Cordycepin | Solubility of Things

Identification

Molecular formula

C₁₀H₁₃N₅O₃

CAS number

73-03-0

IUPAC name

2-amino-7-[3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one

State

At room temperature, cordycepin is typically found as a solid.

Melting point (Celsius)

171.00

Melting point (Kelvin)

444.20

Boiling point (Celsius)

385.50

Boiling point (Kelvin)

658.70

General information

Molecular weight

251.24g/mol

Molar mass

252.2450g/mol

Density

1.9980g/cm³

Appearence

White or off-white crystalline powder.

Comment on solubility

Solubility of 2-amino-7-[3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one

The solubility of the compound 2-amino-7-[3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one (C₁₀H₁₃N₅O₃) is an important characteristic to consider in its chemical behavior and application. Here are some key aspects regarding its solubility:

Polarity: The presence of multiple hydroxyl (-OH) groups in the molecular structure significantly increases the polarity of the compound, suggesting that it may be more soluble in polar solvents, such as water.
Hydrogen Bonding: The ability to form hydrogen bonds due to its amino and hydroxyl groups enhances its solubility in aqueous environments.
Hydrolytic Stability: Given the structural complexity and potential for hydrolysis, the solubility may vary based on pH and the presence of other solutes.
Temperature Dependency: It is likely that the solubility increases with temperature, as is common for many organic compounds.

In conclusion, while the precise solubility value of this compound may require experimental determination, it is reasonable to predict that its solubility in water is relatively high due to its polar characteristics and the potential for hydrogen bonding. Understanding these solubility properties is crucial for its effective use in pharmaceutical formulations and other chemical applications.

Interesting facts

Interesting Facts about 2-amino-7-[3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one

This complex compound, often referred to in the scientific community as a member of the pyrrolidinyl-pyrimidine family, has fascinated chemists due to its intriguing structure and potential biological applications. Here are some engaging details regarding this particular compound:

Biological Interest: The structure features several functional groups that may play significant roles in biological activities, making it a candidate for pharmaceutical research.
Binding Affinity: Its unique configuration allows it to potentially interact with biological targets, such as enzymes or receptors, which could influence metabolic pathways.
Potential Therapeutic Uses: Compounds with similar structures have been studied for their effects in areas such as cancer therapy or neurological disorders, highlighting the need for ongoing research.
Synthetic Challenges: The synthesis of this compound involves multiple steps, including the construction of the pyrrolidinyl ring, which can require advanced chemical techniques and expertise.
Structure-Activity Relationship (SAR): Understanding how changes in its chemical structure influence its biological properties is crucial. It offers a fertile ground for SAR studies in medicinal chemistry.

As a student or researcher, appreciating the nuances of such a compound can fuel curiosity and innovation in drug development and molecular biology. The intersection of chemical structure and biological function is at the heart of much scientific inquiry, making compounds like this an exciting area of study.

In the words of a famous scientist, "The beauty of chemical substances lies in their complexity and the potential they hold for discovering new therapies." As this compound illustrates, the world of chemistry is rich with possibilities waiting to be explored!