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2-Aminobenzyl alcohol

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Identification
Molecular formula
C7H9NO
CAS number
534-16-7
IUPAC name
(2-aminophenyl)methanol
State
State
At room temperature, 2-Aminobenzyl alcohol is typically found in the solid state. It may be used in crystal or powder form depending on the application.
Melting point (Celsius)
58.00
Melting point (Kelvin)
331.15
Boiling point (Celsius)
244.00
Boiling point (Kelvin)
517.15
General information
Molecular weight
123.15g/mol
Molar mass
123.1520g/mol
Density
1.0945g/cm3
Appearence
2-Aminobenzyl alcohol is a crystalline solid that appears as colorless to light yellow crystals or powder. It is slightly soluble in water and has a characteristic aromatic amine odor.
Comment on solubility

Solubility of (2-aminophenyl)methanol

(2-aminophenyl)methanol, with its unique molecular structure, exhibits intriguing solubility characteristics that are important for various applications. This compound primarily shows solubility in organic solvents due to its polar functional groups. Here are some key points to consider:

  • Polar vs. Non-Polar Solubility: Being a polar compound, (2-aminophenyl)methanol is expected to be soluble in polar solvents, such as water and alcohols, while exhibiting low solubility in non-polar solvents like hexane.
  • Hydrogen Bonding: The presence of the hydroxyl (-OH) and amino (-NH2) groups allows (2-aminophenyl)methanol to engage in hydrogen bonding, enhancing its solubility in polar environments.
  • Temperature Influence: Generally, solubility can increase with temperature; thus, heating the solvent may improve the dissolving capacity of (2-aminophenyl)methanol.

In summary, the solubility of (2-aminophenyl)methanol can be described as follows:

  1. Soluble in polar solvents (e.g., water, ethanol)
  2. Limited solubility in non-polar solvents (e.g., hexane)
  3. Increased solubility with higher temperatures

Understanding the solubility of this compound is crucial for its applications in pharmaceuticals, materials science, and organic synthesis.

Interesting facts

Interesting Facts About (2-aminophenyl)methanol

(2-aminophenyl)methanol, also known as o-aminobenzyl alcohol, is a fascinating compound with numerous applications and unique properties that intrigue chemists and researchers alike. Here's why this compound stands out:

  • Dual Functional Group: This compound features both a hydroxyl group (–OH) and an amine group (–NH2), allowing it to participate in a variety of chemical reactions, making it a versatile molecule in organic synthesis.
  • Synthesis Versatility: The compound can be synthesized through various methods, including reduction processes involving nitro compounds or via nucleophilic substitution reactions, providing ample opportunities for exploration in synthetic chemistry.
  • Pharmaceutical Potential: Certain derivatives of (2-aminophenyl)methanol have been investigated for their bioactivity and potential use in pharmaceuticals. Their unique structure may lead to compounds with promising therapeutic effects.
  • Understanding Structure-Activity Relationships: The presence of both amine and hydroxyl groups allows scientists to explore structure-activity relationships (SARs) which can lead to enhanced efficacy in drug discovery.
  • Applications in Material Science: Beyond pharmaceuticals, (2-aminophenyl)methanol can be utilized in the development of polymers and other materials, highlighting its usefulness beyond traditional chemical applications.

As researchers delve deeper into the properties and applications of (2-aminophenyl)methanol, they are continually uncovering new potentials for this intriguing compound. Its ability to bridge gaps between organic synthesis and applied chemistry makes it a valuable subject for study among students and professionals alike.

Synonyms
2-Aminobenzyl alcohol
5344-90-1
(2-Aminophenyl)methanol
2-aminobenzylalcohol
2-Aminobenzenemethanol
o-Aminobenzyl alcohol
Benzenemethanol, 2-amino-
o-(Hydroxymethyl)aniline
o-Aminobenzylic alcohol
2-Hydroxymethylaniline
BENZYL ALCOHOL, o-AMINO-
NSC 1173
JK3AH3NG9C
EINECS 226-293-7
o-Aminophenylcarbinol
BRN 1072211
(o-Aminophenyl)methanol
NSC-1173
UNII-JK3AH3NG9C
DTXSID6063800
EC 226-293-7
3-13-00-01615 (Beilstein Handbook Reference)
oAminobenzyl alcohol
2Aminobenzenemethanol
oAminobenzylic alcohol
Benzyl alcohol, oamino
o(Hydroxymethyl)aniline
Benzenemethanol, 2amino
DTXCID0041436
226-293-7
inchi=1/c7h9no/c8-7-4-2-1-3-6(7)5-9/h1-4,9h,5,8h
vyfoavadnihptr-uhfffaoysa-n
(2-Amino-phenyl)-methanol
MFCD00007749
O-AMINO-BENZYLALCOHOL
(2-aminophenyl)-methanol
2-(Hydroxymethyl)aniline
1bio
o-aminobenzylalcohol
Mianserin Hydrochloride Imp. C (EP); Mianserin Imp. C (EP); (2-Aminophenyl)methanol; Benzocaine Impurity B; Mianserin Hydrochloride Impurity C; Mianserin Impurity C
2-aminophenylmethanol
0-aminobenzyl alcohol
2-amino-benzylalcohol
o-amino-benzyl alcohol
2-amino-benzenemethanol
2-amino-benzyl alcohol
WLN: ZR B1Q
Oprea1_783408
SCHEMBL16252
2-Aminobenzyl alcohol, 98%
CHEMBL1235999
NSC1173
STR03329
BBL027657
STK077953
AKOS000119677
CS-W004705
DB03058
FA64445
HY-W004705
PB47249
PS-3377
AC-11377
SY006439
DB-020514
A1000
NS00004005
EN300-21387
A829598
AC-907/25014178
Q27094019
F0001-1388
Z104495736
2-Hydroxymethyl aniline; 2-Aminobenzyl alcohol; 2-Amino-benzenemethanol