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Doxorubicin

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Identification
Molecular formula
C27H29N1O11
CAS number
23214-92-8
IUPAC name
2-[amino(hydroxy)methylene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
State
State

At room temperature, Doxorubicin is a solid. It is commonly stored as a powder for medical applications, and solutions are prepared for intravenous administration.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
273.00
General information
Molecular weight
543.53g/mol
Molar mass
543.5250g/mol
Density
1.6000g/cm3
Appearence

Doxorubicin is typically found as an orange-red crystalline solid. In practice, it is often available in powdered form for medical use, specifically in chemotherapy, or as a solution when dissolved for administration.

Comment on solubility

Solubility of 2-[amino(hydroxy)methylene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione (C27H29N1O11)

When assessing the solubility of the compound C27H29N1O11, it is crucial to consider its complex molecular structure, which presents unique challenges and characteristics in solvation. Generally, the solubility of organic compounds like this one can be influenced by several key factors:

  • Polarity: The presence of numerous hydroxyl (-OH) groups in the structure typically increases polarity, potentially enhancing solubility in polar solvents such as water.
  • Molecular Weight: With a relatively high molecular weight, solubility may be affected; larger molecules often have more restricted movement in solution.
  • Hydrogen Bonding: The functional groups capable of hydrogen bonding may facilitate solubility in protic solvents, leading to favorable interactions.
  • Conformational Flexibility: The tricyclic structure can introduce rigidity, which might hinder solubility compared to more flexible molecules.

In conclusion, while the compound C27H29N1O11 is likely to exhibit enhanced solubility in polar solvents due to its hydrogen bonding capabilities, challenges due to its size and potential rigidity should not be overlooked. Further experimental evaluation in various solvents would provide greater insights into its solubility behavior.

Interesting facts

Interesting Facts about 2-[amino(hydroxy)methylene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

This compound is a fascinating member of the tetracene family, well-known for its vibrant properties and potential applications in various fields. Here are some noteworthy points to consider:

  • Complex Structure: The structural complexity of this compound arises from its tetracyclic core, featuring a combination of hydroxyl and amino groups that contribute to its unique reactivity and stability.
  • Versatile Applications: Compounds like this one are often studied for their potential use in organic electronics, photovoltaics, and as fluorescent dyes due to their strong optical properties.
  • Stability Considerations: The presence of multiple hydroxy groups enhances the solubility and stabilization of the compound, making it a target for chemical modification in synthetic applications.
  • Research Significance: Tetracenes, especially substituted ones, are researched intensively for their properties as semiconductors and in the development of organic light-emitting diodes (OLEDs).
  • Interdisciplinary Interest: This compound bridges chemistry with materials science, physics, and even engineering, reflecting the multidisciplinary nature of modern scientific research.

As stated by a prominent researcher in organic materials:
"The journey into the electronic properties of these compounds unveils infinite possibilities for innovation in technology."

In conclusion, the multifaceted nature of this compound, with its distinctive chemical attributes and wide-ranging applications, makes it a prime subject for ongoing scientific exploration and innovation.