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HFP Oxaziridine

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Identification
Molecular formula
C5H5F6NO
CAS number
344-44-5
IUPAC name
2-(aziridin-1-yl)-1,1,1,3,3,3-hexafluoro-propan-2-ol
State
State

The compound is typically in a liquid state at room temperature but can solidify near its melting point around 17°C. It is generally handled as a liquid in various applications and experimental protocols.

Melting point (Celsius)
17.00
Melting point (Kelvin)
290.15
Boiling point (Celsius)
98.00
Boiling point (Kelvin)
371.15
General information
Molecular weight
209.09g/mol
Molar mass
209.0780g/mol
Density
1.4750g/cm3
Appearence

The compound is usually a colorless liquid. It may not have a strong odor and is primarily used or studied in laboratory settings.

Comment on solubility

Solubility Insights for 2-(aziridin-1-yl)-1,1,1,3,3,3-hexafluoro-propan-2-ol

The solubility of 2-(aziridin-1-yl)-1,1,1,3,3,3-hexafluoro-propan-2-ol is an intriguing subject due to its unique molecular structure and the influence of fluorine atoms. Understanding its solubility can be approached through several factors:

  • Polarity: The presence of multiple fluorine atoms contributes to a high degree of molecular polarity, enhancing solubility in polar solvents.
  • Hydrogen Bonding: The hydroxyl (-OH) group in this compound can participate in hydrogen bonding, which plays a crucial role in its interactions with polar solvents such as water.
  • Amine Interactions: The aziridine structure adds a basic amine component that may influence solubility by forming additional interactions in certain solvent environments.
  • Fluorinated Characteristics: Due to the predominance of fluorine, this compound may exhibit unique solubility properties that differ from non-fluorinated counterparts, potentially making it more soluble in specialized organic solvents.

In summary, the solubility of 2-(aziridin-1-yl)-1,1,1,3,3,3-hexafluoro-propan-2-ol may be generally described as relatively high in polar solvents but requires careful consideration of the solvent environment due to the interplay of several factors. As expressed in the words of chemists, "The solubility behavior of such compounds often defies conventional expectations, presenting delightful surprises in practical applications." The assessment of solubility for this compound can, therefore, lead to intriguing insights in both academic and industrial contexts.

Interesting facts

Interesting Facts about 2-(aziridin-1-yl)-1,1,1,3,3,3-hexafluoro-propan-2-ol

2-(aziridin-1-yl)-1,1,1,3,3,3-hexafluoro-propan-2-ol, often referred to as a fluorinated alcohol, is a fascinating compound that presents unique characteristics and potential applications in various fields. Here are some interesting aspects:

  • Fluorination Effect: The presence of six fluorine atoms significantly alters the chemical properties of the compound, influencing its reactivity and stability. Fluorinated compounds often exhibit enhanced lipophilicity, making them suitable for a variety of biochemical applications.
  • Aziridine Ring: The compound features an aziridine moiety, a three-membered cyclic amine known for its high reactivity. This small ring structure can open up numerous synthetic pathways and lead to the formation of various derivatives.
  • Potential in Pharmaceuticals: Given its unique structure, this compound may provide advantages in drug design, especially in creating novel therapeutic agents with desirable pharmacokinetic properties due to its fluorinated nature.
  • Green Chemistry: Compounds like 2-(aziridin-1-yl)-1,1,1,3,3,3-hexafluoro-propan-2-ol play a vital role in green chemistry initiatives, as they can be utilized in reactions requiring high selectivity and minimal waste production.
  • Research Focus: Ongoing research is being conducted to explore the full capabilities of this compound, particularly in material science and catalysis, where its distinctive properties could lead to innovative solutions.

In summary, 2-(aziridin-1-yl)-1,1,1,3,3,3-hexafluoro-propan-2-ol is not just an interesting chemical compound; it is a window into the broader implications of fluorination and ring structures in chemical synthesis and application. As the field of chemistry continues to evolve, compounds like this one will undoubtedly contribute to new scientific discoveries.

Synonyms
773-23-9
1-AZIRIDINEMETHANOL, alpha,alpha-BIS(TRIFLUOROMETHYL)-
alpha,alpha-Bis(trifluoromethyl)-1-aziridinemethanol
J6R8WF8SLK
NSC-101314
.alpha.,.alpha.-Bis(trifluoromethyl)-1-aziridinemethanol
NSC 101314
BRN 1308354
WLN: T3NTJ AXQXFFFXFFF
NSC101314
UNII-J6R8WF8SLK
5-20-01-00027 (Beilstein Handbook Reference)
1-Aziridinemethanol, .alpha.,.alpha.-bis(trifluoromethyl)-
DTXSID30228018
1-Aziridinemethanol,.alpha.-bis(trifluoromethyl)-