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Clomiphene citrate

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Identification
Molecular formula
C32H36ClNO8
CAS number
50-41-9
IUPAC name
2-benzhydryloxy-N'-hydroxy-acetamidine;but-2-enedioic acid
State
State

At room temperature, clomiphene citrate is present as a solid.

Melting point (Celsius)
116.00
Melting point (Kelvin)
389.15
Boiling point (Celsius)
510.00
Boiling point (Kelvin)
783.15
General information
Molecular weight
598.09g/mol
Molar mass
598.0920g/mol
Density
1.2800g/cm3
Appearence

Clomiphene citrate usually appears as a white to pale yellow powder. It is practically odorless and soluble in water.

Comment on solubility

Solubility of 2-benzhydryloxy-N'-hydroxy-acetamidine; but-2-enedioic acid

The solubility of the compound 2-benzhydryloxy-N'-hydroxy-acetamidine; but-2-enedioic acid can pose a fascinating subject of study. Being a complex molecular structure, solubility can vary significantly depending on various factors, including polarity, temperature, and the solvent used. Here are some key points to consider:

  • Polarity: This compound features both polar and non-polar groups. The presence of the hydroxyl (-OH) group generally increases solubility in polar solvents, such as water, while the hydrophobic benzhydryl moiety may hinder it.
  • Temperature: Increasing temperature usually enhances solubility for solid compounds. Therefore, warming a saturated solution might dissolve more of the substance.
  • Solvent Choice: Solubility is highly dependent on the solvent. For instance, while it may be poorly soluble in non-polar solvents like hexane, it may have better solubility in polar organic solvents such as methanol or ethanol.

As a rule of thumb, the solubility can be described in terms of like dissolves like: similar characteristics in solvents and solutes can lead to better solubility. Thus, exploring different conditions and solvents will greatly contribute to understanding the solubility profile of this compound.

Interesting facts

Interesting Facts about 2-benzhydryloxy-N'-hydroxy-acetamidine;but-2-enedioic acid

This fascinating compound boasts a unique combination of functional groups that contribute to its intriguing properties and potential applications. Here are some captivating insights:

  • Dual Nature: The presence of both an acetamidine and a dicarboxylic acid structure allows for versatile interactions, making this compound noteworthy in chemical synthesis and medicinal chemistry.
  • Biological Relevance: Compounds of this type often serve as important intermediates in drug development, particularly in the design of inhibitors for various biological targets.
  • Mechanism Insights: Its hydroxyl groups may partake in hydrogen bonding, influencing both solubility and reactivity, which is crucial when considering its behavior in biological systems.
  • Potential Applications: Due to its structural characteristics, this compound could be explored for use in pharmaceuticals, agrochemicals, and as biochemical probes in research.
  • Research Interest: The study of such compounds may unlock new pathways in organic chemistry, aiding in the discovery of novel mechanisms or reactions.
  • Synthetic Versatility: The synthesis of compounds like this can often involve various approaches, including functional group modifications and coupling reactions, showcasing the creativity involved in organic synthesis.

As a scientist, exploring compounds like 2-benzhydryloxy-N'-hydroxy-acetamidine;but-2-enedioic acid opens a door to a world of possibilities, emphasizing the interconnectedness of chemical structures and their applications in real-world scenarios.