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Tolfenamic acid

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Identification
Molecular formula
C14H11NO2
CAS number
13710-19-5
IUPAC name
2-benzhydryloxy-N'-hydroxy-acetamidine
State
State

At room temperature, Tolfenamic acid is in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
211.00
Melting point (Kelvin)
484.15
Boiling point (Celsius)
387.00
Boiling point (Kelvin)
660.15
General information
Molecular weight
261.31g/mol
Molar mass
261.3050g/mol
Density
1.2120g/cm3
Appearence

Tolfenamic acid typically appears as a white to off-white crystalline powder. The powder is slightly soluble in water, giving it a somewhat coarse texture, and is more soluble in organic solvents.

Comment on solubility

Solubility of 2-benzhydryloxy-N'-hydroxy-acetamidine

The solubility of 2-benzhydryloxy-N'-hydroxy-acetamidine can be attributed to several factors, including its chemical structure and the presence of functional groups. Here are some important aspects to consider:

  • Hydrophilicity vs Hydrophobicity: The compound features both hydrophobic (aromatic rings) and hydrophilic (hydroxyl and amine groups) characteristics. This dual nature can affect its solubility in different solvents.
  • Solvent Compatibility: 2-benzhydryloxy-N'-hydroxy-acetamidine is likely to be more soluble in polar solvents like water or alcohols due to hydrogen bonding capabilities provided by the hydroxyl groups.
  • Temperature Influence: As with many compounds, an increase in temperature may enhance its solubility. Heat typically increases the kinetic energy of molecules, which can help overcome intermolecular forces.

Overall, while we can predict certain solubility behaviors based on structural analysis and the functional groups present, experimental determination remains essential for precise solubility data. Keep in mind that solubility can vary significantly based on environmental conditions such as pH and temperature.

Interesting facts

Interesting Facts about 2-benzhydryloxy-N'-hydroxy-acetamidine

2-benzhydryloxy-N'-hydroxy-acetamidine is a fascinating chemical compound known for its unique structure and potential applications in medicinal chemistry. Here are some key points about this intriguing compound:

  • Dual Functionality: The presence of both an amidine and a hydroxyl group in its structure allows this compound to exhibit versatile reactivity and potentially interact with various biological targets.
  • Source of Interest: Researchers are particularly interested in 2-benzhydryloxy-N'-hydroxy-acetamidine due to its implications in the development of new therapeutic agents. It can serve as a lead compound in the synthesis of molecules that may treat various diseases.
  • Mechanistic Insights: The compound's structure suggests that it could play a role in enzyme inhibition or act as an effective ligand, which is of paramount importance for drugs interacting with specific biological macromolecules.
  • Potential in Drug Design: With ongoing research in the pharmaceutical industry, compounds like 2-benzhydryloxy-N'-hydroxy-acetamidine are vital for exploratory studies, leading to the discovery of innovative drug candidates.
  • Real-world Applications: The distinctive features of this compound could lead to potential applications in areas such as cancer therapy, neurology, or infectious diseases, underscoring the importance of this research in drug development.

As a student or scientist delving into the world of organic compounds, understanding the properties and potential applications of 2-benzhydryloxy-N'-hydroxy-acetamidine can provide significant insights into the complexities of chemical reactivity and medicinal chemistry.

In the words of famous chemist Marie Curie, "Nothing in life is to be feared, it is only to be understood." This compound embodies the spirit of exploration and understanding in the quest for new therapeutic interventions.

Synonyms
SCHEMBL1520589