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Glyphosine

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Identification
Molecular formula
C4H10NO7P2
CAS number
4418-26-2
IUPAC name
2-[bis(phosphonomethyl)amino]acetic acid
State
State

At room temperature, glyphosine is typically found in a solid powdered form. It is stable under normal conditions, but like many phosphonic acids, it may decompose when exposed to higher temperatures or acidic/basic environments.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
255.10g/mol
Molar mass
255.0990g/mol
Density
1.4800g/cm3
Appearence

Glyphosine typically appears as a solid crystalline powder. It is generally a colorless to pale yellow compound, and it may exhibit slight hygroscopic properties, meaning it can absorb moisture from the air, affecting its appearance.

Comment on solubility

Solubility of 2-[bis(phosphonomethyl)amino]acetic acid

2-[bis(phosphonomethyl)amino]acetic acid is notable for its unique solubility characteristics, making it an interesting compound to study. Its solubility is primarily influenced by several factors:

  • Polarity: This compound is highly polar due to the presence of multiple functional groups, such as phosphonic acid moieties and amino groups, which facilitate hydrogen bonding and ionic interactions.
  • pH Dependency: The solubility can change significantly with pH. In acidic conditions, it tends to be more soluble due to the protonation of the amino groups, enhancing its ability to interact with water.
  • Concentration: Like many amino acids and their derivatives, solubility can be concentration-dependent; higher concentrations may lead to precipitation at certain conditions.
  • Temperature: Elevated temperatures often increase solubility, as higher thermal energy can disrupt intermolecular interactions.

The general consensus is that 2-[bis(phosphonomethyl)amino]acetic acid is highly soluble in water, particularly in neutral to acidic environments. However, solubility decreases in more alkaline conditions where the overall ionic character diminishes. As emphasized by researchers, “the ability to solubilize this compound under various pH conditions makes it invaluable in industrial applications and biochemical research.”

In conclusion, understanding the solubility of 2-[bis(phosphonomethyl)amino]acetic acid is crucial for its practical applications in various fields, providing insight into its chemical behavior and potential uses.

Interesting facts

Interesting Facts about 2-[bis(phosphonomethyl)amino]acetic acid

2-[bis(phosphonomethyl)amino]acetic acid, often referred to as a member of the phosphonic acid family, is a fascinating compound that attracts attention for its unique properties and applications. Here are some engaging insights:

  • Biochemical Importance: This compound plays a critical role in biochemistry, particularly in the synthesis of phosphonates which mimic biological molecules. Its structural similarity to amino acids allows it to interact with various biological systems.
  • Potential Therapeutic Applications: Due to its ability to modulate biological pathways, 2-[bis(phosphonomethyl)amino]acetic acid has been studied for its potential use in pharmaceuticals, particularly as a treatment for various diseases that involve dysregulated phosphonate metabolism.
  • Environmental Significance: This compound's efficacy as a chelating agent makes it a valuable resource in environmental chemistry. It can bind to heavy metals, potentially aiding in the remediation of contaminated sites.
  • Agricultural Use: Researchers are exploring its utility in agriculture, where it may function as a herbicide or fungicide, providing a more environmentally friendly approach to pest control compared to traditional chemicals.
  • Research and Development: The synthesis of 2-[bis(phosphonomethyl)amino]acetic acid has become a subject of interest in material science, where it contributes to the development of innovative compounds with tailored reactivity and selectivity for specific applications.

In summary, 2-[bis(phosphonomethyl)amino]acetic acid is more than just a chemical compound; it opens the door to numerous scientific explorations and potential breakthroughs in medicine, environmental science, and agriculture. Its diverse applications highlight the significance of assessing the chemical properties of compounds and their interactions within biological and ecological systems.

Synonyms
GLYPHOSINE
2439-99-8
Glyphosphine
Glycine, N,N-bis(phosphonomethyl)-
Polaris
2-(bis(phosphonomethyl)amino)acetic acid
2-[bis(phosphonomethyl)amino]acetic acid
Glyphosine [ANSI]
Caswell No. 471A
CHEBI:63484
N,N-bis(phosphonomethyl)aminoacetic acid
Glyphosine [ANSI:ISO]
Glycine-N,N-bis(methylenephosphonic acid)
EINECS 219-468-4
EPA Pesticide Chemical Code 103602
UNII-2U96121SKR
BRN 1884944
2U96121SKR
GLYPHOSINE [MI]
GLYPHOSINE [ISO]
DTXSID2044557
OXHDYFKENBXUEM-UHFFFAOYSA-
MON-845
Glyphosine (ANSI)
GLYCINEDIMETHANEPHOSPHONIC ACID
NSC-18468
N,N-DI(PHOSPHONOMETHYL)GLYCINE
CP-41845
N,N-BIS(PHOSPHONOMETHYL)AMINOACETIC
Acetic acid, 2-bis(phosphonatomethyl)amino-
Glyphosine (ANSI:ISO)
NITRILOMONOMETHYLCARBONYLDIMETHYLPHOSPHONIC ACID
NITRILOMONOACETIC ACID DIMETHYLENEPHOSPHONIC ACID
DTXCID0024557
Glycine, N,N-bis(phosphonomethyl)-(7CI)(8CI)
Glycine, N,N-bis(phosphonomethyl)-(7CI)(8CI)(9CI)
219-468-4
inchi=1/c4h11no8p2/c6-4(7)1-5(2-14(8,9)10)3-15(11,12)13/h1-3h2,(h,6,7)(h2,8,9,10)(h2,11,12,13)
oxhdyfkenbxuem-uhfffaoysa-n
N,N-Bis(phosphonomethyl)glycine
CP 41845
Glycinedimethanephosphonic acid;C 9552; CP 41845; GDMP;Polaris
N-(Carboxymethyl)iminodi(methylphosphinic acid)
MFCD00056670
GDMP
Epitope ID:167841
SCHEMBL67368
CHEMBL265954
AKOS003600176
[Bis(phosphonomethyl)amino]acetic acid #
NCGC00160488-01
AC-12519
AS-15131
acetic acid, N,N-bis(phosphonomethyl)amino-
G0229
NS00082777
C19132
D90732
N,N-Bis(phosphonomethyl)glycine, >=98.0% (T)
Q27132652
[carboxymethyl(phosphonomethyl)azaniumyl]methyl-hydroxyphosphinate