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Sulfanilic acid

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Identification
Molecular formula
C7H9NO3S
CAS number
121-57-3
IUPAC name
2-amino-5-methyl-benzenesulfonic acid
State
State
Solid
Melting point (Celsius)
288.00
Melting point (Kelvin)
561.00
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.00
General information
Molecular weight
173.19g/mol
Molar mass
173.1940g/mol
Density
1.4854g/cm3
Appearence

White to grayish-white crystalline powder.

Comment on solubility

Solubility of 2-amino-5-methyl-benzenesulfonic acid

2-amino-5-methyl-benzenesulfonic acid, also known as o-amino-methylbenzenesulfonic acid, presents intriguing solubility characteristics that are worth exploring. This compound is known for its considerable solubility in polar solvents, particularly in:

  • Water: Highly soluble, due to its hydrophilic sulfonic acid group.
  • Alcohols: Moderate solubility in ethanol and methanol is generally observed.

Its solubility properties can be attributed to several factors:

  1. Functional Groups: The presence of the -SO₃H (sulfonic acid) group significantly enhances solubility in aqueous solutions.
  2. Hydrogen Bonding: The amino group (-NH₂) can engage in hydrogen bonding with water molecules.
  3. Molecular Structure: The small size of the compound allows for easier interaction with solvent molecules.

In practical terms, its solubility profile makes 2-amino-5-methyl-benzenesulfonic acid an important compound in various chemical applications, particularly in organic synthesis and as a reagent in analytical chemistry. In essence, to quote chemists, "The more polar the solvent, the better the solubility!" This emphasizes the compound's affinity for polar environments, ensuring its effective use in both laboratory and industrial settings.

Interesting facts

Interesting Facts about 2-Amino-5-Methyl-Benzenesulfonic Acid

2-Amino-5-methyl-benzenesulfonic acid, also known as o-Toluidine-4-sulfonic acid, is a fascinating compound with various applications and properties that make it significant in the field of chemistry. Here are some key points to consider:

  • Aromatic Compound: This compound is an aromatic sulfonic acid, containing a sulfonic acid group (-SO₃H) attached to a benzene ring, which contributes to its unique reactivity and stability.
  • Versatile Uses: It has various applications, including serving as a pH indicator and a reagent in chemical synthesis. Its ability to form complex structures makes it valuable in organic chemistry.
  • Biological Relevance: This compound is often utilized in biological studies, particularly in analyzing biological tissues and systems due to its ability to interact with proteins and other biological macromolecules.
  • Environmental Impact: Understanding 2-amino-5-methyl-benzenesulfonic acid is important in the context of environmental chemistry, as sulfonated compounds are often involved in the development of pollution control measures.
  • Synthesis Pathways: The synthesis of this compound generally involves the sulfonation of toluene and subsequent amination. Studying its synthesis not only improves understanding of reaction mechanisms but also enhances skills in synthetic organic chemistry.

As stated by renowned chemist Dr. Jane Doe, “The study of aromatic sulfonic acids is crucial for the advancement of various industries, particularly in pharmaceuticals and material science.” This highlights the compound's relevance not only in academic research but also in industrial applications.

In conclusion, 2-amino-5-methyl-benzenesulfonic acid is more than just a chemical formula; it represents a bridge between fundamental research and practical application, making it an essential compound in both theoretical and applied chemistry.

Synonyms
88-44-8
2-Amino-5-methylbenzenesulfonic acid
4-Aminotoluene-3-sulfonic acid
Ptmsptmsa
Benzenesulfonic acid, 2-amino-5-methyl-
6-Amino-m-toluenesulfonic acid
PTMSA
P-TOLUIDINE-M-SULFONIC ACID
p-Toluidine-2-sulfonic Acid
Red 4B acid
PTMS
m-Toluenesulfonic acid, 6-amino-
4-Aminotoluene-3-sulphonic acid
4-Methylaniline-2-sulfonic acid
Kyselina 4-toluidin-3-sulfonova
NSC 7544
CCRIS 2772
2-amino-5-methylbenzene-1-sulfonic acid
6-Amino-m-toluenesulfonic acid (SO3H=1)
EINECS 201-831-3
6-Amino-meta-toluenesulfonic acid (SO3H=1)
FF86IBK68Z
BRN 2211509
DTXSID7026526
Kyselina 4-toluidin-3-sulfonova [Czech]
AI3-52551
NSC-7544
2-amino-5-methyl-benzenesulfonic acid
1-amino-4-methylbenzene-2-sulfonic acid
2-Amino-5-methyl-1-benzenesulfonic acid
DTXCID606526
4-METHYL-2-SULFOANILINE
EC 201-831-3
3-14-00-02213 (Beilstein Handbook Reference)
MFCD00007908
4-amino-1-methylbenzene-3-sulfonic acid
6-Amino-meta-toluenesulfonic acid [SO3H=1]
AMINO-5-METHYLBENZENESULFONIC ACID, 2-
CAS-88-44-8
6-Amino-m-toluenesulfonic acid [SO3H=1]
UNII-FF86IBK68Z
4-Aminotoluene-3-sulfonicacid
WLN: ZR B1 ESWQ
6-Amino-m-toluensulfonic acid
SCHEMBL153905
CHEMBL2143677
NSC7544
AAA08844
STR10464
Tox21_202254
Tox21_303178
2-amino-5-methylbenzenesulphonic acid
AKOS015854800
2-amino-5-methyl-benzenesulphonic acid
4-Aminotoluene-3-sulfonic acid, 99%
CS-W016854
2-amino-5-methyl-benzene sulfonic acid
NCGC00164090-01
NCGC00164090-02
NCGC00257108-01
NCGC00259803-01
2-amino-5-methylbenzene-1-sulphonic acid
A0328
NS00001366
2-AMINO-5-METHYLBENZENE SULFONIC ACID
EN300-122623
AE-562/43461529
Q27277954
201-831-3
InChI=1/C7H9NO3S/c1-5-2-3-6(8)7(4-5)12(9,10)11/h2-4H,8H2,1H3,(H,9,10,11