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2-Aminobutanol

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Identification
Molecular formula
C4H11NO
CAS number
96-20-8
IUPAC name
2-aminobutan-1-ol
State
State
Liquid at room temperature, with a faint amine odor.
Melting point (Celsius)
-15.20
Melting point (Kelvin)
257.95
Boiling point (Celsius)
172.60
Boiling point (Kelvin)
445.75
General information
Molecular weight
89.14g/mol
Molar mass
89.1420g/mol
Density
0.9177g/cm3
Appearence

2-Aminobutanol is a colorless to slightly yellow liquid. It is hygroscopic, meaning it can absorb moisture from the air. The compound has a faint but characteristic amine-like odor.

Comment on solubility

Solubility of 2-aminobutan-1-ol

2-aminobutan-1-ol, a compound with the formula C4H11NO, exhibits notable solubility characteristics primarily due to its functional groups. Below are key points regarding its solubility:

  • Apolar vs. Polar: The presence of both an amine (-NH2) and a hydroxyl (-OH) group contributes to its polar nature, enhancing its solubility in polar solvents such as water.
  • Water Solubility: 2-aminobutan-1-ol is highly soluble in water. This is attributed to hydrogen bonding capabilities, which facilitate interactions with water molecules.
  • Solvent Interaction: It is also soluble in various organic solvents such as alcohols and acetone, where its polar character helps in dissolving within these environments.

In summary, the solubility of 2-aminobutan-1-ol can be summarized by saying:

"Its polarity, due to functional groups, strongly favors solubility in water and other polar solvents."

This makes 2-aminobutan-1-ol an interesting compound in terms of its ability to interact with different solvents, showcasing the influence of molecular structure on solubility.

Interesting facts

Interesting Facts about 2-Aminobutan-1-ol

2-Aminobutan-1-ol is an intriguing compound that falls within the category of amino alcohols. As a versatile intermediate, this compound plays a significant role in various chemical reactions and applications. Here are some notable aspects to consider:

  • Structure and Isomerism: 2-Aminobutan-1-ol features a four-carbon chain with both amino (–NH2) and hydroxyl (–OH) functional groups. This gives rise to a unique structural characteristic that allows it to participate in diverse chemical transformations.
  • Synthesis: This compound can be synthesized through multiple methods, including the reduction of amino acids or via reductive amination. The adaptability in its synthesis makes it an attractive target for chemists seeking functional group modifications.
  • Applications in Pharmaceuticals: Due to its amino and alcohol functionalities, 2-Aminobutan-1-ol is often explored for potential pharmaceutical applications. It can serve as a building block for the synthesis of biologically active compounds.
  • Role in Organic Chemistry: As a chiral precursor, 2-Aminobutan-1-ol is significant in the field of asymmetric synthesis, which is key to developing compounds with specific stereochemical configurations.
  • Research Opportunities: The study of 2-Aminobutan-1-ol presents numerous research opportunities in chemical reactivity, catalysis, and material science, making it a compound of interest in modern chemistry.

In summary, 2-Aminobutan-1-ol is not only a fascinating molecule in its own right but also a vital component in various chemical processes and research endeavors. Its dual functional groups provide a platform for innovative synthetic approaches and applications across multiple scientific fields.

As the acclaimed chemist Dale L. Boger once noted, "Chemistry is a science of change," and compounds like 2-Aminobutan-1-ol exemplify this dynamic nature of chemical science.

Synonyms
2-Aminobutan-1-ol
2-Amino-1-butanol
96-20-8
DL-2-Amino-1-butanol
2-Aminobutanol
1-BUTANOL, 2-AMINO-
1-Hydroxy-2-butylamine
aminobutanol
1-Hydroxybutan-2-amine
2-Amino-n-butyl alcohol
DL-2-Aminobutanol
NSC 1068
EINECS 202-488-2
EINECS 235-940-2
UNII-N008Q02GPS
BRN 1098274
N008Q02GPS
AI3-03357
1-Butanol, 2-amino-, (S)-
NSC-1068
AMINOBUTANOL [USP-RS]
DL-.ALPHA.-AMINOBUTANOL
DTXSID60859935
EC 202-488-2
2-AMINO-1-BUTANOL [MI]
4-04-00-01705 (Beilstein Handbook Reference)
AMINOBUTANOL (USP-RS)
ETHAMBUTOL HYDROCHLORIDE IMPURITY A [EP IMPURITY]
DL-alpha-Aminobutanol
ETHAMBUTOL HYDROCHLORIDE IMPURITY A (EP IMPURITY)
2Aminobutanol
Butanol2amine
2Aminobutan1ol
1Butanol, 2amino
1Hydroxy2butylamine
2Aminobutyl alcohol
2Amino1hydroxybutane
2Aminonbutyl alcohol
1(Hydroxymethyl)propylamine
2-AMINOBUTANOL [INCI]
DTXCID50209465
2-AMINO-1-BUTANOL, (+-)-
jcbpetkzigvzre-uhfffaoysa-n
un2735
13054-87-0
2-Aminobutyl alcohol
Butanol-2-amine
1-(Hydroxymethyl)propylamine
2-Amino-1-hydroxybutane
MFCD00008095
r-(-)-2-amino-1-butanol
(+/-)-2-Amino-1-butanol
2-Amino-butan-1-ol
( inverted exclamation markA)-2-Amino-1-butanol
MFCD00064419
butane, 2-amino-1-hydroxy-
L-2-AMINO-1-BUTANOL
H-Ala-Oet HCl
(-)-2-Aminobutanol
2-Amino-1-butanol #
R(-)-2-Amino-1-butanol
1-Hydroxy-2-aminobutane
1-Hydroxy-sec-butylamine
(rs)-2-amino-1-butanol
2-Amino-n-butanol
dl-2-amino-1butanol
rac-2-amino-1-butanol
(?)-2-Amino-1-butanol
Oprea1_102773
2-Amino-1-butanol, 97%
r-(-)-2 amino-1-butanol
WLN: ZY2&1Q
(+/-) 2-amino-1-butanol
.+/-.-2-Amino-1-butanol
CHEMBL327032
NSC1068
BCP16938
STR02718
1-(r,s)-(hydroxymethyl)propylamine
BBL027677
STL264181
AKOS000119782
AKOS016050696
SB44650
SB44694
SB83767
[(1R)-1-(hydroxymethyl)propyl]ammonium
1-Butanol, 2-amino-, (.+/-.)-
2-AMINO-1-BUTANOL, (+/-)-
SY049464
DB-016690
DB-016762
DB-031995
A0684
A8286
A8287
NS00001268
EN300-19709
D87517
Q27284318
F2190-0370
Z104474862
Aminobutanol, United States Pharmacopeia (USP) Reference Standard
Aminobutanol, Pharmaceutical Secondary Standard; Certified Reference Material