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2-Benzyl-6-nitrobenzimidazole

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Identification
Molecular formula
C14H11N3O2
CAS number
39023-50-8
IUPAC name
2-benzyl-6-nitro-1H-benzimidazole
State
State

At room temperature, 2-Benzyl-6-nitrobenzimidazole is in a solid state, typically found as a crystalline powder.

Melting point (Celsius)
222.00
Melting point (Kelvin)
495.15
Boiling point (Celsius)
475.00
Boiling point (Kelvin)
748.15
General information
Molecular weight
281.26g/mol
Molar mass
281.2890g/mol
Density
1.3625g/cm3
Appearence

2-Benzyl-6-nitrobenzimidazole appears as a pale yellow crystalline powder. It is commonly used in various chemical research applications due to its distinct structural properties.

Comment on solubility

Solubility of 2-benzyl-6-nitro-1H-benzimidazole

When examining the solubility of 2-benzyl-6-nitro-1H-benzimidazole, it is important to note the influence of its functional groups and structural characteristics. This compound presents a complex aromatic system that can affect its interaction with solvents.

Factors Influencing Solubility:

  • Aromatic Structure: The presence of multiple aromatic rings may render the compound relatively insoluble in water due to π-π stacking interactions.
  • Polar Functional Groups: The nitro group (-NO2) introduces polar characteristics that can enhance solubility in polar solvents.
  • Hydrophobic Effects: The benzyl group contributes hydrophobic properties, potentially limiting water solubility but increasing compatibility with organic solvents.

In summary, while 2-benzyl-6-nitro-1H-benzimidazole is expected to have limited solubility in water, it may demonstrate increased solubility in organic solvents such as ethanol or dichloromethane. As with many chemical compounds, **the specific solvent conditions** can significantly impact its solubility.

Interesting facts

Interesting Facts about 2-benzyl-6-nitro-1H-benzimidazole

2-benzyl-6-nitro-1H-benzimidazole is a fascinating compound belonging to the benzimidazole class, notable for its diverse biological and chemical applications. Here are some key points that highlight its significance:

  • Pharmaceutical Potential: This compound exhibits promising antibacterial and antifungal activities, making it a subject of interest for medicinal chemistry. Researchers are examining its efficacy as a drug candidate against various pathogens.
  • Structure and Stability: The nitro group and the benzyl moiety contribute to the compound's stability and reactivity, allowing valuable modifications in synthetic processes, which is essential for developing new derivatives with enhanced properties.
  • Role in Organic Chemistry: 2-benzyl-6-nitro-1H-benzimidazole serves as an important building block in the synthesis of more complex organic molecules, demonstrating its versatility in synthetic routes.
  • Research Applications: Its unique structure is not only crucial for theoretical studies in chemogenomics but also aids in computer-aided drug design (CADD) to discover novel therapeutics more efficiently.

As one delves deeper into the realm of organic compounds, the potential of 2-benzyl-6-nitro-1H-benzimidazole continually unfolds, offering a wealth of opportunities for innovation in chemical research and drug development.

"The beauty of chemistry lies in its complexity and the endless possibilities it presents." – A reminder of the importance of compounds like this in the quest for knowledge and advancement.

Synonyms
2-Benzyl-5-nitro-1H-benzimidazole
7189-72-2
CHEMBL4077039
2-Benzyl-5-nitro-benzimidazole
Benzyl-2 nitro-5 benzimidazole [French]
2-benzyl-6-nitro-1H-benzimidazole
BENZIMIDAZOLE, 2-BENZYL-5-NITRO-
Benzyl-2 nitro-5 benzimidazole
Oprea1_331428
2-Benzyl-5-nitrobenzimidazole
5-nitro-2-benzylbenzimidazole
SCHEMBL6763997
DTXSID20992599
UMWIVOZCYNITGG-UHFFFAOYSA-N
BDBM50244670
AKOS002678173
EJY