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Fluoxetine

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Identification
Molecular formula
C17H18F3NO
CAS number
54910-89-3
IUPAC name
2-benzamido-3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid
State
State

At room temperature, fluoxetine is in a solid state, appearing as small crystals or powder.

Melting point (Celsius)
179.00
Melting point (Kelvin)
452.15
Boiling point (Celsius)
287.90
Boiling point (Kelvin)
561.05
General information
Molecular weight
309.33g/mol
Molar mass
309.3320g/mol
Density
1.2820g/cm3
Appearence

Fluoxetine is typically found as a white to off-white crystalline solid. It is not hygroscopic and has a characteristic odor.

Comment on solubility

Solubility of 2-benzamido-3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid

The solubility of a compound like 2-benzamido-3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid is influenced by various factors, including its chemical structure, polarity, and the nature of its substituents. Here are some considerations regarding its solubility:

  • Polarity: The presence of the amino groups and the fluorinated ethyl residues contributes to its overall polarity. Increased polarity generally enhances solubility in polar solvents.
  • Hydrogen Bonding: This compound can engage in hydrogen bonding due to the amide linkage, which can significantly affect its solubility, particularly in polar solvents like water.
  • Hydrophobic Interactions: The aromatic rings and aliphatic fluorinated segments may lead to hydrophobic interactions, potentially reducing solubility in highly polar solvents while enhancing it in non-polar solvents.
  • pH Dependency: The functional groups present may lead to ionization at various pH levels, affecting solubility. For acidic compounds like this, solubility often increases in alkaline conditions.

Overall, one might say, "The solubility of a compound is as important as its structure," because understanding these interactions helps predict its behavior in different environments. Therefore, determining the solubility requires careful consideration of all these factors, making it crucial for applications in pharmaceutical and material sciences.

Interesting facts

Interesting Facts about 2-benzamido-3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid

2-benzamido-3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid, often referred to in shorthand as a complex amide compound, has several noteworthy characteristics that make it a subject of interest in the field of medicinal chemistry.

Key Highlights:

  • Unique Structure: This compound features a distinctive structure that includes both an amide linkage and a propanoic acid moiety, which can influence its biological activity.
  • Fluoroethyl Substituents: The presence of bis(2-fluoroethyl) groups is intriguing, as fluorine atoms can enhance the compound's metabolic stability and lipophilicity, often leading to improved pharmacokinetic properties.
  • Potential Applications: Compounds with similar structures have been investigated for use in anti-cancer therapies and as modulators in various biological pathways, signifying a potential role in drug development.

Moreover, compounds like this one can undergo various biochemical transformations, which could lead to the discovery of new therapeutic agents. As researchers dive deeper into the interactions and modifications of compounds with these types of functional groups, we might unlock further potential applications that could significantly impact health sciences.

In summary, exploring the intricacies of 2-benzamido-3-[4-[bis(2-fluoroethyl)amino]phenyl]propanoic acid not only showcases the beauty of chemical diversity but also highlights the complex interplay between chemical structure and biological activity, making it an exciting topic for ongoing research.

Synonyms
N-Benzoyl-3-(p-(bis(2-fluoroethyl)amino)phenyl)alanine
4092-83-5
NSC 82216
NSC82216
ALANINE, N-BENZOYL-3-(p-(BIS(2-FLUOROETHYL)AMINO)PHENYL)-
NCIOpen2_009125
NSC-82216