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2-Aminoacetonitrile

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Identification
Molecular formula
C2H4N2
CAS number
540-61-4
IUPAC name
2-aminoacetonitrile
State
State

At room temperature, 2-aminoacetonitrile is typically found as a liquid.

Melting point (Celsius)
36.50
Melting point (Kelvin)
309.65
Boiling point (Celsius)
197.00
Boiling point (Kelvin)
470.15
General information
Molecular weight
56.06g/mol
Molar mass
56.0630g/mol
Density
1.0530g/cm3
Appearence

2-Aminoacetonitrile is a colorless to yellow liquid with a faint amine-like odor. It is hygroscopic and can absorb moisture from the air.

Comment on solubility

Solubility of 2-aminoacetonitrile

2-aminoacetonitrile, with the chemical formula C2H6N2, exhibits interesting solubility properties that make it a versatile molecule in various applications. Its solubility can be summarized as follows:

  • Polar Solvent Solubility: 2-aminoacetonitrile is soluble in water due to its ability to engage in hydrogen bonding. The presence of both the amino group (–NH2) and the nitrile group (–C≡N) enhances its interactions with water molecules.
  • Solubility in Organic Solvents: The compound is also soluble in various polar organic solvents, such as methanol and ethanol, making it useful for synthesis and analytical purposes.
  • Insolubility in Non-polar Solvents: It is typically insoluble in non-polar solvents, highlighting its polar nature and limiting its use in less polar environments.

In conclusion, the solubility of 2-aminoacetonitrile is primarily influenced by its polar functional groups, which allow for dissolution in various polar solvents but restrict its solubility in non-polar substances. As noted, “the chemistry of a compound often reflects its ability to engage with its environment,” and 2-aminoacetonitrile is no exception.

Interesting facts

Interesting Facts about 2-Aminoacetonitrile

2-Aminoacetonitrile is an organic compound that garners attention due to its unique structure and various applications in chemistry. Here are some compelling insights for any budding scientist or chemistry enthusiast:

  • Building Block for Pharmaceuticals: This compound serves as an essential precursor in the synthesis of a variety of pharmaceuticals. Its ability to provide an amino group and a nitrile functional group makes it a versatile building block.
  • Involvement in Peptide Synthesis: 2-Aminoacetonitrile is also utilized in peptide synthesis, where it can help create complex molecules needed in biological research.
  • Chemical Reactivity: The nitrile group in 2-aminoacetonitrile allows for nucleophilic reactions that are integral in forming more complex organic structures. This characteristic showcases its importance in organic synthesis.
  • Environmental Considerations: While working with this compound, it is crucial to acknowledge the environmental implications and potential toxicity of some nitrogen-containing compounds, highlighting the need for careful handling.
  • Research and Innovation: Scientists are continuously exploring new applications of 2-aminoacetonitrile, particularly in the fields of material science and biochemistry, emphasizing its relevance in contemporary research.

In the words of a renowned chemist, “The true beauty of chemistry lies in the transformations and the synthesis of something entirely new from simple, structured building blocks.” 2-Aminoacetonitrile embodies this philosophy, offering bright prospects for future discovery and application.


Whether you are studying organic synthesis, medicinal chemistry, or molecular design, understanding compounds like 2-aminoacetonitrile will undoubtedly enrich your educational journey.

Synonyms
Aminoacetonitrile
2-Aminoacetonitrile
540-61-4
Glycinonitrile
ACETONITRILE, AMINO-
Glycinenitrile
Cyanomethylamine
H2NCH2CN
EINECS 208-751-8
UNII-3739OQ10IJ
BRN 0773694
3739OQ10IJ
NCCH2NH2
.alpha.-Aminoacetonitrile
AMINOACETONITRILE [MI]
DTXSID90202314
2aminoacetonitrile
Acetonitrile, amino
alpha-Aminoacetonitrile
DTXCID90124805
208-751-8
4-04-00-02363 (beilstein handbook reference)
dfnygalunnfwkj-uhfffaoysa-n
ami-noacetonitrile
amino acetonitrile
amino-acetonitrile
methane, aminocyano-
Aminoacetonitrile, >=98%
CHEMBL1193997
540-61-4HCl
BBL009721
STL141086
AKOS000201450
DB-017501
CS-0498388
NS00032935
EN300-40750
G86136
Q48819
F1905-7133