluble in water, which can be attributed to the presence of both amino and carboxylic acid functional groups that can form hydrogen bonds with water molecules.
  • Solvent Dependence: The solubility tends to vary significantly with the choice of solvent. For instance, it is more soluble in polar solvents compared to non-polar solvents.
  • pH Influence: The solubility can also be affected by pH levels. In more acidic environments, the carboxylic acid group may remain protonated, while in neutral to basic conditions, it can deprotonate, enhancing solubility.
  • Temperature Effect: Increasing the temperature usually improves the solubility of many organic compounds, including 2-amino-5-chloro-benzoic acid.

Overall, understanding the solubility of 2-amino-5-chloro-benzoic acid is crucial for its applications in pharmaceuticals and chemical industries, where its reactivity and solubility behavior greatly influence its utility.

Interesting facts

Interesting Facts about 2-amino-5-chloro-benzoic acid

2-amino-5-chloro-benzoic acid, commonly known as 5-Chloroanthranilic acid, is a fascinating organic compound with significant relevance in various fields of chemistry and biology.

Chemical Structure and Properties

This compound features a benzene ring substituted with an amino group and a chloro group, making it an intriguing member of the amino benzoic acids family. The dual functionality of the amino and chloro groups contributes to its unique reactivity and versatility in synthesis.

Applications

2-amino-5-chloro-benzoic acid has diverse applications, including:

  • Dyes and Pigments: It plays a crucial role in the synthesis of azo dyes, which are widely used in textiles.
  • Pharmaceuticals: This compound has shown potential as an intermediate in the production of various pharmaceutical agents, owing to its bioactive properties.
  • Research: It is utilized in biological research to study its effects on metabolic pathways and enzyme activity.

Biological Significance

In the realm of pharmacology, compounds similar to 2-amino-5-chloro-benzoic acid have been investigated for their roles in:

  • Anti-inflammatory Effects: Research suggests that analogs may exert anti-inflammatory properties, which can be valuable in therapeutic applications.
  • Antimicrobial Activities: Such compounds often display antimicrobial properties, making them relevant in drug development.

Quotable Insight

As noted in many scientific studies, “Understanding the reactivity of halogenated amino acids can lead to breakthroughs in drug discovery and material science.” This highlights the ongoing importance of compounds like 2-amino-5-chloro-benzoic acid in advancing both fundamental and applied chemistry.

In summary, 2-amino-5-chloro-benzoic acid is not just a simple organic compound but a significant molecule with potential applications in numerous scientific fields, paving the way for innovative research and development.

Synonyms
2-AMINO-5-CHLOROBENZOIC ACID
635-21-2
5-Chloroanthranilic acid
Benzoic acid, 2-amino-5-chloro-
5-Chloro-2-aminobenzoic acid
Anthranilic acid, 5-chloro-
2-carboxy-4-chloroaniline
UNII-Z2Y66JMI31
Z2Y66JMI31
EINECS 211-230-8
NSC 404157
NSC-404157
AI3-15229
DTXSID8060901
CHEBI:166853
5Chloroanthranilic acid
5Chloro2aminobenzoic acid
Anthranilic acid, 5chloro
Benzoic acid, 2amino5chloro
DTXCID9043938
Anthranilic acid, 5chloro (8CI)
Anthranilic acid, 5-chloro-(8CI)
ifxkxclvkqvvdi-uhfffaoysa-n
inchi=1/c7h6clno2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3h,9h2,(h,10,11
MFCD00007838
2-Amino-5-chloro-benzoic acid
CHEMBL36767
2-Amino-5-chlorobenzoicacid
5-amino-3-carboxy-1-chlorobenzene
2-Amino-5-chlorobenzoic Acid; 2-Carboxy-4-chloroaniline; 5-Chloro-2-aminobenzoic Acid; NSC 404157;
2-amino 5-chlorobenzoic acid
SCHEMBL220073
2-Amino-5-chloro benzoic acid
5-chloro-2-amino-benzoic acid
2-Aminobenzoic acid, 5-chloro-
BDBM50122010
NSC404157
STL193534
2-Amino-5-chlorobenzoic acid, 98%
AKOS000120636
AC-2483
CS-W020077
FA00600
PS-4469
BP-20250
PD055551
SY001607
DB-020465
A0665
NS00035485
EN300-20971
AE-562/40238138
2-Amino-5-chlorobenzoic acid, 90%, technical grade
Q27294923
F1943-0104
Z104485568