Skip to main content

Toluenesulfonic acid

ADVERTISEMENT
Identification
Molecular formula
C7H7NO6S
CAS number
104-15-4
IUPAC name
2-aminoethyl nitrate;4-methylbenzenesulfonic acid
State
State

At room temperature, 4-methylbenzenesulfonic acid is typically found as a solid. However, being highly hygroscopic, it may sometimes appear as a slightly moist solid due to the absorption of moisture from the air.

Melting point (Celsius)
103.00
Melting point (Kelvin)
376.15
Boiling point (Celsius)
140.20
Boiling point (Kelvin)
413.35
General information
Molecular weight
172.20g/mol
Molar mass
172.2040g/mol
Density
1.2450g/cm3
Appearence

4-Methylbenzenesulfonic acid, also known as toluenesulfonic acid (TsOH), typically appears as a white crystalline solid. It is very hygroscopic, meaning it can absorb moisture from the air, and sometimes it appears slightly damp due to this property. It is often found in its monohydrate form because of its ability to absorb water.

Comment on solubility

Solubility of 2-aminoethyl nitrate and 4-methylbenzenesulfonic acid

The solubility characteristics of 2-aminoethyl nitrate and 4-methylbenzenesulfonic acid are intriguing and vary significantly due to their distinct structural properties.

2-aminoethyl nitrate

2-aminoethyl nitrate, with its polar amine and nitrate functional groups, typically exhibits a high degree of solubility in water. Here are key points regarding its solubility:

  • Polar Nature: The presence of the amine group enhances interaction with water molecules.
  • Hydrophilicity: The nitrate moiety contributes to its solubility in polar solvents.
  • Temperature Dependence: Solubility may increase with temperature, common for ammonium nitrates.

4-methylbenzenesulfonic acid

This compound is also known for its solubility in water, accompanied by some interesting solvation characteristics:

  • Acidic Behavior: As a sulfonic acid, it readily donates protons, enhancing its solubility in aqueous solutions.
  • Electrostatic Interactions: The sulfonate group aids in solvation, creating favorable conditions for dissolving in water.
  • Polarity: The aromatic ring structure combined with the sulfonic acid function contributes to its ability to interact with a wide range of solvents.

In summary, both 2-aminoethyl nitrate and 4-methylbenzenesulfonic acid exhibit notable solubility in water, primarily due to their polar functional groups and the intrinsic nature of their respective structures. Understanding these solubility dynamics is essential in applications involving these compounds.

Interesting facts

Interesting Facts about 2-Aminoethyl Nitrate and 4-Methylbenzenesulfonic Acid

2-Aminoethyl Nitrate

2-Aminoethyl nitrate is an interesting compound that combines an amine group with a nitrate, showcasing an important area of study within organic chemistry. Here are some fascinating points about this compound:

  • Biological Relevance: This compound serves as a precursor in the synthesis of various pharmacologically active substances, illustrating its significance in medicinal chemistry.
  • Functional Versatility: The presence of both amino and nitrate functional groups provides opportunities for diverse chemical reactivity, making it a useful intermediate in organic synthesis.
  • Potential Uses: Research suggests it may have applications in fields ranging from agrochemicals to explosives, depending on the conditions of its usage.
  • Research Avenues: Scientists are continuously exploring this compound for its properties and potential applications, particularly in developing new materials.

4-Methylbenzenesulfonic Acid

4-Methylbenzenesulfonic acid, often referred to as p-toluenesulfonic acid, is a powerful acid and a versatile reagent frequently employed in organic synthesis. Here are some engaging aspects of this compound:

  • Proton Donor: As an acid, it acts as an excellent proton donor, enhancing its role as a catalyst in numerous chemical reactions.
  • Wide Application: It is widely utilized in the synthesis of esters, ethers, and many other organic compounds, highlighting its importance in both laboratory and industrial settings.
  • Hydrophilic Tail: The sulfonic acid group is highly polar, which helps in solubilizing organic compounds in polar solvents, making it a valuable addition in reactions that require increased solubility.
  • Research and Development: Ongoing studies are focused on its efficacy in promoting reactions under mild conditions, paving the way for greener chemistry practices.

Both 2-aminoethyl nitrate and 4-methylbenzenesulfonic acid exemplify the breadth and depth of organic chemistry, emphasizing the interconnectedness of compounds and their applications in various scientific fields.

Synonyms
Itramin tosylate
Cardisan
Nilatil
Tostram
Tostramin
Itramin tosilate
Tosilate d'itramine
13445-63-1
Tosilato de itramina
Itramini tosilas
Itramina tosilato
2-Aminoethylnitrate-p-toluenesulfonate
2-aminoethanol nitrate mono-p-toluenesulfonate
W9H0R50KY0
2-nitratoethylaminotoluene-p-sulfonate
CHEBI:136001
DTXSID30158705
2-aminoethanol nitrate mono(4-methylbenzenesulfonate)
2-Aminoethanol nitrate mono(4-methylbenzenesulfonate) ester
DTXCID9081196
C01DX01
Itramin tosilate [INN]
2-aminoethyl nitrate;4-methylbenzenesulfonic acid
2-Aminoethanol nitrate (ester) p-toluenesulfonate
Itramin tosilate (INN)
Itramini tosylas
Itramina tosilato [DCIT]
Ethanol, 2-amino-, nitrate, p-toluenesulfonate
Itramini tosilas [INN-Latin]
Tosilate d'itramine [INN-French]
Tosilato de itramina [INN-Spanish]
UNII-W9H0R50KY0
Ethanol, 2-amino-, nitrate (ester), mono-p-toluenesulfonate
Ethanol, 2-amino-, nitrate (ester), mono(4-methylbenzenesulfonate) (salt)
ITRAMIN TOSYLATE [MI]
SCHEMBL309020
CHEMBL2106780
ITRAMIN TOSILATE [WHO-DD]
2-aminoethyl nitrate 4-methylbenzenesulfonate
2-NITRATOETHYLAMINOTOLUENE-P-SULPHONATE
D07157
Q6094884
2-AMINOETHANOL NITRATE MONO-P-TOLUENESULPHONATE
4-methylbenzene-1-sulfonic acid--2-aminoethyl nitrate
2-AMINOETHANOL NITRATE (ESTER) P-TOLUENESULPHONATE
2-AMINOETHANOL NITRATE MONO(4-METHYLBENZENESULPHONATE)