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2-Bromo-4-chlorobenzoic acid

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Identification
Molecular formula
C7H4BrClO2
CAS number
613-55-6
IUPAC name
2-bromo-4-chloro-benzoic acid
State
State

In its pure form, 2-Bromo-4-chlorobenzoic acid is typically found as a crystalline solid at room temperature.

Melting point (Celsius)
209.00
Melting point (Kelvin)
482.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
249.45g/mol
Molar mass
249.4510g/mol
Density
1.8130g/cm3
Appearence

2-Bromo-4-chlorobenzoic acid is a white to off-white crystalline powder. It is typically odorless and can be found in solid crystalline form.

Comment on solubility

Solubility of 2-bromo-4-chloro-benzoic acid

2-bromo-4-chloro-benzoic acid is an interesting compound when it comes to its solubility characteristics. Generally speaking, the solubility of this compound can be influenced by various factors due to the presence of halogen substituents and the carboxylic acid functional group.

  • Polar Nature: The carboxylic acid group (-COOH) contributes to the polar nature of the compound, increasing its ability to dissolve in polar solvents like water.
  • Effect of Halogens: The bromine and chlorine substituents can also affect the overall solubility. While halogens generally increase hydrophobic character, their positions on the aromatic ring modify the electronic distribution, influencing solubility behavior.
  • Solvent Interaction: 2-bromo-4-chloro-benzoic acid is expected to dissolve effectively in solvents such as ethanol and acetone due to favorable interactions between the polar groups in the compound and the solvent molecules.

In summary, while 2-bromo-4-chloro-benzoic acid shows moderate solubility in polar solvents, its solubility can also be limited in non-polar environments. Thus, it is crucial to consider both molecular structure and solvent characteristics when evaluating solubility.

Interesting facts

Interesting Facts about 2-Bromo-4-chloro-benzoic Acid

2-Bromo-4-chloro-benzoic acid is an intriguing compound with a variety of applications in scientific research and industry. This compound is part of the benzoic acid family, serving as a precursor for the synthesis of numerous other chemical products. Here are some key insights into this fascinating compound:

  • Versatile Intermediate: It is widely used in the pharmaceutical industry to synthesize bioactive compounds, including anti-inflammatory agents and antimicrobial substances.
  • Regulatory Role: The presence of bromine and chlorine atoms in its structure contributes to the compound's unique properties, influencing the reactivity and stability of benzoic acid derivatives.
  • Environmental Chemistry: Research has indicated that halogenated benzoic acids may be involved in environmental processes, including the degradation of certain pollutants, highlighting their importance in green chemistry.
  • Research Applications: As a reagent, it is extensively used in organic synthesis for various coupling reactions, as well as in studies focusing on structure-activity relationships in drug design.

Furthermore, the study of 2-bromo-4-chloro-benzoic acid not only enhances our understanding of organic chemistry but also opens avenues for innovative applications that can contribute to the development of sustainable practices in chemistry. Its unique halogenated structure serves as an ideal model for both academic investigation and practical application in diverse fields.

As we continue to explore its properties and potential uses, the importance of compounds like 2-bromo-4-chloro-benzoic acid in modern chemistry remains undisputed. The ability to synthesize and manipulate such compounds is key to advancing both scientific knowledge and technological progress.

Synonyms
2-Bromo-4-chlorobenzoic acid
936-08-3
DTXSID00275019
RefChem:466499
DTXCID20226467
627-328-2
2-bromo-4-chloro-benzoic Acid
MFCD00672930
2-Bromo-4-chlorobenzoicacid
Benzoic acid, 2-bromo-4-chloro-
4-bromo-2-chlorobenzoic acid/2-bromo-4-chlorobenzoic acid
4-chloro-2-bromobenzoic acid
p-chloro(bromo)benzoic acid
2-Bromo-4chlorobenzoic acid
2-Bromo-4-chloro-benzoicacid
SCHEMBL395189
SCHEMBL11810626
BCP15958
BBL101359
SBB063375
STL555155
2-Bromo-4-chlorobenzoic acid, 97%
AKOS005215803
AC-3903
CS-W002662
FB38481
PB48319
PS-7660
BP-20255
SY016936
DB-024287
A4668
B4592
EN300-98064
936B083
F018254
Z1269165449
2-bromo-4-chlorobenzoic acid/4-bromo-2-chlorobenzoic acid
4-bromo-2-chlobenzoic acid/ 2-bromo-4-chlorobenzoic acid