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2-(Aziridin-1-yl)ethanol

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Identification
Molecular formula
C4H9NO
CAS number
36403-69-9
IUPAC name
2-(aziridin-1-yl)ethanol
State
State

At room temperature, 2-(Aziridin-1-yl)ethanol exists as a liquid. It is miscible with water and many organic solvents, making it suitable for various chemical reactions and applications.

Melting point (Celsius)
49.00
Melting point (Kelvin)
322.15
Boiling point (Celsius)
217.00
Boiling point (Kelvin)
490.15
General information
Molecular weight
87.12g/mol
Molar mass
87.1170g/mol
Density
1.0830g/cm3
Appearence

2-(Aziridin-1-yl)ethanol is typically a colorless to pale yellow liquid. It has a noticeable amine-like odor and may appear clear or slightly viscous depending on its purity and concentration.

Comment on solubility

Solubility of 2-(aziridin-1-yl)ethanol

2-(aziridin-1-yl)ethanol is an intriguing compound that exhibits moderate solubility in a variety of solvents. The solubility characteristics of this compound are influenced by its unique molecular structure, which includes a 5-membered aziridine ring and a hydroxyl group. Here are some key points regarding its solubility:

  • Polar Solvents: 2-(aziridin-1-yl)ethanol shows a tendency to dissolve well in polar solvents such as water and alcohols. The presence of the hydroxyl group (-OH) in its structure facilitates hydrogen bonding, enhancing its solubility in these media.
  • Non-Polar Solvents: In non-polar solvents, the solubility is significantly lower. This is attributed to the hydrophilic nature of the hydroxyl group, which is not compatible with non-polar environments.
  • Temperature Effects: The solubility can vary with temperature, typically increasing as the temperature rises, which enhances molecular interactions and overall solubility.
  • Derivative Formation: The formation of derivatives or complexes can also affect solubility. For instance, substituting functional groups may modify solubility characteristics, making it essential to evaluate each variant individually.

In summary, the solubility of 2-(aziridin-1-yl)ethanol is primarily dictated by its hydrophilic properties and can be classified as moderate to high in polar solvents, demonstrating the importance of functional groups in determining solubility behavior.

Interesting facts

Interesting Facts about 2-(Aziridin-1-yl)ethanol

2-(Aziridin-1-yl)ethanol is a fascinating compound that belongs to the category of aziridine derivatives. This compound offers intriguing properties and applications that pique the interest of both chemists and researchers. Here are some key highlights:

  • Structure and Stability: The aziridine ring is a three-membered nitrogen-containing heterocycle, known for its unique reactivity and potential stability under certain conditions. This makes it a subject of interest in synthetic chemistry.
  • Biological Relevance: Compounds like 2-(aziridin-1-yl)ethanol are notable for their biological activity. They are often investigated for their potential as pharmaceutical intermediates or as building blocks for drug synthesis, particularly in the field of medicinal chemistry.
  • Reactivity: The presence of both an aziridine moiety and an alcohol functional group allows for versatile reactivity patterns. This dual functionality can lead to interesting reactions, such as ring-opening reactions or the formation of esters.
  • Applications: Beyond its theoretical significance, 2-(aziridin-1-yl)ethanol may find applications in materials science or the development of novel polymers. The incorporation of aziridine units can enhance the mechanical properties of polymeric materials.
  • Research Potential: Ongoing studies are exploring the potential of this compound in fields ranging from organic synthesis to drug development. As researchers delve deeper, we may discover new pathways and reactions that increase its utility.

In summary, 2-(aziridin-1-yl)ethanol stands at the crossroads of organic synthesis and biological research, making it an exciting compound to study. Its unique structure and reactivity not only contribute to its scientific relevance but also open doors for innovative applications across various disciplines.

Synonyms
1-AZIRIDINEETHANOL
1072-52-2
2-(aziridin-1-yl)ethanol
2-(1-Aziridinyl)ethanol
1-Azirdineethanol
1-(2-Hydroxyethyl)ethylenimine
N-(2-Hydroxyethyl)aziridine
2-(Azidin-1-yl)ethanol
N-(2-Hydroxyethyl)ethylenimine
N-(Hydroxyethyl)ethyleneimine
Ethanol, 2-(1-aziridinyl)-
N-(2-Hydroxyethyl)ethyleneimine
Hydroxyethylethyleneimine
1-(2-Hydroxylethyl)aziridine
2-Hydroxy-1-ethylaziridine
N-Hydroxyethyl ethylene imine
beta-Hydroxy-1-ethylaziridine
NSC 50209
N-(beta-Hydroxyethyl)aziridine
CCRIS 5164
HSDB 2860
N-(.beta.-Hydroxyethyl)aziridine
EINECS 214-009-4
BRN 0102514
R20BLL91L5
AI3-50768
NSC-50209
DTXSID0024551
1-AZIRIDINEETHANOL [HSDB]
5-20-01-00014 (Beilstein Handbook Reference)
2-(1-AZIRIDINYL)ETHANOL [IARC]
2-(1-AZIRIDINYL)ETHANOL (IARC)
1Azirdineethanol
1-aziridine ethanol
2(1Aziridinyl)ethanol
2Hydroxy1ethylaziridine
betaHydroxy1ethylaziridine
N(2Hydroxyethyl)aziridine
Ethanol, 2(1aziridinyl)
N(betaHydroxyethyl)aziridine
N(Hydroxyethyl)ethyleneimine
NHydroxyethyl ethylene imine
N(2Hydroxyethyl)ethylenimine
1(2Hydroxyethyl)ethylenimine
N(2Hydroxyethyl)ethyleneimine
n-(2-hydroxyethyl)-aziridine
DTXCID304551
n-(2-hydroxyethyl) ethyleneimine
2-(1-AZIRIDINYL) ETHANOL
3-HYDROXY-1-ETHYL AZIRIDINE
N-(BETA-HYDROXYETHYL)AZIRIDENE
1-(2-HYDROXYETHYL) ETHYLENIMINE
Aziridineethanol
1-(2-Hydroxyethyl)ethyleneimine
2-(aziridin-1-yl)ethan-1-ol
2-aziridin-1-ylethanol
1-Aziridineethanol (>90%)
(2-Hydroxy-1-ethyl)aziridine
CHEBI:82393
(.beta.-Hydroxy-1-ethyl)aziridine
UNII-R20BLL91L5
2-aziridinylethanol
1-aziridine-ethanol
MFCD00005119
2-Aziridin-1-yl-ethanol
WLN: T3NTJ A2Q
2-(aziridine-1-yl)ethanol
N-(ss-Hydroxyethyl)aziridine
CHEMBL118671
VYONOYYDEFODAJ-UHFFFAOYSA-
NSC50209
AKOS000119435
CS-W023058
FA06930
GS-3669
DB-226192
H0567
NS00021489
EN300-20517
C19332
Q27155916
InChI=1/C4H9NO/c6-4-3-5-1-2-5/h6H,1-4H2