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Neomycin sulfate

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Identification
Molecular formula
C23H46N6O13 · 2H2SO4
CAS number
1405-10-3
IUPAC name
2-(aminomethyl)-6-[4,6-diamino-3-[4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]tetrahydropyran-3,4,5-triol;sulfuric acid
State
State

At room temperature, it is in a solid state as a powder.

Melting point (Celsius)
260.00
Melting point (Kelvin)
533.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
614.63g/mol
Molar mass
614.6280g/mol
Density
1.4300g/cm3
Appearence

Neomycin sulfate appears as a white or slightly yellow, hygroscopic powder. It is water-soluble and can form a clear solution.

Comment on solubility

Solubility of 2-(aminomethyl)-6-[4,6-diamino-3-[4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]tetrahydropyran-3,4,5-triol in Sulfuric Acid

The compound 2-(aminomethyl)-6-[4,6-diamino-3-[4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]tetrahydropyran-3,4,5-triol, particularly when combined with sulfuric acid, showcases intriguing solubility characteristics. Given the complex nature of this molecule, its solubility can be influenced by several factors:

  • Polarity: The numerous hydroxyl (-OH) groups present typically enhance solubility in polar solvents, such as sulfuric acid, facilitating interactions that promote dissolution.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds with sulfuric acid may significantly improve its solubility, as these interactions help to stabilize the solute within the solvent environment.
  • Functional Groups: The presence of amino (-NH2) groups suggests that both the compound and sulfuric acid can engage in proton transfer, which further modifies the solubility dynamics.

In summary, this compound is expected to exhibit good solubility in sulfuric acid, primarily due to its polar nature and the potential for extensive interaction through hydrogen bonding. However, the actual solubility can be influenced by factors such as temperature, concentration, and the overall structural compatibility of the compound with the solvent.

Interesting facts

Interesting Facts About the Compound: 2-(Aminomethyl)-6-[4,6-diamino-3-[4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]tetrahydropyran-3,4,5-triol; sulfuric acid

This compound is a fascinating example of the intricate world of organic chemistry, showcasing a rich structure that combines multiple functional groups. Its complexity not only reflects intriguing chemical properties but also opens doors to a variety of biological applications. Here are some noteworthy points worth considering:

  • Multi-functional Nature: This compound contains both amino and hydroxyl groups, which can act as chemical sites for further modifications or interactions, greatly enhancing its versatility in various chemical environments.
  • Potential Biological Activity: Similar compounds are often studied for their roles in pharmaceuticals. The presence of multiple amine groups suggests potential activity as a drug candidate, especially in the field of antitumor and antibiotic research.
  • Complex Synthesis: The synthesis of this compound is likely to involve multiple steps, combining strategies such as functional group protection, selective deprotection, and coupling reactions. This complexity can make the synthesis rewarding yet challenging for chemists.
  • Hydrophilicity: Given the abundance of hydroxyl and amino groups, this compound is expected to exhibit strong hydrophilic characteristics, which can influence its solubility and interaction with biological systems.
  • Role of Sulfuric Acid: The presence of sulfuric acid indicates its use as a catalyst or a reactant, which can facilitate certain reactions or enhance yield in synthesis. It is a powerful dehydrating agent often utilized in organic reactions.
  • Insights into Stereochemistry: The configuration of multiple chiral centers in this compound could provide rich opportunities to explore stereochemistry, which plays a crucial role in determining the biological activity of drugs.

In summary, the study of this compound not only unveils the beauty of molecular architecture but also emphasizes the significance of organic compounds in medicine and industry. As researchers continue to explore its properties, we may discover even more profound implications for its application in the pharmaceutical domain and beyond.

Synonyms
70560-51-9
RefChem:792628
Kanamycin sulfate mixture OF components A,B and C
684-844-0
Kanamycin sulfate
Kanamycin sulfate (1:1) (salt)
Kanamycin sulphate
1966115-71-8
C18H38N4O15S
2-(aminomethyl)-6-[4,6-diamino-3-[4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid
KANAMYCIN MONO SULFATE
Prestwick_596
SCHEMBL17913127
DTXSID10911592
OOYGSFOGFJDDHP-UHFFFAOYSA-N
HMS1569O09
AKOS004910322
AC-20043
Kanamycin sulfate from Streptomyces kanamyceticus powder
2-(aminomethyl)-6-[4,6-diamino-3-[4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]tetrahydropyran-3,4,5-triol;sulfuric acid
4,6-diamino-3-[(6-amino-6-deoxyhexopyranosyl)oxy]-2-hydroxycyclohexyl 3-amino-3-deoxyhexopyranoside sulfate (1:1)