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2-Benzylguanidine

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Identification
Molecular formula
C8H11N3
CAS number
1113-97-7
IUPAC name
2-benzylguanidine
State
State

At room temperature, 2-benzylguanidine is typically in a solid state. It is easily handled and stored in this form, making it convenient for various chemical applications.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
344.00
Boiling point (Kelvin)
617.15
General information
Molecular weight
163.19g/mol
Molar mass
163.2190g/mol
Density
1.2000g/cm3
Appearence

2-Benzylguanidine appears as a white crystalline solid. It is usually provided as a powder and has a characteristic aromatic odor. The compound is stable under normal temperatures and pressures but should be kept away from strong oxidizing agents.

Comment on solubility

Solubility of 2-benzylguanidine

2-benzylguanidine, with its unique structure, shows distinct solubility characteristics that are important for its applications in chemical and biochemical environments. Understanding its solubility helps researchers and chemists predict how it will behave in various solvents.


Key points about the solubility of 2-benzylguanidine include:

  • Polar Solvents: 2-benzylguanidine tends to be soluble in polar solvents such as water and alcohols. This property can be attributed to strong intermolecular interactions, including hydrogen bonding.
  • Impurities Effect: The presence of impurities can significantly affect solubility. As impurities may alter solvent properties, they can enhance or reduce the solubility of the compound.
  • pH Influence: The solubility of 2-benzylguanidine can also be affected by pH levels. In acidic or basic conditions, the ionization state may change, thereby influencing its solubility in aqueous solutions.

As a valuable insight, understanding the solubility of 2-benzylguanidine is crucial for its utilization in various chemical syntheses and pharmaceutical applications. Researchers often quote that "solubility is king" when it comes to drug formulation, highlighting the critical need to explore these characteristics thoroughly.

Interesting facts

Interesting Facts About 2-benzylguanidine

2-benzylguanidine is an intriguing chemical compound belonging to the family of guanidines, which are known for their significant biological activity. This compound exhibits various properties that make it a subject of interest for scientists and researchers in multiple fields.

Biological Significance

  • Antidepressant Effects: Research has indicated that 2-benzylguanidine may have potential antidepressant properties, which could lead to novel therapeutic approaches for mood disorders.
  • Targeting Cancer Cells: This compound has shown promise in selectively targeting certain cancer cell types, particularly neuroendocrine tumors. Its ability to interact with cellular mechanisms is vital in developing cancer treatment.

Chemical Characteristics

One interesting feature of 2-benzylguanidine is its unique structure. The presence of the benzyl group enhances its lipophilicity, allowing it to cross cellular membranes more effectively compared to other guanidine derivatives. This property is quite useful in pharmacological applications.

Applications in Research

  • Neuropharmacological Studies: It is often used in pharmacological studies to elucidate mechanisms behind neurotransmitter regulation.
  • Diagnostic Tool: 2-benzylguanidine can serve as a molecular probe in diagnosis, particularly in imaging techniques that target specific receptor sites.

Quote from the Literature

In the words of a renowned chemist, "Understanding compounds like 2-benzylguanidine not only hones our knowledge of chemistry but also opens doors to potential breakthroughs in medicine."

Overall, 2-benzylguanidine stands out as a vital compound that bridges the gap between organic chemistry and medicinal applications, showcasing the profound impact chemical compounds can have on health and disease.

Synonyms
1-Benzylguanidine
N-Benzylguanidine
2211-57-6
Benzylguanidine
N-Benzoguanidine
GUANIDINE, BENZYL-
Guanidine, (phenylmethyl)-
G6537F6GQS
NSC 227970
NSC-227970
DTXSID20944755
DTXCID801021287
Guanidine, (phenylmethyl)-(9CI)
2-benzylguanidine
N-Benzyl-guanidine
CHEMBL288640
C8H11N3
monobenzylguanidine
1-benzyl-guanidine
UNII-G6537F6GQS
SCHEMBL45768
ABSNGNUGFQIDDO-UHFFFAOYSA-N
ALBB-005187
BCP31403
BDBM50013044
MFCD00461648
NSC227970
STK501305
AKOS000321591
FB13909
s12114
AS-54562
SY074251
CS-0139507
EN300-73529
Guanidine,N-(phenylmethyl)-;1-Benzylguanidine;N-Benzylguanidine;Benzylguanidine