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Glycine

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Identification
Molecular formula
C2H5NO2
CAS number
56-40-6
IUPAC name
2-aminoacetic acid
State
State

Glycine is typically found in a solid state at room temperature.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
233.00
Boiling point (Kelvin)
506.15
General information
Molecular weight
75.07g/mol
Molar mass
75.0670g/mol
Density
1.6070g/cm3
Appearence

Glycine appears as a white crystalline solid. It is typically found as a powder. The crystals tend to have a slightly sweet taste.

Comment on solubility

Solubility of 2-aminoacetic acid (C2H5NO2)

2-aminoacetic acid, commonly known as glycine, exhibits remarkable solubility characteristics that make it an intriguing compound in the realm of chemistry. Its solubility can be summarized as follows:

  • Water Solubility: Glycine is highly soluble in water, with a solubility of approximately 100g per liter at room temperature. This property is primarily due to its ability to form hydrogen bonds with water molecules.
  • Organic Solvents: Glycine has limited solubility in organic solvents such as ethanol and acetone, which is indicative of its polar nature.
  • pH Influence: The solubility of glycine is significantly affected by the pH of the solution. In acidic conditions, it exists in its protonated form, whereas in basic conditions, it exists as a deprotonated anion. This characteristic allows glycine to exhibit variable solubility depending on the environmental pH.

It's noteworthy that glycine's solubility is not just a matter of quantity; it plays a critical role in various biological processes and applications. In summary, 2-aminoacetic acid’s solubility properties make it a vital compound for many scientific inquiries and applications, maintaining its position as an essential amino acid.

Interesting facts

Interesting Facts About 2-Aminoacetic Acid

2-Aminoacetic acid, commonly known as Glycine, is the simplest amino acid and plays a crucial role in biochemistry. Here are some fascinating aspects of this essential compound:

  • Building Block of Proteins: Glycine is one of the 20 standard amino acids used by cells to synthesize proteins. Its small size allows it to fit into tight spaces within protein structures, which is vital for their flexibility and function.
  • Neurotransmitter Role: It serves as an important neurotransmitter in the central nervous system, exerting inhibitory effects that help regulate neural activity.
  • Presence in Nature: Glycine is found abundantly in nature, occurring naturally in various proteins and is particularly high in collagen, which is a major component of connective tissues.
  • Manufacturing Uses: In industry, glycine is utilized in the production of various biochemical products, including sweeteners, and it also serves as a buffering agent in pharmaceuticals.

Health Benefits

Beyond its biochemical importance, glycine offers several health benefits:

  • Sleep Aid: Some studies suggest that glycine may improve sleep quality. It can promote feelings of calmness and help lower body temperature, facilitating better sleep.
  • Muscle Regeneration: It plays a role in muscle repair and growth, particularly after injury or intense exercise, making it beneficial for athletes.
  • Antioxidant Properties: Glycine may serve as a precursor for glutathione, a potent antioxidant that protects cells from oxidative damage.

In conclusion, 2-aminoacetic acid is more than just a simple amino acid; it is fundamental to biological processes and possesses numerous practical applications for health and industry. As a versatile compound, it continues to be a subject of extensive study and holds promise for future therapeutic interventions.

