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Doxorubicin

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Identification
Molecular formula
C27H29NO11
CAS number
23214-92-8
IUPAC name
2-[amino(hydroxy)methylene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione
State
State

At room temperature, Doxorubicin is a crystalline solid. However, for clinical use, it is often formulated as a liquid for intravenous injection as part of chemotherapy treatments.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
543.53g/mol
Molar mass
543.5260g/mol
Density
1.6000g/cm3
Appearence

Doxorubicin is typically a red-orange crystalline solid at room temperature. It has a characteristic appearance that is associated with its use as a chemotherapy drug. The coloration is due to its chromophore structure and is quite distinctive.

Comment on solubility

Solubility of 2-[amino(hydroxy)methylene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione

The compound with the formula C27H29NO11 exhibits a complex solubility profile that can be attributed to its unique chemical structure, which includes multiple functional groups. Here are some key points regarding its solubility:

  • Polar vs. Non-polar Solvent: Due to the presence of amino and hydroxy groups, this compound is likely soluble in polar solvents like water and alcohol.
  • Hydrogen Bonding: The numerous hydroxyl groups facilitate extensive hydrogen bonding, enhancing solubility in polar environments.
  • Dimethylamino Influence: The presence of a dimethylamino group may impart some degree of basicity, which can further affect solubility in aqueous media, particularly in acidic conditions.
  • Solubility in Organic Solvents: While it’s expected to be soluble in polar solvents, its solubility in non-polar organic solvents may be limited, indicating a preference for more polar environments.

In summary, the solubility of this compound can be predominantly characterized as polar soluble, with a tendency to dissolve well in solvents that facilitate hydrogen bonding. However, specific experimental data would provide a clearer understanding of its solubility behavior under various conditions.

Interesting facts

Interesting Facts About 2-[amino(hydroxy)methylene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione

This compound represents an intriguing blend of organic chemistry and potential applications in various fields. Its complex structure features multiple functional groups, which can impart unique chemical properties and biological activities. Here are some fascinating aspects of this compound:

  • Versatile Functional Groups: The presence of amino, hydroxy, and methyl groups indicates that this compound could participate in a variety of chemical reactions, making it a prime subject for synthetic organic chemistry.
  • Potential Biological Activity: Given its structure, it is worth investigating the compound's potential biological effects. Compounds like this are often studied for their pharmaceutical properties, including anti-inflammatory or anti-cancer activities.
  • Research Applications: This compound may serve as a valuable tool in research settings, especially in studies involving dye chemistry or as intermediates in the synthesis of more complex organic molecules.
  • Color Chemistry: Tetracene derivatives, such as this one, are known for their vibrant colors and photophysical properties, like fluorescence, making them useful in optoelectronic applications.

As stated by chemists in the field, "Understanding complex compounds paves the way for groundbreaking discoveries." This underscores the importance of studying compounds like 2-[amino(hydroxy)methylene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione, as they may lead to innovative solutions in chemical research and industry.

Overall, while the compound might seem esoteric at first glance, it holds the promise of expanding our understanding of organic chemistry and influencing fields such as pharmacology and materials science.