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Phenibut

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Identification
Molecular formula
C10H13NO2
CAS number
1078-21-3
IUPAC name
2-aminoethanol;2-phenylbutanoic acid
State
State
This compound is generally in a solid state at room temperature. It is often a crystalline powder and can be stored and handled as such.
Melting point (Celsius)
194.00
Melting point (Kelvin)
467.15
Boiling point (Celsius)
195.00
Boiling point (Kelvin)
468.15
General information
Molecular weight
179.22g/mol
Molar mass
179.2180g/mol
Density
1.1430g/cm3
Appearence

The compound appears as a white crystalline powder that is hygroscopic. It is often used in the racemic form, consisting of equal parts of two enantiomers. When dissolved, it is typically clear and colorless in solution.

Comment on solubility

Solubility of 2-Aminoethanol (C2H7NO)

2-Aminoethanol, often referred to as ethanolamine, exhibits a high degree of solubility in water. This property can be attributed to its ability to form hydrogen bonds due to the presence of both an amino group (-NH2) and a hydroxyl group (-OH) in its molecular structure. Key characteristics of the solubility of 2-aminoethanol include:

  • Highly soluble in water, making it useful in various applications such as a solvent and in pharmaceuticals.
  • Solubility decreases in nonpolar solvents, reflecting its polar nature.

As the solubility in water is a fundamental trait, it plays a crucial role in its functionality in biological and chemical processes.

Solubility of 2-Phenylbutanoic Acid (C10H12O2)

On the other hand, 2-phenylbutanoic acid demonstrates a more complex behavior regarding its solubility. As a carboxylic acid, it possesses some degree of polarity; however, the presence of the phenyl ring introduces significant hydrophobic character, affecting its solubility in various solvents. Consider the following points:

  • It is moderately soluble in organic solvents such as ethanol and ether.
  • Limited solubility in water, primarily due to the bulky phenyl group that hinders interaction with water molecules.
  • As temperature increases, solubility in water may improve slightly, showcasing typical behavior of organic acids.

Overall, understanding the solubility of 2-phenylbutanoic acid is vital for its application in organic synthesis and pharmaceuticals. Its unique properties highlight the balance between polar and nonpolar interactions in chemical behavior.

Interesting facts

Exploring 2-Aminoethanol

2-Aminoethanol, commonly known as ethanolamine, is an important compound in both industrial and academic settings. Here are some fascinating facts:

  • Versatile Applications: 2-Aminoethanol is utilized in producing a variety of chemicals, including detergents, emulsifiers, and pharmaceuticals.
  • Biological Significance: This compound is involved in the synthesis of phospholipids, which are crucial for cell membrane structure.
  • Amine Reaction: As a primary amine, it can undergo various chemical reactions including acylation, alkylation, and condensation.
  • Environmental Role: Ethanolamine also serves as a buffering agent used to neutralize acidic conditions in various applications.

Its dual functionality as both a base and a nucleophile makes 2-aminoethanol a unique compound worthy of study.


Diving into 2-Phenylbutanoic Acid

2-Phenylbutanoic acid is a compound that boasts intriguing features in organic synthesis and medicinal chemistry. Here’s what makes it stand out:

  • Key Intermediate: This compound is often used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals.
  • Selectivity in Reactions: It exhibits unique steric and electronic properties that make it a useful reagent in organic transformations.
  • Chiral Compound: 2-Phenylbutanoic acid possesses chiral centers, allowing for the production of stereochemically diverse compounds, which is essential in drug development.
  • Historical Relevance: Its derivatives have been studied extensively for their potential therapeutic effects and interactions with biological targets.

With its important role in synthesis and potential medicinal applications, 2-phenylbutanoic acid remains a vibrant subject of study for chemists.

Synonyms
Cetamiphen
Tstamifen
Cetimiphen
Phenexol
1870-65-1
2-phenylbutyrate-ethanolamine salt
DTXSID50940164
2-aminoethanol;2-phenylbutanoic acid
2-Phenylbutanoic acid--2-aminoethan-1-ol (1/1)