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Betahistine Hydrochloride

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Identification
Molecular formula
C8H15ClN2S
CAS number
5579-84-0
IUPAC name
2-(benzothiophene-2-carbonylamino)ethyl-diethyl-ammonium;chloride
State
State

At room temperature, Betahistine Hydrochloride is in a solid, crystalline state.

Melting point (Celsius)
148.00
Melting point (Kelvin)
421.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
278.82g/mol
Molar mass
278.8230g/mol
Density
1.2991g/cm3
Appearence

Betahistine Hydrochloride typically appears as a white or almost white crystalline powder. The compound is very hygroscopic, meaning it can easily absorb moisture from the air.

Comment on solubility

Solubility of 2-(benzothiophene-2-carbonylamino)ethyl-diethyl-ammonium;chloride

The solubility of 2-(benzothiophene-2-carbonylamino)ethyl-diethyl-ammonium;chloride can be quite intriguing due to the structural nature of the compound. This compound, containing both organic and ionic functional groups, influences its solubility characteristics significantly. Here are some key points to consider:

  • Ionic Nature: The presence of the ammonium group indicates that the compound is likely to be soluble in polar solvents, particularly water.
  • Organic Component: The benzothiophene moiety provides lipophilic characteristics, suggesting improved solubility in organic solvents.
  • Solvent Interaction: It is essential to consider the interaction between the solvent and solute molecules. The ability of the solvent to stabilize the ionic charge will enhance solubility.
  • Temperature Dependence: As with many compounds, solubility may increase with temperature, so higher temperatures might be beneficial for dissolving this compound.
  • pH Influence: The solubility can also be affected by pH. This compound may demonstrate varying solubility in acidic versus basic conditions due to potential ionization processes.

In summary, while the expected solubility of 2-(benzothiophene-2-carbonylamino)ethyl-diethyl-ammonium;chloride leans towards polar solvents, particularly water, its solubility profile may shift in the presence of varying environmental factors like temperature and pH. Understanding these nuances is crucial when working with this compound.

Interesting facts

Interesting Facts about 2-(benzothiophene-2-carbonylamino)ethyl-diethyl-ammonium;chloride

This compound, known as 2-(benzothiophene-2-carbonylamino)ethyl-diethyl-ammonium chloride, represents a fascinating intersection of organic chemistry and pharmacology. Here are some intriguing aspects:

  • Structural Complexity: The presence of a benzothiophene moiety in its structure adds considerable complexity. This aromatic compound is well-known for its diverse pharmacological activities, making it a valuable scaffold in medicinal chemistry.
  • Quaternary Ammonium Salt: As a diethylammonium salt, it exhibits unique properties typical of quaternary ammonium compounds, such as increased solubility and potential antimicrobial activity, which can be beneficial in various applications.
  • Potential Therapeutic Applications: Compounds of this nature can be explored for their utility in drug development, particularly in the design of agents targeting various diseases, including cancer and infectious diseases, owing to their complex structure that can interact with biological systems in novel ways.
  • Research Significance: Its unique combination of a carbonyl group and the benzothiophene core positions it as an interesting subject for studies on drug design and delivery mechanisms, both of which are crucial in developing effective therapeutics.
  • Synthesis Techniques: The synthesis of such compounds often involves sophisticated organic reactions, making them a perfect study for students interested in synthetic methodologies and reaction mechanisms in modern chemistry.

In summary, 2-(benzothiophene-2-carbonylamino)ethyl-diethyl-ammonium chloride exemplifies the intersection of organic chemistry and pharmacology, embodying promising therapeutic potential and challenging synthetic processes. This compound certainly deserves a place in the ongoing conversation about the future of medicinal compounds.

Synonyms
Macrogol 4000
NSC 108963
Macrogol 4000 [INN]
UNII-FZ46ONU496
Macrogol4000
BENZO(b)THIOPHENE-2-CARBOXAMIDE, N-(2-(DIETHYLAMINO)ETHYL)-, HYDROCHLORIDE
Benzo(b)thiophene-2-carboxamide, N-(2-(diethylamino)ethyl)-, monohydrochloride