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2-Amino-5-nitrobenzoic acid

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Identification
Molecular formula
C7H6N2O4
CAS number
94-16-6
IUPAC name
2-amino-5-nitro-benzoic acid
State
State

At room temperature, 2-amino-5-nitrobenzoic acid is typically a solid. It is often handled as a powder, which should be stored in a cool, dry place to maintain its stability.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
528.85
Boiling point (Kelvin)
802.00
General information
Molecular weight
182.14g/mol
Molar mass
182.1440g/mol
Density
1.6132g/cm3
Appearence

2-Amino-5-nitrobenzoic acid appears as a pale yellow crystalline powder. The solid is fine and features a distinct yellowish tint due to the presence of the nitro group in its structure.

Comment on solubility

Solubility of 2-amino-5-nitro-benzoic acid

2-amino-5-nitro-benzoic acid (C7H6N2O4) exhibits interesting solubility characteristics, which can be valuable in various applications. Here are some key points regarding its solubility:

  • Polarity: This compound contains both amino (–NH2) and nitro (–NO2) groups, which contribute to its polarity. The presence of these polar functional groups enhances its solubility in polar solvents.
  • Solvent Compatibility: 2-amino-5-nitro-benzoic acid is more soluble in water as compared to many non-polar solvents. It may also dissolve in other polar solvents such as methanol and ethanol.
  • Temperature Dependence: Its solubility tends to increase with temperature, which is a common characteristic for many organic acids.
  • pH Effect: The solubility can also be affected by the pH of the solution. Under acidic conditions, the compound remains in its molecular form, potentially increasing solubility, while at higher pH levels, it may exist more as a salt, also influencing its solubility dynamics.

Overall, the solubility of 2-amino-5-nitro-benzoic acid is dictated by its molecular structure and environmental conditions, making it suitable for a variety of chemical processes. Its polar nature, coupled with functional group interactions, underscores its significance in synthetic and analytical chemistry.

Interesting facts

Interesting Facts about 2-amino-5-nitro-benzoic acid

2-amino-5-nitro-benzoic acid, commonly referred to as 5-nitro-2-aminobenzoic acid, is a fascinating compound that belongs to the class of aminobenzoic acids. This compound presents a unique structure that allows it to play significant roles in various applications. Here are some intriguing aspects:

  • Dual Functional Groups: The presence of both an amino group (–NH2) and a nitro group (–NO2) in its structure makes it a versatile molecule. These groups can participate in various chemical reactions, promoting its utility in synthetic organic chemistry.
  • Pharmaceutical Applications: Due to its structure, 2-amino-5-nitro-benzoic acid is often found in studies relating to anti-inflammatory and analgesic agents. Researchers are continually exploring its potential as a precursor for synthesizing other biologically active compounds.
  • Colorimetric Assays: This compound is also utilized in colorimetric assays due to its distinct absorption characteristics. The nitro group in the molecule contributes to its ability to act as a chromophore, making it useful in analytical chemistry.
  • Environmental Impact: As a nitro-substituted compound, it is essential to consider the environmental effects of 2-amino-5-nitro-benzoic acid, especially in its degradation products. Understanding how it behaves in natural ecosystems is crucial for evaluating its safety profile.
  • Synthetic Routes: Chemists have developed various synthetic pathways to produce this compound, including nitration of amino-substituted benzoic acids. Exploring these routes can offer insights into reaction mechanisms and the stability of functional groups.

Overall, 2-amino-5-nitro-benzoic acid stands out not only for its unique chemical properties but also for its vast implications in chemical research and industrial applications. As scientists continue to investigate its capabilities, this compound may unveil even more fascinating facets in the world of chemistry.

Synonyms
2-AMINO-5-NITROBENZOIC ACID
616-79-5
5-Nitroanthranilic acid
Benzoic acid, 2-amino-5-nitro-
Anthranilic acid, 5-nitro-
1-amino-2-carboxy-4-nitrobenzene
CHEBI:61280
5-Nitroantranilic acid
EINECS 210-493-6
NSC 16208
NSC 63867
DTXSID8060668
DTXCID2043086
Anthranilic acid, 5-nitro-(8CI)
210-493-6
inchi=1/c7h6n2o4/c8-6-2-1-4(9(12)13)3-5(6)7(10)11/h1-3h,8h2,(h,10,11
ruchwtkmowxhlu-uhfffaoysa-n
2-Amino-5-nitro-benzoic acid
5NAA
MFCD00017039
2-Amino-5-nitrobenzoicacid
5-nitro-anthranilic acid
Cambridge id 5161184
NCIOpen2_000213
CHEMBL39476
SCHEMBL377824
2-azanyl-5-nitro-benzoic acid
BCP19327
HY-Y1681
NSC16208
NSC63867
STR03468
2-Amino-5-nitrobenzoic acid, 95%
BBL000333
NSC-16208
NSC-63867
STK267557
AKOS000120536
AKOS040744422
AC-7405
CS-W020043
FA38393
NCGC00336357-01
BP-20119
SY006070
DB-024171
N0644
NS00034763
EN300-17935
C19788
N60015
AB01330342-02
AG-205/04762061
Q27130976
Z57124408
F0211-0001
6R6