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N-(Phenylsulfonyl)glycine

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Identification
Molecular formula
C9H9NO4S
CAS number
968-22-7
IUPAC name
2-[benzenesulfonyl(methyl)amino]acetic acid
State
State

At room temperature, N-(Phenylsulfonyl)glycine is in a solid state, specifically as a white crystalline powder.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
276.00
Boiling point (Kelvin)
549.15
General information
Molecular weight
213.23g/mol
Molar mass
213.2290g/mol
Density
1.3980g/cm3
Appearence

N-(Phenylsulfonyl)glycine appears as a white crystalline solid. It is typically available as a powder that is odorless.

Comment on solubility

Solubility of 2-[benzenesulfonyl(methyl)amino]acetic acid (C9H9NO4S)

The solubility of 2-[benzenesulfonyl(methyl)amino]acetic acid in various solvents can be quite intriguing due to its unique chemical structure. Here are some key points regarding its solubility:

  • Polar Solvents: This compound tends to be more soluble in polar solvents such as water and alcohols. The presence of the carboxylic acid group contributes significantly to this solubility.
  • Non-Polar Solvents: Conversely, it exhibits limited solubility in non-polar solvents, such as hexane or toluene, because of its polar functional groups.
  • pH Influence: The solubility can also be affected by pH levels, with higher solubility often observed in acidic conditions due to the protonation of the amino group.
  • Temperature Dependence: As with many organic acids, an increase in temperature may enhance solubility, allowing more of the compound to dissolve in a solvent.

In summary, **2-[benzenesulfonyl(methyl)amino]acetic acid** showcases interesting solubility characteristics influenced by its molecular structure and environmental conditions. Understanding these factors can be crucial for applications in medicinal chemistry and pharmaceutical formulations.

Interesting facts

Interesting Facts about 2-[benzenesulfonyl(methyl)amino]acetic acid

2-[benzenesulfonyl(methyl)amino]acetic acid is a fascinating compound that bridges the fields of organic chemistry and medicinal applications. Here’s why it deserves attention:

  • Versatile Application: This compound has been studied for its potential use in pharmaceuticals, especially as an anti-inflammatory agent. The presence of the sulfonyl and amino groups enhances its biological activity.
  • Functional Groups: The structure harbors unique functional groups that facilitate interactions in biological systems, making it a point of interest for drug development.
  • Synthesis: Its synthesis often involves sophisticated synthetic routes, showcasing the intricacies of organic reactions and the importance of protecting groups in organic synthesis.
  • Research Relevance: Ongoing research focuses on how modifying this compound’s structure could enhance its efficacy or reduce side effects, aligning with the principles of structure-activity relationships (SAR) in medicinal chemistry.

The study of 2-[benzenesulfonyl(methyl)amino]acetic acid represents a compelling convergence of chemistry and medicine. The possibilities for innovation in drug discovery speak to the heart of why many chemists are passionate about their work. As stated by Marie Curie, “Nothing in life is to be feared, it is only to be understood." Research in compounds like this invites a deeper understanding of the molecular intricacies that drive biological systems.


In conclusion, examining this compound not only enriches one’s knowledge of organic chemistry but also provides a glimpse into the potential future advancements in therapeutic agents!

Synonyms
46376-16-3
N-Phenylsulfonyl-Sarcosine
N-METHYL-N-(PHENYLSULFONYL)GLYCINE
PHENYLSULFONYL-SAR-OH
2-[benzenesulfonyl(methyl)amino]acetic acid
n-(phenylsulfonyl)sarcosine
Glycine, N-methyl-N-(phenylsulfonyl)-
2-(N-methylbenzenesulfonamido)acetic acid
2-(N-Methylphenylsulfonamido)acetic acid
PHENYLSULFONYL-N-ME-GLY-OH
DTXSID50196821
2-(benzenesulfonyl(methyl)amino)acetic acid
Phenylsulfonyl-Aar-OH
[methyl(phenylsulfonyl)amino]acetic acid
N-Phenylsulfonyl-N-methylglycine
MFCD00031398
N-Benzenesulfonyl-sarcosine
N-(phenylsulfonyl)-sarcosine
AO-080/40711745
SCHEMBL2334379
DTXCID90119312
XQGWHYCLQRSQSQ-UHFFFAOYSA-N
ALBB-023718
Glycine,N-methyl-N-(phenylsulfonyl)-
AKOS000132767
SB79910
AS-58856
(benzenesulfonyl-methyl-amino)-acetic acid
DB-051373
CS-0210274
NS00008263
(N-METHYLBENZENESULFONAMIDO)ACETIC ACID
EN300-36249
A12541
Z45715513
839-943-5