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2-(Aziridin-1-yl)-1-phenylethanol

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Identification
Molecular formula
C10H13NO
CAS number
1003-21-4
IUPAC name
2-(aziridin-1-yl)-1-phenyl-ethanol
State
State

At room temperature, 2-(Aziridin-1-yl)-1-phenylethanol is typically in a liquid state.

Melting point (Celsius)
13.00
Melting point (Kelvin)
286.15
Boiling point (Celsius)
123.00
Boiling point (Kelvin)
396.15
General information
Molecular weight
163.22g/mol
Molar mass
163.2150g/mol
Density
1.0869g/cm3
Appearence

2-(Aziridin-1-yl)-1-phenylethanol typically appears as a colorless to pale yellow liquid. It may have a faint aromatic odor associated with the phenyl group present in the compound.

Comment on solubility

Solubility of 2-(aziridin-1-yl)-1-phenyl-ethanol

The solubility of the compound 2-(aziridin-1-yl)-1-phenyl-ethanol can be influenced by various factors due to its unique structure. Here are some key points to consider:

  • Polarity: The presence of both an aziridine ring and a phenyl group suggests a balance between polar and nonpolar characteristics. This may enhance its solubility in polar solvents such as water and alcohols, while also allowing for some degree of solubility in nonpolar solvents.
  • Hydrogen Bonding: The hydroxyl (-OH) group present in the structure contributes to its ability to form hydrogen bonds, which can further increase solubility in polar solvents.
  • Temperature Dependence: The solubility may vary with temperature; generally, increased temperature tends to enhance the solubility of organic compounds.
  • pH Influence: Being an alcohol, the solubility could also be affected by pH levels, especially in aqueous solutions where ionization may occur at extremes of pH.

In summary, while 2-(aziridin-1-yl)-1-phenyl-ethanol may exhibit moderate solubility in polar solvents due to hydrogen bonding, its overall solubility characteristics will depend on the specific conditions, such as temperature and solvent choice. Understanding these factors is crucial for practical applications in synthesis and formulation.

Interesting facts

Interesting Facts about 2-(aziridin-1-yl)-1-phenyl-ethanol

2-(aziridin-1-yl)-1-phenyl-ethanol is a fascinating compound with unique structural characteristics and potential applications in various scientific fields. Here are some intriguing aspects of this compound:

  • Aziridine Ring Structure: The presence of the aziridine ring, a three-membered nitrogen-containing heterocycle, contributes to the compound’s reactivity and versatility. Aziridines are known for their ability to participate in various chemical reactions, making them essential building blocks in organic synthesis.
  • Pharmaceutical Potential: Compounds containing aziridine moieties have shown promise in medicinal chemistry. They are often investigated for their potential as antitumor, antiviral, and antibacterial agents due to their unique reactivity profiles.
  • Chiral Center: The alcohol functional group in this compound creates a chiral center, which may lead to interesting stereochemical properties. Chirality is a vital aspect of drug design, as the different enantiomers of a compound can exhibit significantly different biological activities.
  • Versatile Intermediate: As an intermediate in organic synthesis, 2-(aziridin-1-yl)-1-phenyl-ethanol can be used to synthesize a variety of other compounds, showcasing its importance in the development of more complex molecules.
  • Research Applications: Ongoing research focuses on elucidating the mechanisms by which aziridine-containing compounds interact with biological systems. Understanding these mechanisms can lead to the design of more effective therapeutic agents.

In summary, 2-(aziridin-1-yl)-1-phenyl-ethanol is not just a chemical compound; it represents a bridge between fundamental research and practical applications in fields such as medicinal chemistry and organic synthesis. With its distinctive features, it offers a rich area for exploration and discovery within the realm of chemistry.

Synonyms
17918-11-5
alpha-Phenyl-1-aziridineethanol
1-AZIRIDINEETHANOL, alpha-PHENYL-
1-Aziridineethanol, .alpha.-phenyl-
Ethanol, 2-(1-aziridinyl)-1-phenyl-
EINECS 241-861-4
NSC 152375
BRN 0132133
alpha-(1-Aziridinylmethyl)benzyl alcohol
AI3-50475
Benzyl alcohol, alpha-(1-aziridinylmethyl)-
Benzenemethanol, alpha-(1-aziridinylmethyl)-
DTXSID50884998
5-20-01-00021 (Beilstein Handbook Reference)
DTXCID601024411
1-Aziridineethanol, alpha-phenyl-, (+-)-
1-Aziridineethanol, .alpha.-phenyl-, (.+-.)-
15591-40-9
605-034-5
alpha-Phenylaziridine-1-ethanol
2-(aziridin-1-yl)-1-phenylethanol
.alpha.-(1-Aziridinylmethyl)benzyl alcohol
WLN: T3NTJ A1YQR
SCHEMBL10746494
.alpha.-Phenyl-1-aziridineethanol
NSC152375
1-(2-hydroxy-2-phenylethyl)aziridine
NSC-152375
1-(2'-hydroxy-2'-phenylethyl)aziridine
1-hydroxy-1-phenyl-2-ethyleniminoethane
NS00052961
Benzenemethanol, .alpha.-(1-aziridinylmethyl)-
Benzyl alcohol, .alpha.-(1-aziridinylmethyl)-