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Chloroethylclonidine

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Identification
Molecular formula
C6H11Cl2NO2
CAS number
3081-46-5
IUPAC name
2-[bis(2-chloroethyl)amino]acetic acid
State
State
Solid at room temperature.
Melting point (Celsius)
52.00
Melting point (Kelvin)
325.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
222.06g/mol
Molar mass
222.0560g/mol
Density
1.3420g/cm3
Appearence

2-[bis(2-chloroethyl)amino]acetic acid is a solid compound at room temperature. It typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-[bis(2-chloroethyl)amino]acetic acid

2-[bis(2-chloroethyl)amino]acetic acid is a unique compound that presents interesting solubility characteristics. Its solubility can be influenced by several factors, including:

  • Polarity: Due to the presence of both amine and carboxylic acid functional groups, the compound exhibits polar characteristics, which generally enhance its solubility in polar solvents such as water.
  • Temperature: As is typical with many organic compounds, increasing the temperature can lead to higher solubility. Warm water or organic solvents may facilitate dissolving the compound more efficiently.
  • pH Levels: The solubility of 2-[bis(2-chloroethyl)amino]acetic acid can also be affected by the pH of the solution. In more alkaline conditions, the carboxylic acid group may become deprotonated, increasing solubility.

In general, you may find the compound moderately soluble in aqueous solutions and various organic solvents. Practically, the solubility behavior can be summed up as:

  1. Soluble in polar solvents
  2. Solubility increases with temperature
  3. Alkaline conditions enhance solubility

To quote a common observation in chemistry, "like dissolves like," which perfectly captures the essence of the solubility behavior of 2-[bis(2-chloroethyl)amino]acetic acid. Understanding these solubility traits is crucial for effectively utilizing this compound in various applications.

Interesting facts

Interesting Facts about 2-[bis(2-chloroethyl)amino]acetic acid

2-[bis(2-chloroethyl)amino]acetic acid, commonly known in certain circles for its unique properties and potential applications, is a fascinating compound that has drawn attention in various fields, including medicinal chemistry and chemical biology. Here are some intriguing insights about this compound:

  • Cytotoxic Properties: This compound exhibits cytotoxic effects, particularly against certain types of cancer cells. It has been studied for its potential use in chemotherapy regimens.
  • Mechanism of Action: As an alkylating agent, 2-[bis(2-chloroethyl)amino]acetic acid can modify DNA, leading to apoptosis (programmed cell death) in vulnerable cells. This mechanism is vital in the fight against cancer.
  • Synthesis Routes: The synthesis of this compound can be achieved through various pathways, incorporating reactions like nucleophilic substitutions, which allow chemists to explore different approaches to producing effective pharmaceuticals.
  • Research and Development: Ongoing research on this compound includes optimizing its structure to enhance efficacy while reducing potential side effects. The balance between activity and toxicity is a critical focus.
  • Historical Significance: Compounds similar to 2-[bis(2-chloroethyl)amino]acetic acid have a history of use as chemical warfare agents, highlighting the dual nature of chemical substances and the ethical considerations in their applications.

As scientists continue to investigate 2-[bis(2-chloroethyl)amino]acetic acid, new discoveries may lead to breakthroughs in targeted therapies and innovative treatment modalities. Its journey in the realm of science exemplifies the complexity and promise of chemical compounds in addressing human health challenges.

Synonyms
N,N-Bis(2-chloroethyl)glycine
GLYCINE, N,N-BIS(2-CHLOROETHYL)-
98486-41-0
BRN 1769473
DTXSID70243583
4-04-00-02374 (Beilstein Handbook Reference)
DTXCID00166074
SCHEMBL10522896