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2-Benzyloxycarbonylbenzoic acid

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Identification
Molecular formula
C15H12O4
CAS number
1947-56-6
IUPAC name
2-benzyloxycarbonylbenzoic acid
State
State

At room temperature, 2-benzyloxycarbonylbenzoic acid is a solid. It holds a crystalline form suitable for laboratory storage and handling.

Melting point (Celsius)
90.00
Melting point (Kelvin)
363.15
Boiling point (Celsius)
402.30
Boiling point (Kelvin)
675.50
General information
Molecular weight
256.27g/mol
Molar mass
256.2660g/mol
Density
1.3240g/cm3
Appearence

2-Benzyloxycarbonylbenzoic acid is typically encountered as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-Benzyloxycarbonylbenzoic Acid

2-Benzyloxycarbonylbenzoic acid, known for its intriguing structure, exhibits specific solubility characteristics worth noting. This compound is primarily characterized by its minimal water solubility, which can be attributed to its relatively large and bulky organic structure. The *functional groups* present interplay significantly with solvation processes.

Solubility Characteristics:

  • Solvent Preference: 2-Benzyloxycarbonylbenzoic acid tends to dissolve more readily in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO) compared to aqueous environments.
  • Water Solubility: Due to its hydrophobic components, the solubility in water is quite low, making it less favorable for applications requiring high aqueous stability.
  • Influence of Temperature: Like many organic compounds, increasing the temperature can enhance solubility in organic solvents.

The practical implications of this solubility behavior are significant in both laboratory and industrial contexts, often guiding the choice of solvent in chemical reactions and extractions involving 2-benzyloxycarbonylbenzoic acid. Understanding solubility is crucial for achieving optimal results in synthesis and formulation.

Interesting facts

Interesting Facts about 2-Benzyloxycarbonylbenzoic Acid

2-Benzyloxycarbonylbenzoic acid is a fascinating compound in organic chemistry, noteworthy for its unique structure and diverse applications. Here are some intriguing aspects of this compound:

  • Structure and Functionality: The compound features a benzyloxycarbonyl group, which is a common protective group for amino acids. This makes it valuable in the realm of peptide synthesis and other organic transformations.
  • Role in Peptide Chemistry: Due to its functionality, 2-benzyloxycarbonylbenzoic acid is often utilized as a precursor in the synthesis of various peptides. This is particularly significant for creating bioactive compounds in pharmaceutical research.
  • Applications in Drug Development: The protective group associated with this acid allows for selective reactions, making it an essential building block in the design of new drugs. The ability to manipulate the molecule opens doors to novel therapeutic agents.
  • Research Interest: Scientists are continually drawn to this compound for its reactivity and versatility. Research often focuses on optimizing reaction conditions to enhance yields and minimize side reactions, a crucial aspect of synthetic organic chemistry.
  • Theoretical Significance: The study of 2-benzyloxycarbonylbenzoic acid also provides insights into reaction mechanisms and kinetics, making it a valuable subject for both undergraduate students and advanced researchers.

In the words of one renowned chemist, “The beauty of organic synthesis lies in its endless possibility to create and manipulate nature’s building blocks.” The exploration of compounds like 2-benzyloxycarbonylbenzoic acid exemplifies this sentiment, highlighting the creativity and innovation inherent in chemical science.

Synonyms
Monobenzyl phthalate
2528-16-7
Phthalic Acid Monobenzyl Ester
Mono-benzyl phthalate
Benzyl hydrogen phthalate
Mono-n-benzyl phthalate
2-phenylmethoxycarbonylbenzoic acid
Phthalic acid, benzyl ester
1,2-Benzenedicarboxylic acid, mono(phenylmethyl) ester
DTXSID9043938
Mono(phenylmethyl) 1,2-benzenedicarboxylate
27NM8BNV1K
NSC-402008
DTXCID7023938
CHEBI:132612
1,2-Benzenedicarboxylic acid, 1-(phenylmethyl) ester
RefChem:819267
219-771-1
2-((Benzyloxy)carbonyl)benzoic acid
2-[(Benzyloxy)carbonyl]benzoic acid
MFCD00020279
2-benzyloxycarbonylbenzoic acid
Phthalic acid, mono-benzyl ester
Benzene-1,2-dicarboxylic acid, mono(phenylmethyl) ester
Benzene-1,2-dicarboxylic acid, monobenzyl ester
2-[benzyloxycarbonyl]benzoic acid
Phthalic acid, mono-benzyl ester 100 microg/mL in Methyl-tert-butyl ether
NSC 402008
EINECS 219-771-1
UNII-27NM8BNV1K
BzBP
MBeP
1,2-Benzenedicarboxylic acid, mono(phenylmethyl) ester (9CI); Phthalic acid, benzyl ester (6CI,7CI,8CI); 2-[(Benzyloxy)carbonyl]benzoic acid; Benzyl hydrogen phthalate; Monobenzyl phthalate; NSC 402008
mono benzyl phthalate
ChemDiv3_000594
BENZYLHYDROGENPHTHALAT
monobenzyl phthalate (mbzp)
1, mono(phenylmethyl) ester
BIDD:PXR0040
CBDivE_003018
MLS000104449
SCHEMBL116566
1,2-Benzenedicarboxylic Acid 1-(Phenylmethyl) Ester
orb1310455
Monobenzyl phthalate (Standard)
CHEMBL1466083
SCHEMBL29687907
o-(benzyloxycarbonyl)benzoic acid
MSK1145
HMS1474K22
HMS2300N14
2-((Benzyloxy)carbonyl)benzoicacid
HY-W011848R
Tox21_300626
NSC402008
STK524189
XH1172
AKOS001570006
2-[(Benzyloxy)carbonyl]benzoic acid #
BENZYLHYDROGENPHTHALAT [WHO-DD]
CS-W012564
HY-W011848
NCGC00080394-02
NCGC00254352-01
AS-47938
mono-Benzyl phthalate, analytical standard
SMR000054384
ST037064
SY053700
CAS-2528-16-7
DB-046661
ST4012661
NS00010913
P1191
F17052
AG-205/40012187
SR-01000399402
SR-01000399402-1
BRD-K83275418-001-01-7
Q26840961