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2-(Benzothiophen-3-yl)ethyl-dimethyl-ammonium chloride

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Identification
Molecular formula
C12H17ClNS
CAS number
71735-26-9
IUPAC name
2-(benzothiophen-3-yl)ethyl-dimethyl-ammonium;chloride
State
State

This compound exists in a solid state at room temperature. It is typically present in crystalline form and is stable under normal conditions.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.15
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.15
General information
Molecular weight
243.77g/mol
Molar mass
243.7740g/mol
Density
1.0400g/cm3
Appearence

2-(Benzothiophen-3-yl)ethyl-dimethyl-ammonium chloride appears as a white to slightly off-white crystalline powder. It is usually odorless or may have a slight characteristic smell.

Comment on solubility

Solubility of 2-(benzothiophen-3-yl)ethyl-dimethyl-ammonium;chloride

The solubility of 2-(benzothiophen-3-yl)ethyl-dimethyl-ammonium;chloride in various solvents is a crucial aspect to consider for both laboratory and industrial applications. This compound, being a quaternary ammonium salt, demonstrates specific solubility characteristics:

  • Water Solubility: Typically, quaternary ammonium salts exhibit moderate to high solubility in water. Due to the presence of the chloride counterion, which is quite soluble in water, one might expect this compound to also dissolve well in aqueous solutions.
  • Organic Solvents: When considering organic solvents, compounds such as ethanol, methanol, and acetone may offer varying degrees of solubility. The presence of the aromatic benzothiophen moiety can affect solubility in organic solvents significantly.
  • Solubility Trends: General trends suggest that:
    • Aromatic compounds tend to be less soluble in water but more soluble in organic solvents.
    • Alkyl chains can enhance solubility in non-polar solvents.

In summary, while the 2-(benzothiophen-3-yl)ethyl-dimethyl-ammonium;chloride salt may exhibit significant water solubility due to its ionic nature, its behavior in various organic solvents could reflect a more complex interaction influenced by its unique structure. Further experimental analysis is recommended to ascertain precise solubility values in different media, which is essential for practical applications.

Interesting facts

Interesting Facts about 2-(Benzothiophen-3-yl)ethyl-dimethyl-ammonium Chloride

This intriguing compound combines a benzothiophene structure with a quaternary ammonium ion, making it a subject of interest in both organic chemistry and medicinal chemistry. Here are some captivating insights:

  • Benzothiophene Connection: The benzothiophene ring system is known for its interesting electronic properties and is often incorporated into various pharmacologically active compounds.
  • Dimethyl Ammonium Ion: This ammonium group enhances the compound's solubility in water, which is crucial for its potential biological interactions.
  • Biological Activities: Compounds featuring quaternary ammonium ions, like this one, are often investigated for their antimicrobial properties and can serve as potential drug candidates in treating infections.
  • Application in Studies: The unique structure of this compound makes it valuable in medicinal chemistry research, particularly for the development of new therapeutic agents targeting neurological diseases.
  • Structure-Activity Relationship (SAR): Understanding how modifications to the benzothiophene and ammonium components impact biological activity can lead to the design of more effective pharmaceuticals.
  • Potential for Synthesis: The synthetic pathways leading to this compound employ various organic transformations that can be utilized in the laboratory to explore new chemical properties.

Ultimately, the compound 2-(benzothiophen-3-yl)ethyl-dimethyl-ammonium chloride epitomizes the intersection of chemical innovation and potential therapeutic application, solidifying its place as a compound of interest within the realm of chemistry.

Synonyms
N,N-Dimethylbenzo(b)thiophene-3-ethylamine hydrochloride
18648-22-1
N,N-Dimethyl-beta-3-aminoethylbenzothiophene hydrochloride
BENZO(b)THIOPHENE-3-ETHYLAMINE, N,N-DIMETHYL-, HYDROCHLORIDE