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2-Aminothiazol-4-one

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Identification
Molecular formula
C3H4N2OS
CAS number
96-54-8
IUPAC name
2-aminothiazol-4-one
State
State

At room temperature, 2-Aminothiazol-4-one is in a solid state. Its crystalline nature contributes to its stability and ease of handling under various laboratory conditions.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
263.00
Boiling point (Kelvin)
536.15
General information
Molecular weight
114.13g/mol
Molar mass
114.1340g/mol
Density
1.4970g/cm3
Appearence

2-Aminothiazol-4-one typically appears as an off-white or pale yellow crystalline powder. It may agglomerate into larger crystals over time. The compound's appearance can vary somewhat depending on its purity and specific form.

Comment on solubility

Solubility of 2-aminothiazol-4-one

The solubility of 2-aminothiazol-4-one can be an intriguing aspect of its chemical properties. Understanding the solubility of this compound is essential for various applications, ranging from pharmaceutical formulations to industrial processes. Here are some key points regarding its solubility:

  • Solvent Compatibility: 2-aminothiazol-4-one generally exhibits solubility in polar solvents such as water and alcohols. This characteristic is mainly due to its ability to form hydrogen bonds.
  • Temperature Dependence: Like many organic compounds, the solubility of 2-aminothiazol-4-one may increase with temperature. Higher temperatures can enhance the interaction between the solute and solvent molecules.
  • pH Influence: The solubility can also be affected by the pH of the solution. In an acidic environment, the protonation of the amino group may influence solubility positively.
  • Formulation Considerations: In practical applications, when formulating solutions that contain 2-aminothiazol-4-one, it’s crucial to consider factors such as ionic strength and the presence of co-solvents, which can significantly alter its solubility profile.

In summary, the solubility of 2-aminothiazol-4-one is influenced by various factors including solvent type, temperature, and pH. Understanding these elements can aid in optimizing the compound’s use in many chemical and biological contexts.

Interesting facts

Interesting Facts about 2-Aminothiazol-4-one

2-Aminothiazol-4-one is a fascinating organic compound with a variety of applications in the field of chemistry and pharmacology. This compound belongs to the thiazole family, which is characterized by a sulfur and nitrogen containing ring structure that imparts unique properties.

Key Characteristics:

  • Antimicrobial Activity: One of the most notable features of 2-aminothiazol-4-one is its potential as an antimicrobial agent. Researchers have investigated its efficacy against various bacterial strains, making it a candidate for further drug development.
  • Amino Group Influence: The presence of the amino group in the 2-position enhances the compound's reactivity, allowing for the potential modification of its structure and the design of new derivatives with improved biological activities.
  • Thiazole Ring System: The thiazole ring not only contributes to the biological activity but also plays a vital role in electronic properties, making this compound interesting for applications in materials science.
  • Drug Development: Compounds such as 2-aminothiazol-4-one serve as a crucial starting point for the synthesis of a wide range of pharmaceuticals, particularly in the search for novel therapeutic agents.

Chemical Biology Aspects:

Studies indicate that the mechanism of action for 2-aminothiazol-4-one may involve inhibition of specific enzymes within pathogens, showcasing the importance of understanding molecular interactions in drug design. As one scientist noted, "The thiazole moiety often serves as a pharmacophore, enabling targeted action in biological systems."

Overall, 2-aminothiazol-4-one exemplifies the intersection of organic chemistry, medicinal chemistry, and biological research, making it a compound of great interest to scientists and researchers alike. Its role in drug discovery and potential therapeutic applications ensures that it will remain a subject of study in various scientific fields for years to come.

Synonyms
4(5H)-Thiazolone, 2-amino-
USAF DM-1
2-Amino-2-thiazolin-4-one
2-Imino-4-thiazolidone
USAF BE-4-5
4-THIAZOLIDINONE, 2-IMINO-
2-Thiazolin-4-one, 2-amino-
4,5-Imidazolidinedithione
NSC 2858
NSC 45956
DTXSID9060312
DTXCID6041923
2-Thiazolin-4-one, 2-amino-(8CI)
209-145-6
2-imino-1,3-thiazol-4-one
ai3-17191
einecs 209-145-6
2-Imino-4-thiazolidinone
2-Imino-1,3-thiazolidin-4-one
2-amino-1,3-thiazol-4-one
2-imino-thiazolidin-4-one
pseudo-Thiohydantoin
2-amino-thiazol-4-one
2-iminothiazolidin-4-one
2-AMINO-4,5-DIHYDRO-1,3-THIAZOL-4-ONE
2-amino-1,3-thiazol-4(5H)-one
4(5H)-Thiazolone, 2-imino-
NSC2858
NSC-2858
NSC45956
NSC-45956
HYMJHROUVPWYNQ-UHFFFAOYSA-
WLN: T5MYYM EHJ BUS CUS
2-AMINO-1,3-THIAZOLIN-4-ONE
Pseudohydantoin
4-thiazolol, 2-amino-
Pseudothiohydantoin, 97%
4, 5-Imidazolidinedithione
EFJ392NV7F
MLS006011410
SCHEMBL160875
2-Thiazolin-4-one, 2-imino-
2-Imino-1,3-thiazolidin-4-one #
GEO-02173
STK078756
STK159520
AKOS000119449
AKOS002245219
PS-4535
SMR004703239
SY034788
NS00043042
EN300-17927
AB00443393-03
AE-641/00665038
SR-01000945159
SR-01000945159-1
Z57104428
F3284-3349