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2-Bromo-1-methyl-4-nitroimidazole

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Identification
Molecular formula
C4H4BrN3O2
CAS number
75953-12-9
IUPAC name
2-bromo-1-methyl-4-nitro-imidazole
State
State

At room temperature, 2-Bromo-1-methyl-4-nitroimidazole is typically found in a solid state.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
307.00
Boiling point (Kelvin)
580.15
General information
Molecular weight
209.00g/mol
Molar mass
208.9950g/mol
Density
2.0060g/cm3
Appearence

2-Bromo-1-methyl-4-nitroimidazole typically appears as a pale yellow solid, though its exact hue can vary depending on the degree of purity and the presence of any impurities.

Comment on solubility

Solubility of 2-Bromo-1-Methyl-4-Nitro-Imidazole

2-Bromo-1-methyl-4-nitro-imidazole presents interesting characteristics regarding its solubility. Generally, the solubility of a compound is influenced by its molecular structure as well as the functional groups present. For this particular compound, the following points can be noted:

  • Polarity: The presence of the nitro group (-NO2) contributes to polar characteristics, potentially enhancing solubility in polar solvents like water.
  • Hydrophobicity: Conversely, the bromine substituent and the imidazole ring introduce hydrophobic features, which may hinder solubility in water.
  • Solvent Compatibility: This compound is likely to be more soluble in organic solvents such as ethanol and acetonitrile, where the balance of polar and nonpolar properties is more favorable.
  • Temperature Dependence: Solubility may improve with increasing temperature, as many compounds exhibit this behavior due to enhanced molecular movement.

In summary, while 2-bromo-1-methyl-4-nitro-imidazole may demonstrate moderate solubility in certain solvents, the degree will ultimately depend on the specific solvent environment and conditions applied. Understanding these nuances is crucial for applications in laboratories or the pharmaceutical industry.

Interesting facts

Interesting Facts about 2-Bromo-1-methyl-4-nitro-imidazole

2-bromo-1-methyl-4-nitro-imidazole is a fascinating compound that belongs to a class of organic chemicals known as imidazoles. This compound exhibits various properties and potential applications that make it a subject of interest for scientists and researchers alike.

Key Attributes:

  • Pharmacological Potential: Imidazole derivatives are known for their diverse biological activities. Compounds like 2-bromo-1-methyl-4-nitro-imidazole can serve as potential leads for developing new pharmaceuticals, particularly in the field of antimicrobial and antifungal agents.
  • Synthetic Applications: The presence of the nitro group (–NO2) and the bromo group (–Br) in this compound enhances its electrophilic character, making it a valuable intermediate in organic synthesis, including the production of more complex chemical structures.
  • Research Significance: Due to its unique structural characteristics, this compound has garnered attention in various studies focusing on reaction mechanisms and chemical reactivity, particularly in understanding the behavior of halogenated compounds in organic chemistry.

Unique Characteristics:

What makes 2-bromo-1-methyl-4-nitro-imidazole particularly intriguing is its dual functionality, where the imidazole ring system allows for various substitution reactions. Imidazole itself is often found in biological molecules, including histidine, a key amino acid in protein structures. The discovery and development of imidazole derivatives may lead to breakthroughs in medicinal chemistry.

As one researcher noted, "The exploration of imidazole derivatives, including bromo and nitro substitutions, opens up new horizons in both synthetic and medicinal chemistry."

The further investigation of this compound could contribute substantially to the development of new therapeutic agents, as well as improve our understanding of imidazole-related chemical behavior in various contexts.

Synonyms
16681-63-3
2-BROMO-1-METHYL-4-NITRO-1H-IMIDAZOLE
DTXSID20168191
NSC 347484
DTXCID9090682
2-bromo-1-methyl-4-nitroimidazole
NSC347484
2-bromo-N-methylnitroimidazole
SCHEMBL3282371
NSC-347484
imidazole, 2-bromo-1-methyl-4-nitro-
DB-409226