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Folinic acid

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Identification
Molecular formula
C20H23N7O6P
CAS number
58-05-9
IUPAC name
2-amino-6-[hydroxy-(5-hydroxy-2-oxido-2-oxo-1,3,2lambda5-dioxaphosphinan-4-yl)methyl]-4a,5,8,8a-tetrahydro-3H-pteridin-4-one
State
State

Folinic acid is typically in a solid state at room temperature, appearing as a fine powder. It is used in its solid form for various pharmaceutical applications.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.00
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.00
General information
Molecular weight
474.43g/mol
Molar mass
474.4320g/mol
Density
2.2900g/cm3
Appearence

Folinic acid is typically a white to off-white crystalline powder. It is odorless and is freely soluble in water, practically insoluble in alcohols, and insoluble in organic solvents.

Comment on solubility

Solubility of 2-amino-6-[hydroxy-(5-hydroxy-2-oxido-2-oxo-1,3,2lambda5-dioxaphosphinan-4-yl)methyl]-4a,5,8,8a-tetrahydro-3H-pteridin-4-one

The solubility of the compound 2-amino-6-[hydroxy-(5-hydroxy-2-oxido-2-oxo-1,3,2lambda5-dioxaphosphinan-4-yl)methyl]-4a,5,8,8a-tetrahydro-3H-pteridin-4-one (C20H23N7O6P) is influenced by its complex structure and the presence of functional groups. Understanding its solubility characteristics can provide insight into its potential applications and behavior in various environments.

Key Factors Affecting Solubility:

  • Polarity: The presence of multiple hydroxyl (–OH) and amino (–NH2) groups increases the polarity of the compound, which generally enhances solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds due to its functional groups further facilitates solvation, thereby improving its solubility in aqueous environments.
  • pH Dependency: The solubility may vary with pH changes, since the ionization of amino and hydroxyl groups can affect the compound's interaction with solvents.

Solubility Insights:

Due to its complex molecular architecture, the solubility of this compound can be predicted to:

  • Be relatively high in polar solvents compared to non-polar solvents.
  • Exhibit variable solubility depending on the specific conditions of the environment (e.g., temperature, pH).

As a result, it is crucial to conduct empirical solubility tests to ascertain its actual behavior in different solvents, particularly in formulations relevant for pharmaceutical or biochemical applications.

Interesting facts

Exploring 2-amino-6-[hydroxy-(5-hydroxy-2-oxido-2-oxo-1,3,2lambda5-dioxaphosphinan-4-yl)methyl]-4a,5,8,8a-tetrahydro-3H-pteridin-4-one

This complex compound is an intriguing example of how the intricate world of chemistry can fuse together structural diversity and functional relevance. Known for its multifaceted structure, it encompasses a range of elements and functional groups that contribute to its unique properties and potential applications.

Key Features:

  • Biological Relevance: This compound is a potential candidate in pharmacological studies due to its pteridin backbone, which is often associated with important biological activities.
  • Pharmaceutical Potential: It suggests utility in drug development, particularly as a ligand in enzyme inhibition, owing to its diverse functional groups.
  • Catalytic Activity: The presence of phosphorus in its structure signifies potential for catalytic applications in various chemical reactions.

Moreover, the compound includes a dioxaphosphinan ring, which is a noteworthy feature that often enhances stability and reactivity in organic synthesis. As a scientist, one might quote a famous chemist observing the elegance of such compounds: “In the realm of chemistry, the beauty lies not just in structure, but in the possibility of transformation.”

Potential Research Avenues:

  • Investigating its role in medicinal chemistry.
  • Studying its interactions with biological macromolecules.
  • Exploring its environmental impact and degradation pathways.

Overall, 2-amino-6-[hydroxy-(5-hydroxy-2-oxido-2-oxo-1,3,2lambda5-dioxaphosphinan-4-yl)methyl]-4a,5,8,8a-tetrahydro-3H-pteridin-4-one exemplifies the fascinating interplay between chemical structure and biological function, making it a rich subject for ongoing research and discovery!