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Desloratadine

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Identification
Molecular formula
C19H19ClN2
CAS number
100643-71-8
IUPAC name
2-benzo[b][1]benzazepin-11-ylethanamine
State
State
Desloratadine is typically found as a solid at room temperature.
Melting point (Celsius)
150.00
Melting point (Kelvin)
423.20
Boiling point (Celsius)
465.30
Boiling point (Kelvin)
738.50
General information
Molecular weight
310.82g/mol
Molar mass
310.8210g/mol
Density
1.2350g/cm3
Appearence

Desloratadine appears as a white to off-white powder. It is freely soluble in methanol and slightly soluble in water.

Comment on solubility

Solubility of 2-benzo[b][1]benzazepin-11-ylethanamine

The solubility of 2-benzo[b][1]benzazepin-11-ylethanamine is a complex topic influenced by various factors. This compound, known for its intricate structure, showcases unique solubility characteristics that can be summarized as follows:

  • Polarity: With its multiple aromatic rings, the compound exhibits a degree of non-polarity, which typically results in low solubility in polar solvents such as water.
  • Solvent Compatibility: However, it tends to be more soluble in non-polar solvents such as chloroform or ethanol, where it can effectively interact with the solvent molecules.
  • pH Dependence: The solubility can also be affected by pH levels; as an amine, it may become more soluble in acidic conditions due to protonation.
  • Temperature Influence: Like many compounds, increasing the temperature generally enhances solubility, aiding in dissolving the solid form.

In summary, the solubility profile of 2-benzo[b][1]benzazepin-11-ylethanamine illustrates a distinctive balance between its structural properties and the characteristics of potential solvents. To quote a common principle in chemistry, "like dissolves like," emphasizing that achieving solubility often relies on matching the solvent to the compound's inherent properties.

Interesting facts

Interesting Facts about 2-benzo[b][1]benzazepin-11-ylethanamine

2-benzo[b][1]benzazepin-11-ylethanamine, a fascinating organic compound, belongs to a class of chemicals known for their diverse biological activities. Here are some engaging insights that illustrate its significance in the field of chemistry:

  • Structure & Stability: The compound features a complex polycyclic structure that includes a benzazepine ring. This intricate architecture contributes to its chemical stability and unique reactivity patterns.
  • Biological Relevance: Compounds like 2-benzo[b][1]benzazepin-11-ylethanamine have been explored for their potential therapeutic roles. Specifically, they may interact with neurotransmitter systems, making them of interest in pharmacological research.
  • Research Potential: Scientists are particularly intrigued by the potential of this compound in the development of new drugs targeting various neurological disorders. Investigation into its properties could lead to breakthroughs in treatment options.
  • Synthesis Challenges: The synthesis of such complex compounds involves advanced methodologies. Understanding the synthetic pathways can provide insight into reaction mechanisms and improve yields in the laboratory.
  • Interdisciplinary Links: Research on 2-benzo[b][1]benzazepin-11-ylethanamine often overlaps with fields such as medicinal chemistry, pharmacology, and even materials science, highlighting the interconnectedness of scientific disciplines.

In summary, 2-benzo[b][1]benzazepin-11-ylethanamine is not only noteworthy for its unique structural attributes but also for its significant implications in drug discovery and development. As research progresses, this compound may unveil new opportunities in enhancing human health.

Synonyms
5-(2-AMINOETHYL)-5H-DIBENZO(B,F)AZEPINE
2064-28-0
DTXSID20174676