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Modafinil

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Identification
Molecular formula
C15H15NO2S
CAS number
68693-11-8
IUPAC name
2-benzhydrylsulfinylacetamide
State
State

At room temperature, modafinil is a solid.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.15
Boiling point (Celsius)
501.80
Boiling point (Kelvin)
774.95
General information
Molecular weight
273.35g/mol
Molar mass
273.3510g/mol
Density
1.1000g/cm3
Appearence

Modafinil appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-benzhydrylsulfinylacetamide

2-benzhydrylsulfinylacetamide (C15H15NO2S) presents interesting characteristics regarding its solubility. This compound, primarily composed of a sulfinyl group and acetamide, can exhibit solubility behavior that is influenced by several factors:

  • Polarity: The presence of the sulfinyl and amide groups contributes to the polarity of the molecule, enhancing its solubility in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The ability of the amide part to engage in hydrogen bonding can further facilitate solubility in polar media.
  • Solvent Type: 2-benzhydrylsulfinylacetamide is likely to be less soluble in non-polar solvents due to its polar functional groups.

It is important to note that solubility may also depend on factors such as temperature and pH, exhibiting different behaviors under various conditions. This adaptability makes the study of its solubility behavior particularly fascinating.

As a general observation, compounds in this category can often be soluble in the following:

  • Water — Depending on the concentration.
  • Ethanol — More favorable due to similar polar characteristics.
  • DMSO (Dimethyl sulfoxide) — As a polar aprotic solvent enhances solubility.

In conclusion, while the exact solubility can vary, understanding the impact of structural features and environmental conditions is crucial for predicting the behavior of 2-benzhydrylsulfinylacetamide in various solutions.

Interesting facts

Interesting Facts about 2-benzhydrylsulfinylacetamide

2-benzhydrylsulfinylacetamide is a fascinating compound that has garnered interest in various fields, particularly in medicinal chemistry. Here are some intriguing aspects about this compound:

  • Medicinal Potential: This compound is being studied for its potential therapeutic benefits, highlighting its role in drug development. The sulfinyl group can influence biological activity and efficacy, making it a compound of interest for researchers.
  • Structural Novelty: The presence of both a sulfinyl and an acetamide group introduces a level of structural diversity that can lead to interesting interactions within biological systems. This unique structure is essential in understanding how the compound interacts at the molecular level.
  • Pharmacophore Insights: As a part of a pharmacophore model, 2-benzhydrylsulfinylacetamide provides insights into how structural features correlate with biological effectiveness. The arrangement of functional groups can significantly affect receptor interactions, essential in drug design.
  • Research Applications: Scientists frequently employ this compound in research to explore its reactivity and stability, contributing to broader investigations about similar sulfinyl-containing compounds.
  • Interdisciplinary Studies: The study of 2-benzhydrylsulfinylacetamide often intersects with fields such as organic chemistry, pharmacology, and material science, showcasing its versatility as a research molecule.

Overall, 2-benzhydrylsulfinylacetamide's distinctive chemical properties and potential applications make it a compelling subject for ongoing scientific inquiry.

Synonyms
modafinil
68693-11-8
Provigil
Modiodal
2-[(diphenylmethyl)sulfinyl]acetamide
2-(Benzhydrylsulfinyl)acetamide
Modafinilum [Latin]
2-benzhydrylsulfinylacetamide
modaphonil
Modafinilo
Modafinilo [Spanish]
CRL 40476
(+-)-Modafinil
Modafinilum
Alertec
Modafinil civ
R Modafinil
CEP 1538
CRL-40476
(+/-)-Modafinil
2-((Diphenylmethyl)sulfinyl)acetamide
Modavigil
UNII-R3UK8X3U3D
CEP-1538
R3UK8X3U3D
NSC-751178
NSC-759110
DTXSID0023329
Acetamide, 2-((diphenylmethyl)sulfinyl)-
HSDB 7585
THN102 COMPONENT MODAFINIL
DEP-1538
THN-102 COMPONENT MODAFINIL
CRC-40476
112111-49-6
CHEMBL1373
DTXCID103329
CHEBI:77585
Modafinil [USAN:USP:INN:BAN]
Modafinilum (Latin)
2-(Diphenyl-methanesulfinyl)-acetamide
NSC 751178
NSC 759110
NCGC00095176-03
Sparlon
MODAFINIL (MART.)
MODAFINIL [MART.]
Modafinil [USAN:INN]
MODAFINIL CIV (USP-RS)
MODAFINIL CIV [USP-RS]
MODAFINIL (EP MONOGRAPH)
MODAFINIL [EP MONOGRAPH]
MODAFINIL (USP MONOGRAPH)
MODAFINIL [USP MONOGRAPH]
Modafinil (USAN:USP:INN:BAN)
Moderateafinil
SMR000058957
CAS-68693-11-8
SR-01000759419
NH 02D
NH-02D
Attenace
Modalert
Modasomil
CRL 40983
CRL-40983
DEA No. 1680
Armodafinil D10
2-(diphenylmethyl)sulfinylacetamide
Provigil (TN)
MODAFINIL [INN]
MODAFINIL [JAN]
MODAFINIL [MI]
MODAFINIL [HSDB]
MODAFINIL [USAN]
Spectrum2_001712
MODAFINIL [VANDF]
MODAFINIL [WHO-DD]
Modafinil (JAN/USP/INN)
UNII-152JRG3T0U
SCHEMBL34488
BSPBio_002270
MLS000759427
MLS001424049
BIDD:GT0714
SPECTRUM1505361
(-)benzhydrylsulphinylacetamide
SPBio_001724
GTPL7555
MODAFINIL [ORANGE BOOK]
Modafinil, >=98% (HPLC)
CHEBI:31859
AFT-801
N06BA07
HMS1922F12
HMS2051P17
HMS2093D15
HMS3264I03
HMS3393P17
HMS3713C12
Pharmakon1600-01504283
Pharmakon1600-01505361
2-(diphenylmethane)sulfinylacetamide
2-(diphenylmethyl)sulfinylethanamide
BCP28422
Tox21_111470
BDBM50156055
CCG-39511
CN 801
CN-801
GRL 40476
HB0860
HY-15201A
MFCD00868082
NSC751178
NSC751850
NSC758711
NSC759110
2-[di(phenyl)methylsulfinyl]acetamide
Modafinil 1.0 mg/ml in Acetonitrile
AKOS004118314
Tox21_111470_1
2-[(diphenylmethyl)sulfinyl]-acetamide
AC-1382
DB00745
FM02798
NC00224
(rs)-2-(diphenylmethylsulfinyl)acetamide
NCGC00095176-01
NCGC00095176-02
NCGC00095176-04
NCGC00095176-05
NCGC00095176-06
NCGC00095176-08
AS-17039
rac-2-((diphenylmethyl)sulfinyl)acetamide
SBI-0206841.P001
DB-116344
NS00003986
D01832
AB00639993_03
AB00639993_04
A836219
L001269
Q410441
SR-01000759419-3
SR-01000759419-4
BRD-A16332958-001-02-4
BRD-A16332958-001-04-0
BRD-A16332958-001-09-9
F2173-0797
Modafinil, European Pharmacopoeia (EP) Reference Standard
Modafinil for system suitability, European Pharmacopoeia (EP) Reference Standard
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