Skip to main content

Pentamidine

ADVERTISEMENT
Identification
Molecular formula
C19H24N4
CAS number
100-33-4
IUPAC name
2-benzyl-1-(diaminomethylene)guanidine
State
State

At room temperature, pentamidine is a solid. It typically remains stable under ambient conditions if stored in a dry environment, away from light and moisture.

Melting point (Celsius)
191.00
Melting point (Kelvin)
464.15
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.15
General information
Molecular weight
340.43g/mol
Molar mass
340.4060g/mol
Density
1.5000g/cm3
Appearence

Pentamidine typically appears as a white to slightly yellow crystalline powder. It may have little to no odor, depending on its purity and form. The compound is generally stable and does not melt easily under normal conditions, making it suitable for prolonged storage.

Comment on solubility

Solubility of 2-benzyl-1-(diaminomethylene)guanidine

When examining the solubility of 2-benzyl-1-(diaminomethylene)guanidine, several factors come into play that can influence its behavior in different solvents. Typically, this compound exhibits a variable solubility profile in water, which can be attributed to its structural characteristics, particularly the presence of polar functional groups.

Key Points Regarding Solubility:

  • Hydrophilicity: The diaminomethylene group contributes to the hydrophilic nature of the compound, enhancing its solubility in polar solvents such as water.
  • Hydrophobic Interactions: The benzyl group introduces some hydrophobic characteristics, which may reduce solubility in strictly polar solvents.
  • Concentration Dependency: As with many organic compounds, solubility can increase with temperature, so heating may enhance its miscibility in solvents.
  • pH Sensitivity: The solubility of this compound might also vary with pH changes due to ionization of amino groups, leading to better solubility in acidic or basic environments.

In summary, the solubility of 2-benzyl-1-(diaminomethylene)guanidine in various solvents is a complex interplay between its structure and the nature of the solvent. Understanding these interactions is crucial for applications in biological systems or synthesis processes. As a general note, experimenting with varying conditions can provide a clearer picture of its solubility behavior.

Interesting facts

Interesting Facts About 2-benzyl-1-(diaminomethylene)guanidine

2-benzyl-1-(diaminomethylene)guanidine is a fascinating compound with a variety of interesting attributes and applications in the field of chemistry.

Key Characteristics and Applications

  • Pharmaceutical Importance: This compound has shown potential in medicinal chemistry, particularly in the development of drugs. Its structural similarity to certain biologically active molecules makes it a candidate for further research.
  • Versatile Reactivity: The presence of multiple functional groups allows for a variety of chemical reactions, making it a useful building block in organic synthesis.
  • Research Relevance: Researchers are exploring its effects on enzymatic activity and its ability to act as an inhibitor in biochemical pathways, which could lead to advances in treating diseases.

Chemical Structure Insights

The structure of 2-benzyl-1-(diaminomethylene)guanidine is marked by:

  • A guanidine functional group, which typically exhibits strong basicity and can interact with acids or nucleophiles.
  • A benzyl group that may enhance lipophilicity, improving interaction with biological membranes.

Quotes From Researchers

As one researcher noted, "The unique combination of guanidine and benzyl moieties in this compound opens up exciting avenues for exploration in both synthetic and medicinal chemistry."

Future Directions

Continuing studies on 2-benzyl-1-(diaminomethylene)guanidine are essential, with a focus on:

  • Understanding its mechanism of action and potential therapeutic effects.
  • Exploring modifications of its structure to enhance its biological activity.

This compound exemplifies the intricate interplay between structure and function in organic chemistry, and underscores the importance of innovative research in the development of new therapeutic agents.

Synonyms
2-benzyl-1-(diaminomethylidene)guanidine
18030-95-0
DTXSID00274547
DTXCID40226020
Imidodicarbonimidic diamide, N-(phenylmethyl)-
CHEMBL3628706
N-BENZYLIMIDODICARBONIMIDIC DIAMIDE
N-(Phenylmethyl)imidodicarbonimidic diamide
1-benzylbiguanide
benzyldiguanide
Benzylbiguanid
N'-Benzylbiguanide
starbld0009797
1-BENZYL-BIGUANID
ChemDiv3_000075
SCHEMBL1520136
SCHEMBL8348755
T25K4Y63E9
BDBM50227351
AKOS032961326
AKOS040827258
IDI1_019393
N-benzyl-1-carbamimidamidomethanimidamide
G81110
1-benzyl-biguanide; N-Benzyl-biguanid; N-Benzyl-N'-guanyl-guanidin