Synonyms
glycine
56-40-6
2-Aminoacetic acid
aminoacetic acid
Glycocoll
Aminoethanoic acid
Glycolixir
H-Gly-OH
Glicoamin
Glycosthene
Aciport
Padil
Hampshire glycine
L-Glycine
Amitone
Leimzucker
Aminoazijnzuur
Acetic acid, amino-
Glycine, non-medical
Sucre de gelatine
Glicina
Glycinum
GLY (IUPAC abbrev)
Gyn-hydralin
Corilin
Glycine [INN]
Glyzin
FEMA No. 3287
Acido aminoacetico
Glycinum [INN-Latin]
Acide aminoacetique
Glicina [INN-Spanish]
Acidum aminoaceticum
gly
Glykokoll
Aminoessigsaeure
Hgly
CCRIS 5915
HSDB 495
Acide aminoacetique [INN-French]
Acido aminoacetico [INN-Spanish]
Acidum aminoaceticum [INN-Latin]
25718-94-9
AI3-04085
MFCD00008131
NSC 25936
GLYCINE 1.5% IN PLASTIC CONTAINER
H2N-CH2-COOH
amino-Acetic acid
EINECS 200-272-2
UNII-TE7660XO1C
NSC-25936
[14C]glycine
TE7660XO1C
DTXSID9020667
CHEBI:15428
Glycine [USP:INN]
NSC25936
CHEMBL773
DTXCID90667
Glycine iron sulphate (1:1)
EC 200-272-2
aminoacetate
Athenon
2-aminoacetate
Glycine (USP:INN)
NCGC00024503-01
Glycinum (INN-Latin)
Glicina (INN-Spanish)
GLYCINE (II)
GLYCINE [II]
GLYCINE (MART.)
GLYCINE [MART.]
Glycine, free base
GLYCINE (USP-RS)
GLYCINE [USP-RS]
GLYCINE (EP MONOGRAPH)
GLYCINE [EP MONOGRAPH]
GLYCINE (USP MONOGRAPH)
GLYCINE [USP MONOGRAPH]
Acide aminoacetique (INN-French)
Acido aminoacetico (INN-Spanish)
Acidum aminoaceticum (INN-Latin)
CAS-56-40-6
Glycine, labeled with carbon-14
AMINOACETIC ACID 1.5% IN PLASTIC CONTAINER
Aminoessigsaure
Aminoethanoate
18875-39-3
amino-Acetate
2-aminoaceticacid
[3H]glycine
Glycine USP grade
Glycine (Standard)
Glycine - EP
Glycine, EP/USP
H-Gly
L-Gly
Gly-CO
Gly-OH
L-Glycine,(S)
[14C]-glycine
Corilin (Salt/Mix)
Tocris-0219
Glycine (H-Gly-OH)
GLYCINE [VANDF]
NH2CH2COOH
GLYCINE [FHFI]
GLYCINE [HSDB]
Glycine, technical grade
GLYCINE [FCC]
GLYCINE [JAN]
GLYCINE [MI]
Glycine (JP18/USP)
Glycine, 99%, FCC
GLYCINE [WHO-DD]
Biomol-NT_000195
bmse000089
bmse000977
WLN: Z1VQ
Gly-253
GLYCINE [GREEN BOOK]
GTPL727
AB-131/40217813
GLYCINE [ORANGE BOOK]
Treating Gingivitis Toothpaste
Glycine, Electrophoresis Grade
BPBio1_001222
GTPL4084
GTPL4635
Repair Cracked Teeth Toothpaste
GLYCINE-1-13C-15N
BDBM18133
HY-Y0966R
AZD4282
MSK1408
Glycine, >=99.0% (NT)
Glycine, 98.5-101.5%
Pharmakon1600-01300021
Glycine 1000 microg/mL in Water
2-Aminoacetic acid;Aminoacetic acid
BCP25965
CS-B1641
EAA89676
HY-Y0966
Glycine, ACS reagent, >=98.5%
Tox21_113575
Glycine, 99%, natural, FCC, FG
HB0299
NSC760120
s4821
STL194276
Glycine, purum, >=98.5% (NT)
Glycine, tested according to Ph.Eur.
AKOS000119626
Glycine, for electrophoresis, >=99%
Tox21_113575_1
1ST1408
CAREDO Treating Gingivitis Toothpastes
CCG-266010
DB00145
FG02717
FG71510
NSC-760120
Glycine - Absolute carbon isotope ratio
Glycine, BioUltra, >=99.0% (NT)
Glycine, BioXtra, >=99% (titration)
SERINE IMPURITY B [EP IMPURITY]
CAREDO Repair Cracked Teeth Toothpastes
Glycine, SAJ special grade, >=99.0%
NCGC00024503-02
NCGC00024503-03
BP-31024
FG175750
Glycine, Vetec(TM) reagent grade, 98%
CAREDO Treating Gingivitis Toothpastes100g
DB-029870
G0099
G0317
Glycine, ReagentPlus(R), >=99% (HPLC)
NS00001575
CAREDO Repair Cracked Teeth Toothpastes100g
EN300-19731
C00037
C22407
D00011
D70890
M03001
L001246
Q620730
SR-01000597729
C-Terminal [mycofactocin precursor peptide]-glycine
Glycine, certified reference material, TraceCERT(R)
SR-01000597729-1
BRD-K72369578-001-04-1
Q27115084
B72BA06C-60E9-4A83-A24A-A2D7F465BB65
F2191-0197
Glycine, European Pharmacopoeia (EP) Reference Standard
Z955123660
Glycine, BioUltra, for molecular biology, >=99.0% (NT)
Glycine, from non-animal source, suitable for cell culture
InChI=1/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5
Glycine, United States Pharmacopeia (USP) Reference Standard
Glycine, Pharmaceutical Secondary Standard; Certified Reference Material
Glycine, analytical standard, for nitrogen determination according to Kjeldahl method
200-272-2
Glycine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, >=98.5%
Glycine, meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)