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2-Benzyl-1,3-dicyclohexylguanidine

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Identification
Molecular formula
C20H33N3
CAS number
52311-99-6
IUPAC name
2-benzyl-1,3-dicyclohexyl-guanidine
State
State

At room temperature, 2-benzyl-1,3-dicyclohexylguanidine is a solid, typically found as a crystalline solid or powder form.

Melting point (Celsius)
123.50
Melting point (Kelvin)
396.65
Boiling point (Celsius)
451.90
Boiling point (Kelvin)
725.05
General information
Molecular weight
334.52g/mol
Molar mass
334.5210g/mol
Density
1.0360g/cm3
Appearence

2-Benzyl-1,3-dicyclohexylguanidine typically appears as a white crystalline solid. It may display a slight yellowish tint due to impurities or prolonged exposure to air.

Comment on solubility

Solubility of 2-benzyl-1,3-dicyclohexyl-guanidine

When evaluating the solubility of 2-benzyl-1,3-dicyclohexyl-guanidine, several factors come into play that dictate how this compound interacts with various solvents. As an organic guanidine, it exhibits certain distinctive solubility characteristics.

Key Points on Solubility:

  • Polar vs. Nonpolar Solvents: Due to the presence of cyclohexyl and benzyl groups, this compound tends to have limited solubility in polar solvents such as water, while it may show better solubility in nonpolar solvents.
  • Hydrophobic Characteristics: The hydrophobic nature of the dicyclohexyl moiety contributes to reduced interactions with water, influencing its ability to dissolve in aqueous solutions.
  • Temperature Effects: Like many organic compounds, its solubility may increase with temperature, making hot organic solvents potentially more effective for dissolving this compound.

In summary, 2-benzyl-1,3-dicyclohexyl-guanidine showcases solubility properties that align with its structural features. It is important to consider the solvent choice carefully for effective dissolution, as the polarity of the solvent significantly impacts the overall solubility behavior.

Interesting facts

Interesting Facts about 2-benzyl-1,3-dicyclohexyl-guanidine

2-benzyl-1,3-dicyclohexyl-guanidine is an intriguing organic compound with unique properties and applications. Here are some fascinating insights:

  • Pharmaceutical Applications: This compound is often studied for its potential as a therapeutic agent, particularly in the field of neuroscience. Its structure allows it to interact favorably with biological targets.
  • Selective Binding: The guanidine group in its structure enables selective binding to specific receptors, which enhances its effectiveness in various medicinal applications.
  • Modifying Activity: Researchers often explore ways to modify the side chains, such as the benzyl and dicyclohexyl groups, which can significantly influence the compound's biological activity and pharmacokinetics.
  • Mechanism of Action: Investigations into the mechanism of action of this compound reveal interesting pathways that may lead to new treatments for neurological disorders.
  • Importance of Chirality: The presence of multiple cyclic structures introduces chirality, which plays a crucial role in the compound's interaction with biological systems. This aspect opens doors for developing enantiomerically pure forms to optimize therapeutic efficacy.

In summary, 2-benzyl-1,3-dicyclohexyl-guanidine combines a rich chemical structure with promising pharmacological potential, making it a subject of keen interest in medicinal chemistry research.

Synonyms
SCHEMBL7598627
SCHEMBL17187551
SCHEMBL19435743