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Glycine Hydrochloride

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Identification
Molecular formula
C2H6ClNO2
CAS number
6000-43-7
IUPAC name
2-aminoacetic acid;hydrochloride
State
State

At room temperature, glycine hydrochloride is in a solid state. It exists as a stable crystalline powder that is commonly used in buffer solutions in laboratories due to its stability and solubility in water.

Melting point (Celsius)
208.00
Melting point (Kelvin)
481.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
111.54g/mol
Molar mass
111.5420g/mol
Density
1.3987g/cm3
Appearence

Glycine hydrochloride appears as a white crystalline powder. It is highly soluble in water, forming clear solutions. The compound is odorless and hygroscopic, meaning it can absorb moisture from the air. Its crystalline nature gives it a shiny, salt-like appearance.

Comment on solubility

Solubility of 2-Aminoacetic Acid Hydrochloride

2-Aminoacetic acid hydrochloride, commonly known as glycine hydrochloride, exhibits an intriguing solubility profile that makes it quite versatile in various applications. This compound is notably highly soluble in water, which can be attributed to its ionic nature and the presence of the amine and carboxyl functional groups that facilitate interactions with water molecules.

Key points about its solubility include:

  • High Hydrophilicity: The zwitterionic form of glycine allows for strong hydration shell formation, enhancing its solubility.
  • Temperature Dependence: As with many solutes, solubility typically increases with temperature, making it easier to dissolve at higher temperatures.
  • pH Influence: The solubility can vary with changes in pH; in acidic conditions, the compound remains protonated, maintaining solubility.

In summary, 2-aminoacetic acid hydrochloride is characterized by its remarkable solubility in polar solvents, particularly water, which is invaluable for its effectiveness in biochemical and pharmaceutical applications. Its ability to dissolve readily in aqueous solutions underscores its significance in various fields:

  1. Biochemistry
  2. Nutritional supplements
  3. Pharmaceutical formulations

Overall, glycine hydrochloride not only demonstrates excellent solubility but also serves as an essential building block in numerous biochemical processes, making it a compound of great interest in chemical science.

Interesting facts

Interesting Facts About 2-Aminoacetic Acid Hydrochloride

2-Aminoacetic acid, commonly known as glycine, is a fascinating compound that plays a critical role in biochemistry and various industries. Below are some engaging facts about this simple yet essential amino acid:

  • Building Block of Proteins: Glycine is one of the 20 standard amino acids used by cells to synthesize proteins. It is classified as a non-essential amino acid, meaning that the body can synthesize it and does not necessarily need to be obtained from the diet.
  • Neurotransmitter: It acts as an inhibitory neurotransmitter in the central nervous system, helping to regulate nerve impulses and enhance overall brain function.
  • Role in Collagen Formation: Glycine is a vital component in collagen, the most abundant protein in the human body. It contributes to the structural integrity of connective tissues, skin, bones, and cartilage.
  • Flavor Enhancer: Known for its slightly sweet taste, glycine is often used as a flavor enhancer in the food industry, making it popular in various culinary applications.
  • Metabolic Pathways: Glycine plays a role in several metabolic pathways, including the production of hormones and enzymes. It is also involved in the synthesis of glutathione, a potent antioxidant that helps protect cells from oxidative stress.

Utilizing glycine in the form of its hydrochloride salt further enhances its solubility in water, making it suitable for pharmaceutical formulations and nutritional supplements. As a scientist, one can appreciate its multifaceted roles, which extend beyond a mere building block of proteins, influencing biochemical pathways and biological functions crucial for life.

In the words of renowned biochemist Richard J. Roberts: "Understanding amino acids is fundamental to unraveling the complexities of life itself."

Glycine's simple structure belies its importance, accentuating its role as a fundamental compound in both chemistry and biology.

Synonyms
Glycine hydrochloride
6000-43-7
GLYCINE, HYDROCHLORIDE
GLYCINE HCl
Aminoacetic acid hydrochloride
Glycocoll hydrochloride
CCRIS 3355
EINECS 227-841-8
UNII-225ZLC74HX
225ZLC74HX
DTXSID7064079
GLYCINE HYDROCHLORIDE [II]
GLYCINE HYDROCHLORIDE [MI]
GLYCINE HYDROCHLORIDE [WHO-DD]
GLYCINE HYDROCHLORIDE (II)
Hydrochloride, Glycine
GLYCINE HCL [INCI]
DTXCID0042741
227-841-8
2-aminoacetic acid hydrochloride
glycine-hcl
MFCD00012872
Glycinehydrochloride
Glycin HCl
H-Gly-OH.HCl
SCHEMBL37746
Amino acetic acid hydrochloride
Glycine, hydrochloride (1:1)
AKOS015847938
FG40444
Glycine hydrochloride, >=99% (HPLC)
AS-15481
CS-0158475
G0103
NS00082374
EN300-31218
F21278
Q27253616
F1905-7104