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2-Bromo-3-chlorobenzoic acid

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Identification
Molecular formula
C7H4BrClO2
CAS number
6280-07-1
IUPAC name
2-bromo-3-chloro-benzoic acid
State
State

At room temperature, 2-bromo-3-chlorobenzoic acid is in a solid state, typically as a crystalline powder.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
327.00
Boiling point (Kelvin)
600.15
General information
Molecular weight
237.45g/mol
Molar mass
237.4450g/mol
Density
1.8040g/cm3
Appearence

2-Bromo-3-chlorobenzoic acid appears as a white to off-white crystalline solid. It is generally obtained as a powder and may have a faint characteristic odor typical of halogen-substituted benzoic acids.

Comment on solubility

Solubility of 2-bromo-3-chloro-benzoic acid

2-bromo-3-chloro-benzoic acid, with the chemical formula C7H4BrClO2, demonstrates unique solubility characteristics that are influenced by its functional groups and overall structure.

In general, this compound is considered to be:

  • Moderately soluble in polar solvents such as water, owing to the presence of the carboxylic acid group which can form hydrogen bonds.
  • More soluble in organic solvents like ethanol and acetone due to its nonpolar hydrocarbon region.

Factors affecting solubility include:

  • **Polarity:** The balance between hydrophilic (water-attracting) and hydrophobic (water-repelling) regions dictates its overall solubility.
  • **Temperature:** Increased temperature often enhances solubility for many compounds.
  • **pH of the solvent:** The acid functionality may ionize at higher pH levels, affecting solubility.

In summary, while 2-bromo-3-chloro-benzoic acid may show limited solubility in water, its behavior in organic solvents, particularly at varying temperatures and pH levels, can significantly alter its solubility profile.

Interesting facts

Interesting Facts about 2-bromo-3-chloro-benzoic acid

2-bromo-3-chloro-benzoic acid is a fascinating compound that exemplifies the diversity of halogenated aromatic carboxylic acids. Here are some intriguing aspects:

  • Halogenation Characteristics: The presence of both bromine and chlorine in its structure makes this compound a notable example of halogenated compounds, which often exhibit unique reactivity and properties that differ significantly from their non-halogenated counterparts.
  • Applications in Synthesis: This compound serves as an important intermediate in the synthesis of pharmaceuticals and agrochemicals. Its halogen substituents can be modified to create a variety of functional groups through electrophilic substitution reactions, making it a versatile building block in organic synthesis.
  • Biological Activity: Emerging research suggests that derivatives of 2-bromo-3-chloro-benzoic acid may exhibit significant biological activity. Some studies have proposed potential antimicrobial and antifungal properties, highlighting an area of interest for medicinal chemists.
  • Environmental Impact: Like many halogenated compounds, the environmental implications of 2-bromo-3-chloro-benzoic acid should not be overlooked. Studies are ongoing to evaluate its persistence and potential ecological effects, emphasizing the importance of responsible usage and disposal.

In summary, the study of 2-bromo-3-chloro-benzoic acid illustrates the intricate interplay between molecular structure and reactivity. As scientists continue to explore halogenated compounds, they uncover new possibilities for their application in various fields ranging from agriculture to pharmaceuticals.

“The unique characteristics of aromatic compounds, especially with halogen substitutions, open up an intriguing world of chemical possibilities.”

Synonyms
2-bromo-3-chlorobenzoic acid
56961-26-3
DTXSID20275016
RefChem:257041
DTXCID00226465
806-645-1
2-Bromo-3-chlorobenzoicacid
25638-14-6
MFCD00672931
2-bromo-3-chloro-benzoic Acid
Benzoic acid, 2-bromo-3-chloro-
Benzoicacid,2-bromo-3-chloro-
SCHEMBL2303377
SITHNMNGOHVILG-UHFFFAOYSA-N
BCP28601
CL8022
SBB098461
AKOS015834878
CS-W005157
DS-12728
SY024816
DB-364730
EN300-105772
F038275
Buttpark 22\01-98;2-Bromo-3-chlorobenzoic acid;