Skip to main content

(2-benzyloxyphenyl)methanol

ADVERTISEMENT
Identification
Molecular formula
C14H14O2
CAS number
15861-24-2
IUPAC name
(2-benzyloxyphenyl)methanol
State
State

At room temperature, (2-benzyloxyphenyl)methanol is generally found in a solid state, often prepared and handled as a crystalline powder for industrial and research purposes.

Melting point (Celsius)
42.00
Melting point (Kelvin)
315.20
Boiling point (Celsius)
357.50
Boiling point (Kelvin)
630.70
General information
Molecular weight
214.26g/mol
Molar mass
214.2580g/mol
Density
1.1390g/cm3
Appearence

(2-Benzyloxyphenyl)methanol typically appears as a colorless to pale yellow solid at room temperature. It may also be found as a crystalline powder or a semi-solid, depending on purity and storage conditions. When impure, it could exhibit slight coloration due to oxidized or degraded products.

Comment on solubility

Solubility of (2-benzyloxyphenyl)methanol

The solubility of (2-benzyloxyphenyl)methanol in various solvents can provide valuable insights into its chemical behavior and potential applications. This compound is primarily characterized by its aromatic structure combined with a methanol group, which influences its interaction with solvents.

Solubility Insights:

  • Polar Solvents: (2-benzyloxyphenyl)methanol is expected to be soluble in polar solvents such as water and ethanol. The hydroxyl group (-OH) enhances its affinity for polar environments.
  • Nonpolar Solvents: In contrast, its solubility in nonpolar solvents, such as hexane or chloroform, may be limited due to the inability of the compound to effectively interact with the hydrophobic characteristics of these solvents.
  • Temperature Dependence: The solubility can also vary significantly with temperature changes, often increasing with higher temperatures, which allows for greater solvent interaction and potential dissolution of the compound.

This solubility behavior can be summarized by the principle that "like dissolves like"—where polar compounds tend to dissolve in polar solvents, and nonpolar compounds in nonpolar solvents. This understanding is critical when considering the use of (2-benzyloxyphenyl)methanol in both laboratory and industrial contexts, as proper solvent selection can enhance extraction processes and reactions.

Interesting facts

Interesting Facts about (2-Benzyloxyphenyl)methanol

(2-Benzyloxyphenyl)methanol is a fascinating compound that plays a significant role in various chemical and biological applications. Here are some intriguing aspects of this compound:

  • Structural Significance: The compound features a unique benzyloxy group, which can influence its reactivity and stability, making it a valuable subject of study in organic synthesis.
  • Natural Product Analogs: (2-Benzyloxyphenyl)methanol is often utilized in the development of natural product analogs, expanding the horizon for drug discovery and medicinal chemistry.
  • Research Applications: Scientists have explored this compound in the context of its antioxidant properties, looking into its potential health benefits, which adds to its desirability in pharmaceutical research.
  • Mechanism Studies: It serves as an excellent model compound for understanding the mechanisms of various chemical reactions due to its distinct functional groups, allowing chemists to probe deeper into reaction pathways.
  • Versatile Synthesis: The synthesis of (2-Benzyloxyphenyl)methanol can often involve various methodologies, including Friedel-Crafts alkylation and leveraging coupling reactions, showcasing the diversity of synthetic organic chemistry.

Cultural and Educational Relevance

This compound is not only important for empirical research but also offers educational value for students learning organic chemistry. Engaging in synthesizing (2-Benzyloxyphenyl)methanol can provide hands-on experience with nucleophilic substitution reactions and the importance of functional group manipulation. It exemplifies essential principles, including structure-activity relationships that are fundamental in the field of drug design.

In summary, (2-Benzyloxyphenyl)methanol is more than just a chemical entity; it represents a confluence of versatility in synthetic applications, potential in medicinal chemistry, and educational opportunities for aspiring chemists.

Synonyms
2-Benzyloxybenzyl alcohol
3381-87-1
(2-(Benzyloxy)phenyl)methanol
Benzyl ether of saligenin
[2-(Benzyloxy)phenyl]methanol
Benzenemethanol, 2-(phenylmethoxy)-
2-(Phenylmethoxy)benzenemethanol
BENZYL ALCOHOL, o-(BENZYLOXY)-
BRN 2212681
DTXSID50187471
DTXCID60109962
Benzenemethanol, 2-(phenylmethoxy)-(9CI)
630-896-4
(2-phenylmethoxyphenyl)methanol
2-(benzyloxy)benzyl alcohol
MFCD01664428
Benzenemethanol, 2-(phenylmethoxy)- (9CI)
MLS003675150
SCHEMBL692555
Benzyl alcohol,o-(benzyloxy)-
97BD6L3N4P
[2-(Benzyloxy)phenyl]methanol #
AKOS000125307
AS-44397
Benzenemethanol,2-(phenylmethoxy)-(9CI,
SMR001490975
B2943
CS-0196084
EN300-139256