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2-Benzyl-1H-benzimidazole

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Identification
Molecular formula
C14H12N2
CAS number
621-72-7
IUPAC name
2-benzyl-1H-benzimidazole
State
State

At room temperature, 2-Benzyl-1H-benzimidazole is a solid. It is usually handled in powder or crystalline form for ease of use in various applications, including in research and chemical synthesis.

Melting point (Celsius)
176.00
Melting point (Kelvin)
449.20
Boiling point (Celsius)
471.40
Boiling point (Kelvin)
744.50
General information
Molecular weight
222.26g/mol
Molar mass
222.2780g/mol
Density
1.2060g/cm3
Appearence

2-Benzyl-1H-benzimidazole typically appears as a white to off-white crystalline powder. Its appearance may vary slightly depending on the level of purity and specific synthesis methods used, but it generally maintains a consistent crystalline structure.

Comment on solubility

Solubility of 2-benzyl-1H-benzimidazole

2-benzyl-1H-benzimidazole, a compound with intriguing properties, exhibits unique solubility characteristics that can vary based on environmental factors. Generally, this compound is regarded as:

  • Moderately soluble in organic solvents such as ethanol and dichloromethane.
  • Poorly soluble in water, which can limit its application in aqueous environments.

These solubility traits can largely be attributed to its nonpolar aromatic structure. When discussing solubility, it's important to consider:

  1. The polarity of the solvent being used.
  2. The temperature of the solution, as higher temperatures often enhance solubility.
  3. The presence of functional groups that can influence intermolecular interactions.

Understanding the solubility of 2-benzyl-1H-benzimidazole is crucial for its effective use in various chemical applications, pharmaceuticals, and research settings. As the saying goes, "Like dissolves like," and selecting the appropriate solvent is key to optimizing its performance in formulations.

Interesting facts

Interesting Facts about 2-benzyl-1H-benzimidazole

2-benzyl-1H-benzimidazole is a fascinating compound that bridges the realms of organic chemistry and medicinal applications. Here are some intriguing aspects of this compound:

  • Structural Complexity: The name "2-benzyl-1H-benzimidazole" reflects its intricate structure, featuring a fused benzene and imidazole ring system. This structural configuration contributes to its unique chemical reactivity and potential biological activity.
  • Biological Significance: Compounds containing a benzimidazole core are often known for their diverse biological activities. They have been studied for their potential effects on various diseases, including cancer and parasitic infections.
  • Versatile Applications: Beyond pharmaceuticals, derivatives of benzimidazole, including 2-benzyl-1H-benzimidazole, find applications in agriculture as fungicides and in materials science due to their ability to form conductive polymers.
  • Synthetic Pathways: The synthesis of this compound typically involves multi-step reactions, allowing chemists to explore various reaction conditions and catalysts to optimize yields and purity.
  • Intriguing Properties: The diverse electronic properties of the benzyl and imidazole moieties enhance the compound's stability and reactivity, making it an interesting subject for theoretical studies and computational chemistry.

As emphasized by many researchers, "the journey of discovery is often as fascinating as the destination." Studying 2-benzyl-1H-benzimidazole opens up a world of possibilities in understanding complex biological mechanisms and developing new therapeutic agents.


Synonyms
Bendazol
2-Benzyl-1H-benzimidazole
Dibazole
Bendazole
Tromasedan
2-Benzylbenziminazole
Bendazol [INN:DCF]
BENZIMIDAZOLE, 2-BENZYL-
Bendazolo [DCIT]
Bendazolo
Bendazolum
1H-Benzimidazole, 2-(phenylmethyl)-
2-(Phenylmethyl)-1H-benzimidazole
Bendazolum [INN-Latin]
NSC 60020
EINECS 210-703-6
NSC-60020
Bendazol (INN)
UNII-26601THN1D
BRN 0159495
BENDAZOL [INN]
BENDAZOL [MI]
BENDAZOL [WHO-DD]
DTXSID80211157
5-23-08-00498 (Beilstein Handbook Reference)
Bendazolum (INN-Latin)
Dibasole
dibazolum (for the hydrochloride)
DTXCID80133648
1H-Benzimidazole, 2-(phenylmethyl)-(9CI)
210-703-6
ytlqfzvclxffrk-uhfffaoysa-n
621-72-7
2-Benzylbenzimidazole
2-Benzyl-1H-benzo[d]imidazole
2-Benzyl-1H-benzoimidazole
Dibazol
Dibasol
2-Benzyl-1H-1,3-Benzodiazole
26601THN1D
NSC631632
SMR000514120
Dibazol (TN)
MFCD00022680
Enamine_004617
Oprea1_667015
Oprea1_810669
MLS001212883
MLS001240258
2-Benzyl-1H-benzimidazole #
Bendazol;2-Benzylbenzimidazole
SCHEMBL309393
CHEMBL355063
CHEBI:134876
HMS1407B19
HMS2234P09
HMS3373C18
2-BENZYLBENZIMIDAZOLE,TECH.
ALBB-016070
BCP22654
HY-B2141
NSC60020
BBL010591
BDBM50404901
s3589
STK298846
AKOS000275564
CS-8010
DS-3426
FB39600
NSC-631632
NCGC00245123-01
AC-16125
AC-32030
DB-054083
NS00034949
EN300-04389
A10833
D07504
AB00277645-07
AF-615/00098050
SR-01000787186
Q4083689
SR-01000787186-3
BRD-K60379054-001-07-0
Z55692912
F0037-5472