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Antipyrine

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Identification
Molecular formula
C11H12N2O
CAS number
60-80-0
IUPAC name
2-amino-N-(1,5,6-trihydroxy-3-methyl-8-oxo-3,4,4a,5,6,7-hexahydroisochromen-4-yl)propanamide
State
State

The compound is a solid at room temperature, and it usually forms in a stable, crystalline condition.

Melting point (Celsius)
113.00
Melting point (Kelvin)
386.15
Boiling point (Celsius)
418.00
Boiling point (Kelvin)
691.15
General information
Molecular weight
188.23g/mol
Molar mass
188.2280g/mol
Density
1.2820g/cm3
Appearence

Antipyrine typically appears as a white crystalline powder. It is odourless and has a distinct crystalline structure. When exposed to air, it remains stable and does not absorb moisture easily, preserving its crystalline appearance over time.

Comment on solubility

Solubility of 2-amino-N-(1,5,6-trihydroxy-3-methyl-8-oxo-3,4,4a,5,6,7-hexahydroisochromen-4-yl)propanamide

The solubility of 2-amino-N-(1,5,6-trihydroxy-3-methyl-8-oxo-3,4,4a,5,6,7-hexahydroisochromen-4-yl)propanamide is influenced by various factors, including its molecular structure and the functional groups present. Here are some key points regarding its solubility:

  • Hydrophilicity: The presence of multiple hydroxyl (-OH) groups contributes to its hydrophilic nature, which may enhance solubility in polar solvents like water.
  • Hydrophobic Regions: The hexahydroisochromene structure contains hydrophobic portions, which may limit its solubility in solely aqueous environments.
  • Interactions: The ability to form hydrogen bonds due to the amino and hydroxyl groups can significantly affect solubility, often favoring dissolution in organic solvents that can engage in such interactions.
  • pH Dependence: The solubility may vary with changes in pH, particularly due to the amino group, which can accept protons and become positively charged, potentially altering solubility characteristics.

In summary, the solubility of this compound is likely to be >em>moderate in polar solvents, yet it may encounter challenges in fully aqueous systems due to its complex structure that offers both hydrophilic and hydrophobic characteristics.

Interesting facts

Interesting Facts about 2-amino-N-(1,5,6-trihydroxy-3-methyl-8-oxo-3,4,4a,5,6,7-hexahydroisochromen-4-yl)propanamide

This complex compound, derived from a family of isochromen derivatives, showcases a blend of intriguing structural features that have drawn the attention of chemists and pharmacologists alike. Here are some fascinating aspects of this compound:

  • Bioactive Potential: The intricate structure of this compound hints at various potential biological activities, possibly serving as a framework for the development of new therapeutic agents.
  • Structural Diversity: The presence of multiple hydroxyl groups and an amide functional group contributes to its potential reactivity and ability to form hydrogen bonds, a vital factor in molecular interactions.
  • Synthetic Challenges: The synthesis of this compound might pose significant challenges, especially in terms of controlling stereochemistry and functional group transformations.
  • Isochromen Moiety: The isochromen core is known for its occurrence in many natural products and medicines, suggesting that this compound could mimic or enhance similar physiological effects.
  • Pharmaceutical Applications: Compounds with similar structures have been explored for their roles in treating various diseases, including cancer and inflammation, indicating potential pathways for research and application.

One quote from a renowned chemist puts it best: "The beauty of chemistry lies in its ability to combine simplicity and complexity in ways that nature can use." This compound exemplifies that sentiment perfectly.

Additionally, exploring its potential derivatives may reveal even more about its functional capabilities, bridging knowledge between synthetic chemistry and medicinal science.