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Doxycycline

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Identification
Molecular formula
C22H24N2O8Cl
CAS number
564-25-0
IUPAC name
2-[amino(hydroxy)methylene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
State
State

Doxycycline is typically in a solid state at room temperature. It is generally supplied in the form of capsules or tablets for medical use. As a solid, it may be a powder or a crystalline form when isolated in its pure compound state.

Melting point (Celsius)
201.50
Melting point (Kelvin)
474.65
Boiling point (Celsius)
870.00
Boiling point (Kelvin)
1 143.15
General information
Molecular weight
444.44g/mol
Molar mass
444.4360g/mol
Density
1.5400g/cm3
Appearence

Doxycycline is typically found as fine, yellow, crystalline powder. It is known for its distinctive yellowish color and crystalline texture, characteristic of many tetracycline antibiotics.

Comment on solubility

Solubility of 2-[amino(hydroxy)methylene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

This compound, with the chemical formula C22H24N2O8Cl, exhibits fascinating solubility characteristics influenced by its complex structure and the presence of multiple functional groups. Here are some key points to consider:

  • Polarity: The presence of hydroxyl groups (-OH) tends to increase solubility in polar solvents, suggesting that this compound may be more soluble in water or alcohols.
  • Chlorine Atom: The chlorine atom introduces a degree of hydrophobic character, which could limit solubility in very polar solvents but may enhance solubility in organic solvents.
  • Dimethylamino Group: This functional group may also affect solubility, as it is typically more soluble in polar media due to its ability to form hydrogen bonds.
  • Overall Behavior: Given the combination of hydrophilic and hydrophobic features, it is likely that the compound has moderate solubility in water with better solubility in organic solvents.

In summary, the solubility of 2-[amino(hydroxy)methylene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione can be characterized as:

  • Moderately soluble in water due to functional groups capable of hydrogen bonding.
  • More soluble in organic solvents because of the hydrophobic parts of the molecule.

Understanding the solubility of this compound is crucial for applications in various fields, including pharmaceuticals and material sciences, where solvent interaction plays a pivotal role.

Interesting facts

Interesting Facts about 2-[amino(hydroxy)methylene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

This complex compound, a member of the tetracene family, is noteworthy for its fascinating structure and potential applications. Here are some interesting highlights:

  • Structure Diversity: The compound features a tetracene backbone, which is known for its linear polycyclic structure. This unique arrangement provides various reactive sites that could be crucial for chemical reactivity and biological interactions.
  • Chloro-substitution: The presence of chlorine, particularly at the 7-position, is significant as it can enhance the compound's lipophilicity, allowing better interaction with biological membranes, which could be advantageous in medicinal chemistry.
  • Dimethylamino Group: The dimethylamino group adds to the complexity of this molecule. It can engage in hydrogen bonding and enhance solubility, impacting the compound's overall pharmacological properties.
  • Potential Uses: This compound may exhibit properties that make it suitable for various applications including, but not limited to, pharmaceuticals, dyes, and sensors. Its structural features are similar to some important biomolecules, suggesting a role in biological processes or as a synthetic intermediate.

Moreover, compounds like this have been of great interest in fields such as organic electronics and photochemistry, where their electronic properties can lead to exciting advancements. As a result, continued research and exploration of such complex compounds can unveil new insights and innovations.

In the words of renowned chemist Linus Pauling, "Chemistry is the science of connection and transformation." This compound exemplifies this statement, showcasing how molecules can interconnectedly operate as agents of change in various scientific arenas.