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2-Amino-3-hydroxypyridine

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Identification
Molecular formula
C5H6N2O
CAS number
16867-03-1
IUPAC name
2-aminopyridin-3-ol
State
State

The compound is typically in a solid state at room temperature, appearing as a powder or crystalline solid.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
335.00
Boiling point (Kelvin)
608.15
General information
Molecular weight
110.12g/mol
Molar mass
110.1160g/mol
Density
1.3000g/cm3
Appearence

2-Amino-3-hydroxypyridine typically appears as a fluffy, off-white to yellow crystalline powder. It may also be available in a more granular form depending on the source and purification level.

Comment on solubility

Solubility of 2-Aminopyridin-3-ol

2-Aminopyridin-3-ol, with the chemical formula C5H6N2O, exhibits interesting solubility characteristics that can be impacted by various factors. Understanding these properties is crucial for applications in pharmaceuticals and organic synthesis.

General Solubility

This compound is generally considered to be:

  • Soluble in water: 2-Aminopyridin-3-ol can readily dissolve in water due to its polar amino and hydroxyl groups, leading to the formation of hydrogen bonds with water molecules.
  • Soluble in organic solvents: It also demonstrates solubility in several organic solvents, which can include ethanol and dimethyl sulfoxide (DMSO), making it versatile for various chemical reactions.

Factors Influencing Solubility

Several factors can influence the solubility of 2-aminopyridin-3-ol:

  • pH of the solution: The ionization state of the amino and hydroxyl groups will affect solubility; in acidic conditions, it may become protonated, enhancing its solubility.
  • Temperature: Increased temperature generally improves solubility for many compounds, including this one.
  • Concentration of solutes: The presence of various solutes can alter the solubility dynamics through competition for solvent molecules.

In conclusion, the solubility of 2-aminopyridin-3-ol is influenced by its structural properties and external conditions. As one explores its applications, considering these solubility traits will be key to effectively utilizing this compound in different scenarios.

Interesting facts

Interesting Facts about 2-Aminopyridin-3-ol

2-Aminopyridin-3-ol is a fascinating compound with diverse applications, reflecting its significance in various scientific fields. Here are some engaging insights:

Key Characteristics

  • Structural Affinity: This compound belongs to the class of aminopyridines, which are known for their potential in medicinal chemistry and material science.
  • Functional Versatility: The presence of both an amino group and a hydroxyl group allows for interesting reactivity and the ability to form hydrogen bonds, making it a valuable intermediate in organic synthesis.
  • Biological Importance: Compounds related to 2-aminopyridin-3-ol have been studied for their role in the development of pharmaceuticals, particularly in drugs targeting central nervous system disorders.

Applications and Uses

2-Aminopyridin-3-ol finds utility in several important areas:

  • Pharmaceuticals: As a building block for synthesizing bioactive molecules, it plays a vital role in drug discovery.
  • Agriculture: Research indicates potential use in agrochemicals due to its ability to interact with specific enzymes.
  • Material Science: It may serve as a precursor for novel materials with unique properties.

Chemical Behavior

The compound demonstrates intriguing chemical behavior, such as:

  • Protonation: The amino group can be protonated under acidic conditions, expanding its reactivity.
  • Reactivity: With electrophiles, its nucleophilic site on the amino group makes it a target for substitution reactions.

Overall, 2-aminopyridin-3-ol exemplifies the intricate connection between structure and function, showcasing why scientists and researchers are drawn to its study.

Synonyms
2-AMINO-3-HYDROXYPYRIDINE
16867-03-1
2-Amino-3-pyridinol
3-Pyridinol, 2-amino-
3-Hydroxy-2-pyridinamine
3-HYDROXY-2-AMINOPYRIDINE
3-Pyridinol, 2-amino
P8740PEW4B
JAROCOL 2A3HP
RODOL 2A3PYR
NSC-136806
DTXSID50168588
DTXCID4091079
240-886-8
2-Aminopyridin-3-ol
2-amino-pyridin-3-ol
MFCD00006317
2-Amino-3-pyridol
2-amino-3-hydroxy-pyridine
2-AMINO-3-HYDROXY PYRIDINE
UNII-P8740PEW4B
EINECS 240-886-8
NSC136806
NSC 136806
AI3-61061
2-amino-3hydroxypyridine
2-amino-3 -hydroxypyridine
SCHEMBL33700
orb1299381
SCHEMBL3077950
SCHEMBL5644255
CHEMBL4777856
SCHEMBL29358060
BMTSZVZQNMNPCT-UHFFFAOYSA-
CHEBI:195501
2-Amino-3-hydroxypyridine, 98%
KUC106690N
BCP22160
STR03035
BBL009590
MSK000276
SBB028186
STK730134
AKOS000119509
AB00700
AC-2461
CS-W007794
HY-W007794
PS-3161
PD211469
KSC-11-207-21
DB-015933
A1089
NS00001163
ST51040590
EN300-21313
P16526
Q27286357
F2158-1509
Z104495292
2-Amino-3-hydroxypyridine, Vetec(TM) reagent grade, 98%
2-Amino-3-pyridinol;3-hydroxy-2-aminopyridine;2-Amino-3-pyridinol
InChI=1/C5H6N2O/c6-5-4(8)2-1-3-7-5/h1-3,8H,(H2,6,7)